• 1159 Citations
  • 20 h-Index
19982019
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Research Output 1998 2019

  • 1159 Citations
  • 20 h-Index
  • 58 Article
  • 6 Letter
  • 6 Review article
  • 1 Comment/debate
2019

A unique system that can sensitively assess the risk of chemical leukoderma by using murine tail skin

Iida, M., Tazaki, A., Deng, Y., Chen, W., Yajima, I., Kondo-Ida, L., Hashimoto, K., Ohgami, N. & Kato, M., 2019 Nov 1, In : Chemosphere. 235, p. 713-718 6 p.

Research output: Contribution to journalArticle

skin
Skin
ketone
Ketones
Melanin
1 Citation (Scopus)

Chromium-mediated hyperpigmentation of skin in male tannery workers in Bangladesh

Al Hossain, M. M. A., Yajima, I., Tazaki, A., Xu, H., Saheduzzaman, M., Ohgami, N., Ahsan, N., Akhand, A. A. & Kato, M., 2019 Aug 1, In : Chemosphere. 229, p. 611-617 7 p.

Research output: Contribution to journalArticle

Chromium
chromium
skin
Skin
hair

Hearing loss in humans drinking tube well water with high levels of iron in arsenic–polluted area

He, T., Ohgami, N., Li, X., Yajima, I., Negishi-Oshino, R., Kato, Y., Ohgami, K., Xu, H., Ahsan, N., Akhand, A. A. & Kato, M., 2019 Dec 1, In : Scientific Reports. 9, 1, 9028.

Research output: Contribution to journalArticle

Open Access

Inhibition of mast cell degranulation by melanin

Kawamoto, Y., Kondo, H., Hasegawa, M., Kurimoto, C., Ishii, Y., Kato, C., Botei, T., Shinya, M., Murate, T., Ueno, Y., Kawabe, M., Goto, Y., Yamamoto, R., Iida, M., Yajima, I., Ohgami, N., Kato, M. & Takeda, K., 2019 May 1, In : Biochemical Pharmacology. 163, p. 178-193 16 p.

Research output: Contribution to journalArticle

Melanins
Immunoglobulin E
Antigens
Nanoparticles
Recovery
2018
16 Citations (Scopus)

A comprehensive study including monitoring, assessment of health effects and development of a remediation method for chromium pollution

Yoshinaga, M., Ninomiya, H., Al Hossain, M. M. A., Sudo, M., Akhand, A. A., Ahsan, N., Alim, M. A., Khalequzzaman, M., Iida, M., Yajima, I., Ohgami, N. & Kato, M., 2018 Jun 1, In : Chemosphere. 201, p. 667-675 9 p.

Research output: Contribution to journalArticle

Chromium
Remediation
chromium
Pollution
remediation
1 Citation (Scopus)

A disadvantageous effect of adsorption of barium by melanin on transforming activity

Omata, Y., Yoshinaga, M., Yajima, I., Ohgami, N., Hashimoto, K., Higashimura, K., Tazaki, A. & Kato, M., 2018 Nov 1, In : Chemosphere. 210, p. 384-391 8 p.

Research output: Contribution to journalArticle

Melanin
melanin
Melanins
barium
Barium
5 Citations (Scopus)

Arsenic level in toenails is associated with hearing loss in humans

Li, X., Ohgami, N., Yajima, I., Xu, H., Iida, M., Oshino, R., Ninomiya, H., Shen, D., Ahsan, N., Akhand, A. A. & Kato, M., 2018 Jul 1, In : PLoS ONE. 13, 7, e0198743.

Research output: Contribution to journalArticle

Open Access
Audition
Arsenic
hearing
arsenic
Nails
6 Citations (Scopus)

Arsenic levels in cutaneous appendicular organs are correlated with digitally evaluated hyperpigmented skin of the forehead but not the sole in Bangladesh residents

Yajima, I., Ahsan, N., Akhand, A. A., Al Hossain, M. A., Yoshinaga, M., Ohgami, N., Iida, M., Oshino, R., Naito, M., Wakai, K. & Kato, M., 2018 Jan 1, In : Journal of Exposure Science and Environmental Epidemiology. 28, 1, p. 64-68 5 p.

