• 4479 Citations
  • 42 h-Index
1985 …2019

Research output per year

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Research Output

  • 4479 Citations
  • 42 h-Index
  • 160 Article
  • 3 Review article
  • 2 Comment/debate
2019

Catalytic Enantioselective Synthesis of N-C Axially Chiral Sulfonamides through Chiral Palladium-Catalyzed N-Allylation

Kikuchi, Y., Nakamura, C., Matsuoka, M., Asami, R. & Kitagawa, O., 2019 Jun 21, In : Journal of Organic Chemistry. 84, 12, p. 8112-8120 9 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Chirality-dependent halogen bonds in axially chiral quinazolin-4-one derivatives bearing: Ortho -halophenyl groups

Imai, T., Niijima, E., Terada, S., Wzorek, A., Soloshonok, V. A., Hori, A. & Kitagawa, O., 2019 Jan 1, In : CrystEngComm. 21, 22, p. 3385-3389 5 p.

Research output: Contribution to journalArticle

N-C Axially Chiral Compounds with an ortho-Fluoro Substituent and Steric Discrimination between Hydrogen and Fluorine Atoms Based on a Diastereoselective Model Reaction

Iida, A., Matsuoka, M., Hasegawa, H., Vanthuyne, N., Farran, D., Roussel, C. & Kitagawa, O., 2019 Mar 15, In : Journal of Organic Chemistry. 84, 6, p. 3169-3175 7 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

The self-disproportionation of enantiomers (SDE) of α-amino acid derivatives: facets of steric and electronic properties

Hosaka, T., Imai, T., Wzorek, A., Marcinkowska, M., Kolbus, A., Kitagawa, O., Soloshonok, V. A. & Klika, K. D., 2019 Feb 7, In : Amino Acids. 51, 2, p. 283-294 12 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)
2018

Chemistry of 2,4,6-tri-tert-butylanilides possessing isolable rotational isomer

Ototake, N. & Kitagawa, O., 2018 Jan 1, In : Yuki Gosei Kagaku Kyokaishi/Journal of Synthetic Organic Chemistry. 76, 6, p. 575-583 9 p.

Research output: Contribution to journalReview article

N−C Axially Chiral Anilines: Electronic Effect on Barrier to Rotation and A Remote Proton Brake

Iwasaki, Y., Morisawa, R., Yokojima, S., Hasegawa, H., Roussel, C., Vanthuyne, N., Caytan, E. & Kitagawa, O., 2018 Mar 20, In : Chemistry - A European Journal. 24, 17, p. 4453-4458 6 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

The self-disproportionation of enantiomers (SDE): A menace or an opportunity?

Han, J., Kitagawa, O., Wzorek, A., Klika, K. D. & Soloshonok, V. A., 2018 Feb 21, In : Chemical Science. 9, 7, p. 1718-1739 22 p.

Research output: Contribution to journalReview article

33 Citations (Scopus)
2 Citations (Scopus)
2017

Diastereoselective α-Alkylation of Metallo Enamines Generated from N-C Axially Chiral Mebroqualone Derivatives

Matsuoka, M., Goto, M., Wzorek, A., Soloshonok, V. A. & Kitagawa, O., 2017 May 19, In : Organic Letters. 19, 10, p. 2650-2653 4 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Possible Case of Halogen Bond-Driven Self-Disproportionation of Enantiomers (SDE) via Achiral Chromatography

Terada, S., Hirai, M., Honzawa, A., Kitagawa, O., Kamizela, A., Wzorek, A. & Soloshonok, V. A., 2017 Oct 17, In : Chemistry - A European Journal. 23, 58, p. 14631-14638 8 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Specific reactivity of 2,4,6-tri-tert-butylanilide anions and its application to benzylation reagent

Yamada, T., Tsukagoshi, S. & Kitagawa, O., 2017 Jan 25, In : Tetrahedron Letters. 58, 4, p. 317-320 4 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
2016

Catalytic Enantioselective Synthesis of N-C Axially Chiral Mebroqualone and Its Derivatives through Reductive Asymmetric Desymmetrization

Hirai, M., Terada, S., Yoshida, H., Ebine, K., Hirata, T. & Kitagawa, O., 2016 Nov 4, In : Organic Letters. 18, 21, p. 5700-5703 4 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)

