• 6824 Citations
  • 49 h-Index
19982019

Research output per year

If you made any changes in Pure these will be visible here soon.

Research Output

  • 6824 Citations
  • 49 h-Index
  • 130 Article
  • 1 Chapter
Filter
Article
2004

Anti-inflammatory and anti-allergic effect of rosmarinic acid (RA); Inhibition of seasonal allergic rhinoconjunctivitis (SAR) and its mechanism

Osakabe, N., Takano, H., Sanbongi, C., Yasuda, A., Yanagisawa, R., Inoue, K. I. & Yoshikawa, T., 2004, In : BioFactors. 21, 1-4, p. 127-131 5 p.

Research output: Contribution to journalArticle

93 Citations (Scopus)

Anti-inflammatory and anti-allergic effect of rosmarinic acid (RA); inhibition of seasonal allergic rhinoconjunctivitis (SAR) and its mechanism.

N, O., H., O. NT., C., S., A., Y., R., Y., K., I., T., Y. & Osakabe, N., 2004 Sep 1, In : Biofactors.. 21, p. 127-131

Research output: Contribution to journalArticle

93 Citations (Scopus)

Dose-response study of daily cocoa intake on the oxidative susceptibility of low-density lipoprotein in healthy human volunteers

Osakabe, N., Baba, S., Yasuda, A., Iwamoto, T., Kamiyama, M., Tokunaga, T. & Kondo, K., 2004 Dec, In : Journal of Health Science. 50, 6, p. 679-684 6 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

Dose-Response Study of Daily Cocoa Intake on the Oxidative Susceptibility of Low-Density Lipoprotein in Healthy Human Volunteers.

N, O., S., B., T., I., A., Y., M., K., K., K. & Osakabe, N., 2004 Sep 1, In : J. Health Sci.. 50, p. 679-684

Research output: Contribution to journalArticle

17 Citations (Scopus)

Extract of Perilla frutescens Enriched for Rosmarinic Acid, a Polyphenolic Phytochemical, Inhibits Seasonal Allergic Rhinoconjunctivitis in Humans

Takano, H., Osakabe, N., Sanbongi, C., Yanagisawa, R., Inoue, K. I., Yasuda, A., Natsume, M., Baba, S., Ichiishi, E. I. & Yoshikawa, T., 2004 Mar, In : Experimental Biology and Medicine. 229, 3, p. 247-254 8 p.

Research output: Contribution to journalArticle

102 Citations (Scopus)

Extract of Perilla frutescens enriched for rosmarinic acid, a polyphenolic phytochemical, inhibits seasonal allergic rhinoconjunctivitis in humans.

H., T., N, O., C., S., A., Y., R., Y., K., I., M., N., E., I., T., Y. & Osakabe, N., 2004 Mar 1, In : Exp. Biol. Med.. 229, p. 247-254

Research output: Contribution to journalArticle

102 Citations (Scopus)

Ingestion of Proanthocyanidins Derived from Cacao Inhibits Diabetes-Induced Cataract Formation in Rats

Osakabe, N., Yamagishi, M., Natsume, M., Yasuda, A. & Osawa, T., 2004 Jan, In : Experimental Biology and Medicine. 229, 1, p. 33-39 7 p.

Research output: Contribution to journalArticle

46 Citations (Scopus)

Ingestion of proanthocyanidins derived from cacao inhibits diabetes-induced cataract formation in rats.

N, O., M., Y., M, N., A, Y., T., O. & Osakabe, N., 2004 Jan 1, In : Exp. Biol. Med.. 229, p. 33-39

Research output: Contribution to journalArticle

46 Citations (Scopus)

In vitro antioxidative activity of ( - )-epicatechin glucuronide metabolites present in human and rat plasma

Natsume, M., Osakabe, N., Yasuda, A., Baba, S., Tokunaga, T., Kondo, K., Osawa, T. & Terao, J., 2004 Dec, In : Free Radical Research. 38, 12, p. 1341-1348 8 p.

Research output: Contribution to journalArticle

51 Citations (Scopus)

In vitro antioxidative activity of (-)-epicatechin glucuronide metabolites present in human and rat plasma.