Research output: Contribution to journalArticle

Arsenic
Skin
Water
Spectrophotometers
3 Citations (Scopus)

Increased expression level of Hsp70 in the inner ears of mice by exposure to low frequency noise

Ninomiya, H., Ohgami, N., Oshino, R., Kato, M., Ohgami, K., Li, X., Shen, D., Iida, M., Yajima, I., Angelidis, C. E., Adachi, H., Katsuno, M., Sobue, G. & Kato, M., 2018 Jun 1, In : Hearing Research. 363, p. 49-54 6 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Label-free imaging of melanoma with confocal photothermal microscopy: Differentiation between malignant and benign tissue

Kobayashi, T., Nakata, K., Yajima, I., Kato, M. & Tsurui, H., 2018 Sep 1, In : Bioengineering. 5, 3, 67.

Research output: Contribution to journalArticle

Open Access
Confocal microscopy
Labels
Pumps
Tissue
Imaging techniques
3 Citations (Scopus)

Manganese in toenails is associated with hearing loss at high frequencies in humans

Ohgami, N., Li, X., Yajima, I., Oshino, R., Ohgami, K., Kato, Y., Ahsan, N., Akhand, A. A. & Kato, M., 2018 Aug 18, In : Biomarkers. 23, 6, p. 533-539 7 p.

Research output: Contribution to journalArticle

Audition
Manganese
Biomarkers
Nails
Inductively coupled plasma
2017
6 Citations (Scopus)

Arsenic-mediated hyperpigmentation in skin via NF-kappa B/endothelin-1 signaling in an originally developed hairless mouse model

Yajima, I., Kumasaka, M. Y., Iida, M., Oshino, R., Tanihata, H., Al Hossain, A., Ohgami, N. & Kato, M., 2017 Nov 1, In : Archives of Toxicology. 91, 11, p. 3507-3516 10 p.

Research output: Contribution to journalArticle

NF-kappa B
Arsenic
Endothelin-1
Skin
Endothelin A Receptors
1 Citation (Scopus)

Manganese-Mediated Decrease in Levels of c-RET and Tyrosine Hydroxylase Expression In Vitro

Kumasaka, M. Y., Yajima, I., Ohgami, N., Ninomiya, H., Iida, M., Li, X., Oshino, R., Tanihata, H., Yoshinaga, M. & Kato, M., 2017 Nov 1, In : Neurotoxicity Research. 32, 4, p. 661-670 10 p.

Research output: Contribution to journalArticle

Tyrosine 3-Monooxygenase
Manganese
Proteins
Dopamine
Phosphotransferases
8 Citations (Scopus)

Oral exposure to arsenic causes hearing loss in young people aged 12-29 years and in young mice

Li, X., Ohgami, N., Omata, Y., Yajima, I., Iida, M., Oshino, R., Ohnuma, S., Ahsan, N., Akhand, A. A. & Kato, M., 2017 Dec 1, In : Scientific Reports. 7, 1, 6844.

Research output: Contribution to journalArticle

Open Access

Research on Hygiene Based on Fieldwork and Experimental Studies

Yajima, I., 2017 Jan 1, In : Nihon eiseigaku zasshi. Japanese journal of hygiene. 72, 1, p. 49-54 6 p.

Research output: Contribution to journalReview article

Open Access
4 Citations (Scopus)

Risk assessment of neonatal exposure to low frequency noise based on balance in mice

Ohgami, N., Oshino, R., Ninomiya, H., Li, X., Kato, M., Yajima, I. & Kato, M., 2017 Feb 22, In : Frontiers in Behavioral Neuroscience. 11, 30.

Research output: Contribution to journalArticle

Open Access
2016
16 Citations (Scopus)

Epidemiological analysis of the association between hearing and barium in humans

Ohgami, N., Mitsumatsu, Y., Ahsan, N., Akhand, A. A., Li, X., Iida, M., Yajima, I., Naito, M., Wakai, K., Ohnuma, S. & Kato, M., 2016 Sep 1, In : Journal of Exposure Science and Environmental Epidemiology. 26, 5, p. 488-493 6 p.