Catalytic Enantioselective Synthesis of N-C Axially Chiral Phenanthridin-6-one Derivatives

Hirata, T., Takahashi, I., Suzuki, Y., Yoshida, H., Hasegawa, H. & Kitagawa, O., 2016 Jan 4, In : Journal of Organic Chemistry. 81, 1, p. 318-323 6 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)

Chiral additive induced self-disproportionation of enantiomers under MPLC conditions: Preparation of enantiomerically pure samples of 1-(aryl)ethylamines from racemates

Goto, M., Tateishi, K., Ebine, K., Soloshonok, V. A., Roussel, C. & Kitagawa, O., 2016 May 1, In : Tetrahedron Asymmetry. 27, 7-8, p. 317-321 5 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)
2015

A comprehensive examination of the self-disproportionation of enantiomers (SDE) of chiral amides via achiral, laboratory-routine, gravity-driven column chromatography

Suzuki, Y., Han, J., Kitagawa, O., Aceña, J. L., Klika, K. D. & Soloshonok, V. A., 2015, In : RSC Advances. 5, 4, p. 2988-2993 6 p.

Research output: Contribution to journalArticle

38 Citations (Scopus)

Enantioselective synthesis of N-C axially chiral indoles through chiral palladium-catalyzed 5-endo-hydroaminocyclization

Morimoto, Y., Shimizu, S., Mokuya, A., Ototake, N., Saito, A. & Kitagawa, O., 2015 Feb 20, (Accepted/In press) In : Tetrahedron.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Relationship between rotational barriers and structures in N-C axially chiral 3,4-dihydroquinolin-2-one and 3,4-dihydrobenzoquinolin-2-one

Suzuki, Y., Takahashi, I., Dobashi, Y., Hasegawa, H., Roussel, C. & Kitagawa, O., 2015 Jan 1, In : Tetrahedron Letters. 56, 1, p. 132-135 4 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

The synthesis of optically active N-C axially chiral tetrahydroquinoline and its response to an acid-accelerated molecular rotor

Suzuki, Y., Kageyama, M., Morisawa, R., Dobashi, Y., Hasegawa, H., Yokojima, S. & Kitagawa, O., 2015 Jul 18, In : Chemical Communications. 51, 56, p. 11229-11232 4 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)
2014

Asymmetric synthesis of atropisomeric compounds with an N-C chiral axis

Takahashi, I., Suzuki, Y. & Kitagawa, O., 2014 Jan 1, In : Organic Preparations and Procedures International. 46, 1, p. 1-23 23 p.

Research output: Contribution to journalReview article

37 Citations (Scopus)
2013

Chiral initiator-induces self-disproportionation of enantiomers via achiral chromatography: Application to enantiomer separation of racemate

Tateishi, K., Tsukagoshi, S., Nakamura, T., Watanabe, S., Soloshonok, V. A. & Kitagawa, O., 2013 Sep 18, In : Tetrahedron Letters. 54, 38, p. 5220-5223 4 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)

Rotational isomerism in 2,4,6-tri-tert-butylanilides

Ototake, N., Takahashi, I., Tsukagoshi, S., Maeda, T. & Kitagawa, O., 2013 Jan 21, In : Tetrahedron. 69, 3, p. 1013-1016 4 p.

Research output: Contribution to journalArticle

Unique structural properties of 2,4,6-tri-tert-butylanilide: Isomerization and switching between separable amide rotamers through the reaction of anilide enolates

Tsukagoshi, S., Ototake, N., Ohnishi, Y., Shimizu, M. & Kitagawa, O., 2013 May 17, In : Chemistry - A European Journal. 19, 21, p. 6845-6850 6 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)
2012

Catalytic enantioselective synthesis of atropisomeric 2-aryl-4-quinolinone derivatives with an N-C chiral axis

Takahashi, I., Morita, F., Kusagaya, S., Fukaya, H. & Kitagawa, O., 2012 Dec 31, In : Tetrahedron Asymmetry. 23, 24, p. 1657-1662 6 p.