M., N., N, O., A., Y., S., B., T., T., K., K., T., O., J., T. & Osakabe, N., 2004 Dec 1, In : Free Radic. Res.. 38, p. 1341-1348

Research output: Contribution to journalArticle

51 Citations (Scopus)
92 Citations (Scopus)

Rosmarinic acid inhibits epidermal inflammatory responses: Anticarcinogenic effect of Perilla frutescens extract in the murine two-stage skin model

Osakabe, N., Yasuda, A., Natsume, M. & Yoshikawa, T., 2004 Apr, In : Carcinogenesis. 25, 4, p. 549-557 9 p.

Research output: Contribution to journalArticle

165 Citations (Scopus)

Rosmarinic acid inhibits epidermal inflammatory responses: anticarcinogenic effect of Perilla frutescens extract in the murine two-stage skin model.

N, O., A., Y., M., N., T., Y. & Osakabe, N., 2004 Apr 1, In : Carcinogenesis. 25, p. 549-557

Research output: Contribution to journalArticle

165 Citations (Scopus)

Rosmarinic acid in perilla extract inhibits allergic inflammation induced by mite allergen, in a mouse model

Sanbongi, C., Takano, H., Osakabe, N., Sasa, N., Natsume, M., Yanagisawa, R., Inoue, K. I., Sadakane, K., Ichinose, T. & Yoshikawa, T., 2004, In : Clinical and Experimental Allergy. 34, 6, p. 971-977 7 p.

Research output: Contribution to journalArticle

100 Citations (Scopus)

Rosmarinic acid in perilla extract inhibits allergic inflammation induced by mite allergen, in a mouse model.

C., S., H., T., N, O., N., S., M., N., R., Y., K., I., K., S., T., I., T., Y. & Osakabe, N., 2004 Jun 1, In : Clin. Exp. Allergy. 34, p. 971-977

Research output: Contribution to journalArticle

100 Citations (Scopus)
2005

Absorption, metabolism, degradation and urinary excretion of rosmarinic acid after intake of Perilla frutescens extract in humans

Baba, S., Osakabe, N., Natsume, M., Yasuda, A., Muto, Y., Hiyoshi, K., Takano, H., Yoshikawa, T. & Terao, J., 2005 Jan, In : European Journal of Nutrition. 44, 1, p. 1-9 9 p.

Research output: Contribution to journalArticle

80 Citations (Scopus)

Absorption, metabolism, degradation and urinary excretion of rosmarinic acid after intake of Perilla frutescens extract in humans.

S., B., N, O., M., N., A., Y., Y., M., K., H., H., T., T., Y., J., T. & Osakabe, N., 2005 Feb 1, In : Europian Jounal of Nutrition. 44, p. 1-9

Research output: Contribution to journalArticle

Cacao polyphenols and atherosclerosis

Osakabe, N., 2005, In : Journal of Clinical Biochemistry and Nutrition. 37, 3, p. 67-72 6 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Physiological activity of cacao polyphenols

N, O., N., O., S., B., M., Y., T., T., T., T. J. O. & Osakabe, N., 2005 Dec 15, In : Default journal.

Research output: Contribution to journalArticle

Suppressive effect of cocoa powder on atherosclerosis in Kurosawa and Kusanagi-hypercholesterolemic rabbits.

Kurosawa, T., Itoh, F., Nozaki, A., Nakano, Y., Katsuda, S. I., Osakabe, N., Tsubone, H., Kondo, K. & Itakura, H., 2005, In : Journal of Atherosclerosis and Thrombosis. 12, 1, p. 20-28 9 p.

Research output: Contribution to journalArticle

47 Citations (Scopus)

Suppressive effects of cacao liquor polyphenols (CLP) on LDL oxidation and the development of atherosclerosis in Kurosawa and Kusanagi-hypercholesterolemic rabbits

Kurosawa, T., Itoh, F., Nozaki, A., Nakano, Y., Katsuda, S. I., Osakabe, N., Tsubone, H., Kondo, K. & Itakura, H., 2005 Apr, In : Atherosclerosis. 179, 2, p. 237-246 10 p.