Research output: Contribution to journalArticle

Audition
Barium
Arsenic
Regression analysis
Logistics

Limited effectiveness of household sand filters for removal of arsenic from well water in North Vietnam

Ilmiawati, C., Thang, N. D., Iida, M., Maeda, M., Ohnuma, S., Yajima, I., Ohgami, N., Oshino, R., Al Hossain, M. M. A., Ninomiya, H. & Kato, M., 2016 Dec 1, In : Journal of Water and Health. 14, 6, p. 1032-1040 9 p.

Research output: Contribution to journalArticle

Open Access
well water
arsenic
filter
sand
barium
9 Citations (Scopus)

Manganese-mediated acceleration of age-related hearing loss in mice

Ohgami, N., Yajima, I., Iida, M., Li, X., Oshino, R., Kumasaka, M. Y. & Kato, M., 2016 Nov 8, In : Scientific Reports. 6, 36306.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

Modulated expression levels of tyrosine kinases in spontaneously developed melanoma by single irradiation of non-thermal atmospheric pressure plasmas

Omata, Y., Iida, M., Yajima, I., Ohgami, N., Maeda, M., Ninomiya, H., Oshino, R., Tsuzuki, T., Hori, M. & Kato, M., 2016 Jan 1, In : International Journal of Clinical and Experimental Pathology. 9, 2, p. 1061-1067 7 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)

Prevention of allergic rhinitis by ginger and the molecular basis of immunosuppression by 6-gingerol through T cell inactivation

Kawamoto, Y., Ueno, Y., Nakahashi, E., Obayashi, M., Sugihara, K., Qiao, S., Iida, M., Kumasaka, M. Y., Yajima, I., Goto, Y., Ohgami, N., Kato, M. & Takeda, K., 2016 Jan 1, In : Journal of Nutritional Biochemistry. 27, p. 112-122 11 p.

Research output: Contribution to journalArticle

T-cells
Ovalbumin
Allergies
Ionomycin
Cytokines
11 Citations (Scopus)

Transcription factor LSF (TFCP2) inhibits melanoma growth

Goto, Y., Yajima, I., Kumasaka, M., Ohgami, N., Tanaka, A., Tsuzuki, T., Inoue, Y., Fukushima, S., Ihn, H., Kyoya, M., Ohashi, H., Kawakami, T., Bennett, D. C. & Kato, M., 2016 Jan 1, In : Oncotarget. 7, 3, p. 2379-2390 12 p.

Research output: Contribution to journalArticle

Open Access
2015
1 Citation (Scopus)

Analysis of heavy-metal-mediated disease and development of a novel remediation system based on fieldwork and experimental research

Yajima, I., Zou, C., Li, X., Nakano, C., Omata, Y. & Kumasaka, M. Y., 2015 Jan 1, In : Nihon eiseigaku zasshi. Japanese journal of hygiene. 70, 2, p. 105-109 5 p.

Research output: Contribution to journalReview article

Open Access
12 Citations (Scopus)

Arsenite-Mediated Promotion of Anchorage-Independent Growth of HaCaT Cells through Placental Growth Factor

Yajima, I., Kumasaka, M. Y., Ohnuma, S., Ohgami, N., Naito, H., Shekhar, H. U., Omata, Y. & Kato, M., 2015 Apr 20, In : Journal of Investigative Dermatology. 135, 4, p. 1147-1156 10 p.

Research output: Contribution to journalArticle

Open Access
Intercellular Signaling Peptides and Proteins
Extracellular Signal-Regulated MAP Kinases
Cells
Arsenic
Vascular Endothelial Growth Factor A
20 Citations (Scopus)

Carcinogenic risk of chromium, copper and arsenic in CCA-treated wood

Ohgami, N., Yamanoshita, O., Thang, N. D., Yajima, I., Nakano, C., Wenting, W., Ohnuma, S. & Kato, M., 2015 Aug 14, In : Environmental Pollution. 206, p. 456-460 5 p.

Research output: Contribution to journalArticle

Arsenic
Chromium
Copper
Wood
Debris
6 Citations (Scopus)

Decreased expression levels of cell cycle regulators and matrix metalloproteinases in melanoma from RET-transgenic mice by single irradiation of non-equilibrium atmospheric pressure plasmas

Iida, M., Omata, Y., Nakano, C., Yajima, I., Tsuzuki, T., Ishikawa, K., Hori, M. & Kato, M., 2015 Jan 1, In : International Journal of Clinical and Experimental Pathology. 8, 8, p. 9326-9331 6 p.