Research output: Contribution to journalArticle

25 Citations (Scopus)

Catalytic enantioselective synthesis of atropisomeric 2-aryl-4-quinolinone derivatives with an N-C chiral axis

Takahashi, I., Morita, F., Kusagaya, S., Fukaya, H. & Kitagawa, O., 2012 Dec 15, In : Tetrahedron: Asymmetry. 23, p. 1657-1662

Research output: Contribution to journalArticle

25 Citations (Scopus)

Catalytic Enantioselective Synthesis of Atropisomeric 4-Quinolinones with an N-C Chiral axis

Takahashi, I., Fumika, F., Morita, M., Izumi, S. & Kitagawa, O., 2012 Oct 30, In : Default journal.

Research output: Contribution to journalArticle

Enantiomer Enrichment of Non-racemic Chiral Amine Derivatives through Achiral Chromatography

Tateishi, K., Nakamura, T., Tsukagoshi, S. & Kitagawa, O., 2012 May 17, In : Default journal.

Research output: Contribution to journalArticle

Reversible Interconversion between Rotational Isomers of 2,4,6-Tri-tert-butylanilides

Tsukagoshi, S., Yusuke, Y., Ohnishi, O. & Kitagawa, O., 2012 Oct 30, In : Default journal.

Research output: Contribution to journalArticle

Self-disproportionation of enantiomers of non-racemic chiral amine derivatives through achiral chromatography

Nakamura, T., Tateishi, K., Tsukagoshi, S., Hashimoto, S., Watanabe, S., Soloshonok, V. A., Aceña, J. L. & Kitagawa, O., 2012 May 27, In : Tetrahedron. 68, 21, p. 4013-4017 5 p.

Research output: Contribution to journalArticle

42 Citations (Scopus)

Self-disproportionation of enantiomers via achiral chromatography: A warning and an extra dimension in optical purifications

Soloshonok, V. A., Roussel, C., Kitagawa, O. & Sorochinskya, A. E., 2012 May 15, In : Chemical Society Reviews. 41, 11, p. 4180-4188 9 p.

Research output: Contribution to journalArticle

111 Citations (Scopus)

Self-disproportionation of enantiomers via achiral chromatography: a warning and an extra dimension in optical purifications

Soloshono, V., Roussel, C., Kitagawa, O., Alex, A. & Sorochinsky, E., 2012 Jun 2, In : Chem. Soc. Rev.. 41, p. 4180-4188

Research output: Contribution to journalArticle

111 Citations (Scopus)

Studies on rotational barriers of N-C axially chiral compounds: Increase in the rotational barrier by aromatization

Suzumura, N., Kageyama, M., Kamimura, D., Inagaki, T., Dobashi, Y., Hasegawa, H., Fukaya, H. & Kitagawa, O., 2012 Aug 15, In : Tetrahedron Letters. 53, 33, p. 4332-4336 5 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Studies on rotational barriers of N-C axially chiral compounds: increase in the rotational barrier by aromatization

Suzumura, N., Kageyama, M., Kamimura, D., Inagak, T., Dobashi, Y., Hasegawa, H., Fukaya, H. & Kitagawa, O., 2012 Aug 1, In : Tetrahedron Lett. 53, p. 4332-4336

Research output: Contribution to journalArticle

10 Citations (Scopus)

Study on Rotational Barrier of N-C Axially Chiral Compounds: Remarkable Increase in the ROtational Barrier by Aromatization

Suzumura, N., Kageyama, M., Dobashi, Y. & Kitagawa, O., 2012 May 17, In : Default journal.

Research output: Contribution to journalArticle

2011
13 Citations (Scopus)

Intramolecular Diels-Alder reaction of N-allyl 2-furoyl amides: Effect of steric strain and amide rotational isomerism

Nakamura, M., Takahashi, I., Yamada, S., Dobashi, Y. & Kitagawa, O., 2011 Jan 5, In : Tetrahedron Letters. 52, 1, p. 53-55 3 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)

Intramolecular Diels-Alder Reaction of N-Allyl 2-Furoyl Amides: Effect of Steric Strain and Amide Rotational Isomerism

Nakamura, M., Takahashi, I., Yamada, S., Dobashi, Y. & Kitagawa, O., 2011 Jan 1, In : Tetrahedron Lett. 52, p. 53-55

Research output: Contribution to journalArticle

19 Citations (Scopus)

Notable structural property of 2,4,6-Tri- tert -butylanilide enolates: Interconversion between the rotamers and their reactivity