Research output: Contribution to journalArticle

68 Citations (Scopus)

Suppressive effects of cacao liquor polyphenols (CLP) on LDL oxidation and the development of atherosclerosis in Kurosawa and Kusanagi-hypercholesterolemic rabbits.

Kurosawa, K., T., T., N, O., F., I., A., N., Y., N., S, K., H., T., K., K., H., I. & Osakabe, N., 2005 Apr 1, In : Atherosclerosis. 179, p. 237-246

Research output: Contribution to journalArticle

68 Citations (Scopus)
2006

A Cacao polyphenols on cardiovascular disease prevention

Osakabe, N., 2006 Nov 12, In : Kadota Fund International Forum 2006.

Research output: Contribution to journalArticle

Determination of rosmarinic acid and luteolin in Perilla frutescens Britton (Labiatae)

Natsume, M., Muto, Y., Fukuda, K., Tokunaga, T. & Osakabe, N., 2006 Apr 30, In : Journal of the Science of Food and Agriculture. 86, 6, p. 897-901 5 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)
2007

Continuous intake of polyphenolic compounds containing cocoa powder reduces LDL oxidative susceptibility and has beneficial effects on plasma HDL-cholesterol concentrations in humans

Baba, S., Osakabe, N., Kato, Y., Natsume, M., Yasuda, A., Kido, T., Fukuda, K., Muto, Y. & Kondo, K., 2007 Mar 1, In : American Journal of Clinical Nutrition. 85, 3, p. 709-717 9 p.

Research output: Contribution to journalArticle

193 Citations (Scopus)
193 Citations (Scopus)

Dietary supplementation with cacao liquor proanthocyanidins prevents elevation of blood glucose levels in diabetic obese mice

Tomaru, M., Takano, H., Osakabe, N., Yasuda, A., Inoue, K. I., Yanagisawa, R., Ohwatari, T. & Uematsu, H., 2007 Apr, In : Nutrition. 23, 4, p. 351-355 5 p.

Research output: Contribution to journalArticle

83 Citations (Scopus)

Plasma LDL and HDL cholesterol and oxidized LDL concentrations are altered in normo- and hypercholesterolemic humans after intake of different levels of cocoa powder

Baba, S., Natsume, M., Yasuda, A., Nakamura, Y., Tamura, T., Osakabe, N., Kanegae, M. & Kondo, K., 2007 Jun, In : Journal of Nutrition. 137, 6, p. 1436-1441 6 p.

Research output: Contribution to journalArticle

146 Citations (Scopus)

Plasma LDL and HDL cholesterol and oxidized LDL concentrations are altered in normo- and hypercholesterolemic humans after intake of different levels of cocoa powder.

S., B., M., N., A., Y., Y., N., T., T., M., K., K., K., N., O. & Osakabe, N., 2007 Jan 1, In : J. Nutr.. 137, p. 1436-1441

Research output: Contribution to journalArticle

146 Citations (Scopus)

Pulmonary exposure to diesel exhaust particles enhances fatty change of the liver in obese diabetic mice

Tomaru, M., Takano, H., Inoue, K. I., Yanagisawa, R., Osakabe, N., Yasuda, A., Shimada, A., Kato, Y. & Uematsu, H., 2007 Jan, In : International Journal of Molecular Medicine. 19, 1, p. 17-22 6 p.

Research output: Contribution to journalArticle

30 Citations (Scopus)

Recent Topics of Cacao Polyphenols on Metabolic Syndrome

Osakabe, N., 2007 Sep 14, In : Bio Korea 2007.

Research output: Contribution to journalArticle

Short-term supplementation with plant extracts rich in flavonoids protect nigrostriatal dopaminergic neurons in a rat model of Parkinson's disease

Datla, K. P., Zbarsky, V., Rai, D., Parkar, S., Osakabe, N., Aruoma, O. I. & Dexter, D. T., 2007 Aug, In : Journal of the American College of Nutrition. 26, 4, p. 341-349 9 p.