Research output: Contribution to journalArticle

22 Citations (Scopus)

Deltex-3-like (DTX3L) stimulates metastasis of melanoma through FAK/PI3K/AKT but not MEK/ERK pathway

Thang, N. D., Yajima, I., Kumasaka, M. Y., Iida, M., Suzuki, T. & Kato, M., 2015 Jan 1, In : Oncotarget. 6, 16, p. 14290-14299 10 p.

Research output: Contribution to journalArticle

Development of Preventive Therapy by Clarification of Mechanisms of Environmental-Factor-Mediated Diseases

Kato, M., Omata, Y., Iida, M., Kumasaka, M. Y., Ohgami, N., Li, X., Zou, C., Nakano, C., Kato, Y., Ohgami, K., Ohnuma, S. & Yajima, I., 2015 Jan 1, In : Nihon eiseigaku zasshi. Japanese journal of hygiene. 70, 3, p. 176-180 5 p.

Research output: Contribution to journalReview article

Open Access
4 Citations (Scopus)

Enhanced constitutive invasion activity in human nontumorigenic keratinocytes exposed to a low level of barium for a long time

Thang, N. D., Yajima, I., Ohnuma, S., Ohgami, N., Kumasaka, M. Y., Ichihara, G. & Kato, M., 2015 Feb 1, In : Environmental Toxicology. 30, 2, p. 161-167 7 p.

Research output: Contribution to journalArticle

barium
Barium
Matrix Metalloproteinase 14
Focal Adhesion Protein-Tyrosine Kinases
adhesion
33 Citations (Scopus)

Plasma with high electron density and plasma-activated medium for cancer treatment

Tanaka, H., Mizuno, M., Ishikawa, K., Kondo, H., Takeda, K., Hashizume, H., Nakamura, K., Utsumi, F., Kajiyama, H., Kano, H., Okazaki, Y., Toyokuni, S., Akiyama, S., Maruyama, S., Yamada, S., Kodera, Y., Kaneko, H., Terasaki, H., Hara, H., Adachi, T. & 5 others, Iida, M., Yajima, I., Kato, M., Kikkawa, F. & Hori, M., 2015 Dec 1, In : Clinical Plasma Medicine. 3, 2, p. 72-76 5 p.

Research output: Contribution to journalArticle

electron plasma
cancer
therapy
tumors
medical science
8 Citations (Scopus)

Treatment of vemurafenib-resistant SKMEL-28 melanoma cells with paclitaxel

Thang, N. D., Nghia, P. T., Kumasaka, M. Y., Yajima, I. & Kato, M., 2015 Jan 1, In : Asian Pacific Journal of Cancer Prevention. 16, 2, p. 699-705 7 p.

Research output: Contribution to journalArticle

Open Access
2014
7 Citations (Scopus)

Actin-binding protein, espin: A novel metastatic regulator for melanoma

Yanagishita, T., Yajima, I., Kumasaka, M., Kawamoto, Y., Tsuzuki, T., Matsumoto, Y., Watanabe, D. & Kato, M., 2014 Jan 1, In : Molecular Cancer Research. 12, 3, p. 440-446 7 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

An actin-binding protein Espin is a growth regulator for melanoma

Yanagishita, T., Yajima, I., Kumasaka, M., Iida, M., Xiang, L., Tamada, Y., Matsumoto, Y., Watanabe, D. & Kato, M., 2014 Dec 13, In : Journal of Investigative Dermatology. 134, 12, p. 2996-2999 4 p.

Research output: Contribution to journalLetter

Open Access
7 Citations (Scopus)

Bidirectional functions of arsenic as a carcinogen and an anti-cancer agent in human squamous cell carcinoma

Thang, N. D., Yajima, I., Kumasaka, M. Y. & Kato, M., 2014 May 9, In : PLoS ONE. 9, 5, e96945.