Ohnishi, Y., Sakai, M., Nakao, S. & Kitagawa, O., 2011 Jun 3, In : Organic Letters. 13, 11, p. 2840-2843 4 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Notable Structural Property of 2,4,6-Tri-tert-butylanilide Enolates: Interconversion between the Rotamers and Their Reactivity

Ohnishi, Y., Sakai, M., Nakao, S. & Kitagawa, O., 2011 May 20, In : Organic Letters. 13, p. 2840-2843

Research output: Contribution to journalArticle

8 Citations (Scopus)
2010

Atropisomeric lactam chemistry: catalytic enantioselective synthesis, application to asymmetric enolate chemistry and synthesis of key intermediates for NET inhibitors

Takahashi, M., Tanabe, H., Nakamura, T., Kuribara, D., Yamazaki, T. & Kitagawa, O., 2010 Jan 2, In : Tetrahedron. 66, 1, p. 288-296 9 p.

Research output: Contribution to journalArticle

46 Citations (Scopus)

Atropisomeric lactam chemistry: catalytic enantioselective synthesis, application to asymmetric enolate chemistry and synthesis of key intermediates for NET inhibitors

Takahashi, M., Tanabe, H., Nakamura, T., Kuribara, D., Yamazaki, T. & Kitagawa, O., 2010 Jan 5, In : Tetrahedron. 66, p. 288-296

Research output: Contribution to journalArticle

46 Citations (Scopus)

Catalytic enantioselective synthesis of atropisomeric indoles with an N-C chiral axis

Ototake, N., Morimoto, Y., Mokuya, A., Fukaya, H., Shida, Y. & Kitagawa, O., 2010 Jun 18, In : Chemistry - A European Journal. 16, 23, p. 6752-6755 4 p.

Research output: Contribution to journalArticle

52 Citations (Scopus)

Catalytic Enantioselective Synthesis of Atropisomeric Indoles with an N-C Chiral Axis.

Ototake, N., Morimoto, Y., Mokuya, A., Fukaya, H., Shida, Y. & Kitagawa, O., 2010 May 13, In : Chem. Eur. J.. 16, p. 6752-6755

Research output: Contribution to journalArticle

52 Citations (Scopus)
2009

Highly selective stereodivergent synthesis of separable amide rotamers, by using Pd chemistry, and their thermodynamic behavior

Ototake, N., Nakamura, M., Dobashi, Y., Fukaya, H. & Kitagawa, O., 2009 May 11, In : Chemistry - A European Journal. 15, 20, p. 5090-5095 6 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

Highly Selective Stereodivergent Synthesis of Separable Amide Rotamers Using Pd Chemistry and Their Thermodynamic Behaviors.

Ototake, N., Nakamura, M., Dobashi, Y., Fukaya, H. & Kitagawa, O., 2009 May 1, In : Chem. Eur. J.. 15, p. 5090-5095

Research output: Contribution to journalArticle

2008

Catalytic enantioselective synthesis of key intermediates for NET inhibitors using atropisomeric lactam chemistry

Kitagawa, O., Kurihara, D., Tanabe, H., Shibuya, T. & Taguchi, T., 2008 Jan 14, In : Tetrahedron Letters. 49, 3, p. 471-474 4 p.

Research output: Contribution to journalArticle

27 Citations (Scopus)

Stereoselective synthesis of separable amide rotamers using p-allyl-Pd catalyst and their thermodynamic behavior

Ototake, N., Taguchi, T. & Kitagawa, O., 2008 Aug 1, In : Tetrahedron Lett.. 49, p. 5458-5460

Research output: Contribution to journalArticle

Stereoselective synthesis of separable amide rotamers using π-allyl-Pd catalyst and their thermodynamic behavior

Ototake, N., Taguchi, T. & Kitagawa, O., 2008 Sep 15, In : Tetrahedron Letters. 49, 38, p. 5458-5460 3 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)
2007

Highly Enantioselctive Synthesis of Atropisomeric Lactams through Catalytic Asymmetric Buchwald-Hartwig Amination

Kitagawa, O., Tanabe, H. & Taguchi, T., 2007 Aug 23, In : Default journal.

Research output: Contribution to journalArticle

2006
18 Citations (Scopus)