Research output: Contribution to journalArticle

61 Citations (Scopus)
2008

Cacao liquor proanthocyanidins inhibit lung injury induced by diesel exhaust particles

Yasuda, A., Takano, H., Osakabe, N., Sanbongi, C., Fukuda, K., Natsume, M., Yanagisawa, R., Inoue, K., Kato, Y., Osawa, T. & Yoshikawa, T., 2008 Apr, In : International Journal of Immunopathology and Pharmacology. 21, 2, p. 279-288 10 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Cacao liquor proanthocyanidins inhibit lung injury induced by diesel exhaust particles.

Yasuda, A., Yoshikawa, A. Y. H. N. C. & Osakabe, N., 2008 Jul 1, In : International Jounal of Immunopathological Pharmacolgy. 21, p. 279-288

Research output: Contribution to journalArticle

7 Citations (Scopus)

Cacao polyphenol extract suppresses transformation of an aryl hydrocarbon receptor in C57BL/6 mice

Mukai, R., Fukuda, I., Nishiumi, S., Natsume, M., Osakabe, N., Yoshida, K. I. & Ashida, H., 2008 Nov 12, In : Journal of Agricultural and Food Chemistry. 56, 21, p. 10399-10405 7 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Cacao polyphenol extract suppresses transformation of an aryl hydrocarbon receptor in C57BL/6 mice.

Mukai, R., Ashida, R. M. I. S. M. N. & Osakabe, N., 2008 Nov 1, In : Jounal of Agricalural Food Chemistry. 56, p. 10399-10405

Research output: Contribution to journalArticle

12 Citations (Scopus)

Effects of cacao liquor polyphenols on cardiovascular and autonomic nervous functions in hypercholesterolaemic rabbits

Akita, M., Kuwahara, M., Itoh, F., Nakano, Y., Osakabe, N., Kurosawa, T. & Tsubone, H., 2008 Dec, In : Basic and Clinical Pharmacology and Toxicology. 103, 6, p. 581-587 7 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Effects of cacao liquor polyphenols on cardiovascular and autonomic nervous functions in hypercholesterolaemic rabbits.

Akita, M., Tsubone, M. AM. F. Y. N. & Osakabe, N., 2008 Dec 1, In : Basic Clinical Pharmacology and Toxicology.. 103, p. 581-587

Research output: Contribution to journalArticle

11 Citations (Scopus)

Inhibitory effects of conjugated epicatechin metabolites on peroxynitrite-mediated nitrotyrosine formation

Natsume, M., Osakabe, N., Yasuda, A., Osawa, T. & Terao, J., 2008 Jan, In : Journal of Clinical Biochemistry and Nutrition. 42, 1, p. 50-53 4 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Inhibitory Effects of Conjugated Epicatechin Metabolites on Peroxynitrite-mediated Nitrotyrosine Formation.

Natsume, M., Terao, M. N. N. A. T. J. & Osakabe, N., 2008 Jan 1, In : Jounal of Clinical Biochemistry and Nutririon.. 42, p. 50-53

Research output: Contribution to journalArticle

10 Citations (Scopus)

Procyanidins in Theobroma cacao reduce plasma cholesterol levels in high cholesterol-fed rats

Osakabe, N. & Yamagishi, M., 2009 Sep, In : Journal of Clinical Biochemistry and Nutrition. 45, 2, p. 131-136 6 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Procyanidins in Theobroma cacao Reduce Plasma Cholesterol Levels in High Cholesterol-Fed Rats.

Osakabe, N. & Yamagishi, M., 2009 Aug 28, In : Jounal of Clinical Biochemstry and Nutrition.. 45, p. 131-136

Research output: Contribution to journalArticle

15 Citations (Scopus)
2010

Cacao polyphenols influence the regulation of apolipoprotein in hepg2 and caco2 cells

Yasuda, A., Natsume, M., Osakabe, N., Kawahata, K. & Koga, J., 2011 Feb 23, In : Journal of Agricultural and Food Chemistry. 59, 4, p. 1470-1476 7 p.

Research output: Contribution to journalArticle

32 Citations (Scopus)