Research output: Contribution to journalArticle

Open Access
antineoplastic agents
squamous cell carcinoma
Arsenic
carcinogens
arsenic
7 Citations (Scopus)

Commentary to Krishna et al. (2014): Brain deposition and neurotoxicity of manganese in adult mice exposed via the drinking water

Kumasaka, M. Y., Yajima, I., Ohgami, N., Naito, H., Omata, Y. & Kato, M., 2014 Jan 1, In : Archives of Toxicology. 88, 5, p. 1185-1186 2 p.

Research output: Contribution to journalLetter

Manganese
Drinking Water
Brain
Metabolites
Serotonin
25 Citations (Scopus)

Non-equilibrium atmospheric pressure plasmas modulate cell cycle-related gene expressions in melanocytic tumors of RET-transgenic mice

Yajima, I., Iida, M., Kumasaka, M. Y., Omata, Y., Ohgami, N., Chang, J., Ichihara, S., Hori, M. & Kato, M., 2014 Jan 1, In : Experimental Dermatology. 23, 6, p. 424-425 2 p.

Research output: Contribution to journalArticle

Open Access
Gene expression
Atmospheric pressure
Tumors
Cells
Plasmas
14 Citations (Scopus)

Non-thermal atmospheric pressure plasmas as a novel candidate for preventive therapy of melanoma

Omata, Y., Iida, M., Yajima, I., Takeda, K., Ohgami, N., Hori, M. & Kato, M., 2014 Sep 18, In : Environmental Health and Preventive Medicine. 19, 5, p. 367-369 3 p.

Research output: Contribution to journalArticle

Open Access
9 Citations (Scopus)

The effects of non-thermal atmospheric pressure plasma irradiation on expression levels of matrix metalloproteinases in benign melanocytic tumors in RET-transgenic mice

Iida, M., Yajima, I., Ohgami, N., Tamura, H., Takeda, K., Ichihara, S., Hori, M. & Kato, M., 2014 Jan 1, In : European Journal of Dermatology. 24, 3, p. 392-394 3 p.

Research output: Contribution to journalLetter

2013
9 Citations (Scopus)

A Subpopulation of Smooth Muscle Cells, Derived from Melanocyte-Competent Precursors, Prevents Patent Ductus Arteriosus

Yajima, I., Colombo, S., Puig, I., Champeval, D., Kumasaka, M., Belloir, E., Bonaventure, J., Mark, M., Yamamoto, H., Taketo, M. M., Choquet, P., Etchevers, H. C., Beermann, F., Delmas, V., Monassier, L. & Larue, L., 2013 Jan 31, In : PLoS ONE. 8, 1, e53183.

Research output: Contribution to journalArticle

Open Access
ductus arteriosus
patent ductus arteriosus
melanocytes
smooth muscle
myocytes
20 Citations (Scopus)

Comparison of Barium and Arsenic Concentrations in Well Drinking Water and in Human Body Samples and a Novel Remediation System for These Elements in Well Drinking Water

Kato, M., Kumasaka, M. Y., Ohnuma, S., Furuta, A., Kato, Y., Shekhar, H. U., Kojima, M., Koike, Y., Dinh Thang, N., Ohgami, N., Ly, T. B., Jia, X., Yetti, H., Naito, H., Ichihara, G. & Yajima, I., 2013 Jun 21, In : PLoS ONE. 8, 6, e66681.

Research output: Contribution to journalArticle

Open Access
barium
Arsenic
Barium
remediation
arsenic
20 Citations (Scopus)

Enhanced carcinogenicity by coexposure to arsenic and iron and a novel remediation system for the elements in well drinking water

Kumasaka, M. Y., Yamanoshita, O., Shimizu, S., Ohnuma, S., Furuta, A., Yajima, I., Nizam, S., Khalequzzaman, M., Shekhar, H. U., Nakajima, T. & Kato, M., 2013 Mar 1, In : Archives of Toxicology. 87, 3, p. 439-447 9 p.

Research output: Contribution to journalArticle

Arsenic
Remediation
Drinking Water
Iron
hydrotalcite
6 Citations (Scopus)

Hearing impairments caused by genetic and environmental factors

Ohgami, N., Iida, M., Yajima, I., Tamura, H., Ohgami, K. & Kato, M., 2013 Jan 1, In : Environmental Health and Preventive Medicine. 18, 1, p. 10-15 6 p.

Research output: Contribution to journalReview article

Open Access
2012
9 Citations (Scopus)

A novel hairless mouse model for malignant melanoma

Thang, N. D., Yajima, I., Nakagawa, K., Tsuzuki, T., Kumasaka, M. Y., Ohgami, N., Ly, T. B., Iwamoto, T., Watanabe, D. & Kato, M., 2012 Mar 1, In : Journal of Dermatological Science. 65, 3, p. 207-212 6 p.

Research output: Contribution to journalArticle

Tumors
Animals
Biomarkers
Binders
Skin
16 Citations (Scopus)

Barium inhibits arsenic-mediated apoptotic cell death in human squamous cell carcinoma cells

Yajima, I., Uemura, N., Nizam, S., Khalequzzaman, M., Thang, N. D., Kumasaka, M. Y., Akhand, A. A., Shekhar, H. U., Nakajima, T. & Kato, M., 2012 Jun 1, In : Archives of Toxicology. 86, 6, p. 961-973 13 p.

Research output: Contribution to journalArticle

Arsenic
Cell death
Barium
Cells
Apoptosis
24 Citations (Scopus)

Chronic exposure to low frequency noise at moderate levels causes impaired balance in mice

Tamura, H., Ohgami, N., Yajima, I., Iida, M., Ohgami, K., Fujii, N., Itabe, H., Kusudo, T., Yamashita, H. & Kato, M., 2012 Jun 29, In : PLoS ONE. 7, 6, e39807.

Research output: Contribution to journalArticle

Open Access
chronic exposure
Oxidative stress
Acoustic waves
mice
Cells
3 Citations (Scopus)

C-Ret-mediated hearing losses

Ohgami, N., Tamura, H., Ohgami, K., Iida, M., Yajima, I., Kumasaka, M. Y., Goto, Y., Sone, M., Nakashima, T. & Kato, M., 2012 Feb 13, In : International Journal of Clinical and Experimental Pathology. 5, 1, p. 23-28 6 p.

Research output: Contribution to journalReview article

7 Citations (Scopus)

Functional analysis of GNG2 in human malignant melanoma cells

Yajima, I., Kumasaka, M. Y., Tamura, H., Ohgami, N. & Kato, M., 2012 Dec 1, In : Journal of Dermatological Science. 68, 3, p. 172-178 7 p.

Research output: Contribution to journalArticle

Heterotrimeric GTP-Binding Proteins
Signal transduction
Functional analysis
GTP-Binding Proteins
Dimers
25 Citations (Scopus)

Otx2 Is Involved in the Regional Specification of the Developing Retinal Pigment Epithelium by Preventing the Expression of Sox2 and Fgf8, Factors That Induce Neural Retina Differentiation

Nishihara, D., Yajima, I., Tabata, H., Nakai, M., Tsukiji, N., Katahira, T., Takeda, K., Shibahara, S., Nakamura, H. & Yamamoto, H., 2012 Nov 8, In : PLoS ONE. 7, 11, e48879.

Research output: Contribution to journalArticle

Open Access
Retinal Pigments
retina
epithelium
pigments
Specifications
75 Citations (Scopus)

RAS/RAF/MEK/ERK and PI3K/PTEN/AKT signaling in malignant melanoma progression and therapy

Yajima, I., Kumasaka, M. Y., Thang, N. D., Goto, Y., Takeda, K., Yamanoshita, O., Iida, M., Ohgami, N., Tamura, H., Kawamoto, Y. & Kato, M., 2012 Dec 1, In : Dermatology Research and Practice. 2012, 354191.

Research output: Contribution to journalReview article

Open Access
2011
16 Citations (Scopus)

Barium promotes anchorage-independent growth and invasion of human HaCaT keratinocytes via activation of c-SRC kinase

Thang, N. D., Yajima, I., Kumasaka, M. Y., Ohnuma, S., Yanagishita, T., Hayashi, R., Shekhar, H. U., Watanabe, D. & Kato, M., 2011 Oct 12, In : PLoS ONE. 6, 10, e25636.

Research output: Contribution to journalArticle

Open Access
barium
keratinocytes
Barium
phosphotransferases (kinases)
Phosphotransferases