• 5407 Citations
  • 40 h-Index
19942019

Research output per year

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Research Output

  • 5407 Citations
  • 40 h-Index
  • 127 Article
  • 1 Comment/debate
  • 1 Review article
2000

A concise and efficient route to 2α-(ω-hydroxyalkoxy)-1α,25-dihydroxyvitamin D3: Remarkably high affinity to vitamin D receptor

Kittaka, A., Suhara, Y., Takayanagi, H., Fujishima, T., Kurihara, M. & Takayama, H., 2000 Aug 24, In : Organic Letters. 2, 17, p. 2619-2622 4 p.

Research output: Contribution to journalArticle

80 Citations (Scopus)

Efficient Synthesis and Biological Evaluation of Novel 2α-Substituted 1α,25-Dihydroxy- vitamin D3 Analogues: Remarkable Potency for Calcium-Regulating Effect

SUHARA, SUHARA., Y., Y., NIHEI, NIHEI., K., K., TANIGAWA, TANIGAWA., H., H., FUJISHIMA, FUJISHIMA., T., T., KONNO, KONNO., NAKAGAWA, NAKAGAWA., OKANO, OKANO., KURIHARA, KURIHARA., M., M. & TAKAYAMA, TAKAYAMA., 2000 Sep 1, In : Proceeding of the 10th Vitamin D Workshop.

Research output: Contribution to journalArticle

Evidence that 2-arachidonoylglycerol but not N-palmitoylethanolamine or anandamide is the physiological ligand for the cannabinoid CB2 receptor. Comparison of the agonistic activities of various cannabinoid receptor ligands in HL-60 cells

Sugiura, T., Kondo, S., Kishimoto, S., Miyashita, T., Nakane, S., Kodaka, T., Suhara, Y., Takayama, H. & Waku, K., 2000 Jan 7, In : Journal of Biological Chemistry. 275, 1, p. 605-612 8 p.

Research output: Contribution to journalArticle

300 Citations (Scopus)

Evidence that 2-Arachidonoylglycerol but Not N-Palmitoylethanolamine or Anandamide Is the Physiological Ligand for the Cannnabinoid CB2 Receptor

SUGIURA, SUGIURA., T., T., KONDO, KONDO., S., S., KISHIMOTO, KISHIMOTO., MIYASHITA, MIYASHITA., NAKANE, NAKANE., KODAKA, KODAKA., SUHARA, SUHARA., Y., Y., TAKAYAMA, TAKAYAMA., H., H., WAKU, WAKU. & K., K., 2000 Jan 1, In : Journal of Biological Chemistry. 275, p. 605-612

Research output: Contribution to journalArticle

300 Citations (Scopus)

Facile Synthesis of 2 -(Hydroxyalkoxy)-1 ,25-dihydroxyvitamin D

KITTAKA, KITTAKA., A., A., SUHARA, SUHARA., Y., Y., H., TAKAYANAGI., FUJISHIMA, FUJISHIMA., T., T., KURIHARA, KURIHARA., M., M., TAKAYAMA, TAKAYAMA. & H., H., 2000 Sep 1, In : Proceeding of the 10th Vitamin D Workshop.

Research output: Contribution to journalArticle

Syntheses and biological evaluation of novel 2α-substituted 1α,25-dihydroxyvitamin D3 analogues

Suhara, Y., Nihei, K. I., Tanigawa, H., Fujishima, T., Konno, K., Nakagawa, K., Okano, T. & Takayama, H., 2000 May 15, In : Bioorganic and Medicinal Chemistry Letters. 10, 10, p. 1129-1132 4 p.

Research output: Contribution to journalArticle

64 Citations (Scopus)

Synthesis and Biological Activities of 2-Arachidonoylglycerol, an Endogenous Cannabinoid Receptor Ligand, and Its Metabolically Stable Ether-linked Analogues

SUHARA, SUHARA., Y., Y., TAKAYAMA, TAKAYAMA., H., H., NAKANE, NAKANE., S.:MIYASHITA, S. MIYASHITA., T., T., WAKU, WAKU., K., K. & SUGIURA, SUGIURA., 2000 Jun 1, In : Chemical & Pharmaceutical Bulletin. 48, p. 903-907

Research output: Contribution to journalArticle

34 Citations (Scopus)

Synthesis and biological activities of 2- arachidonoylglycerol, an endogenous cannabinoid receptor ligand, and its metabolically stable ether-linked analogues

Suhara, Y., Takayama, H., Nakane, S., Miyashita, T., Waku, K. & Sugiura, T., 2000 Jul, In : Chemical and Pharmaceutical Bulletin. 48, 7, p. 903-907 5 p.

Research output: Contribution to journalArticle

34 Citations (Scopus)

Synthesis and Biological Evaluation of Novel 2 alfa-Substituted 1alpa,25-Dihydroxyvitamin D3 Analogues

SUHARA, SUHARA., Y., Y., NIHEI, NIHEI., K., K., TANIGAWA, TANIGAWA., H., H., FUJISHIMA, FUJISHIMA., T., T., KONNO, KONNO., NAKAGAWA, NAKAGAWA., OKANO, OKANO. & TAKAYAMA, TAKAYAMA., 2000 Jun 1, In : Bioorganic & Medicinal Chemistry Letters. 10, p. 1129-1132

Research output: Contribution to journalArticle

64 Citations (Scopus)
1999

Evidence that the cannabinoid CB1 receptor is a 2-arachidonoylglycerol receptor: Structure-activity relationship of 2-arachidonoylglycerol, ether- linked analogues, and related compounds

Sugiura, T., Kodaka, T., Nakane, S., Miyashita, T., Kondo, S., Suhara, Y., Takayama, H., Waku, K., Seki, C., Baba, N. & Ishima, Y., 1999 Jan 29, In : Journal of Biological Chemistry. 274, 5, p. 2794-2801 8 p.

Research output: Contribution to journalArticle

252 Citations (Scopus)

Evidence that the Cannabinoid CB1 Receptor Is a 2-Arachidonoylglycerol Receptor

SUGIURA, SUGIURA., T., T., KODAKA, KODAKA., NAKANE, NAKANE., S.:MIYASHITA, S. MIYASHITA., KONDO, KONDO., S., S., SUHARA, SUHARA., Y., Y., TAKAYAMA, TAKAYAMA., H., H., WAKU, WAKU., K., K., SEKI, SEKI., C., C., BABA, BABA., N., N. & Y., ISHIMA., 1999 Jan 1, In : Journal of Biological Chemistry. 274, p. 2794-2801

Research output: Contribution to journalArticle

252 Citations (Scopus)
1998

1-N-Iminosugars: Potent and selective inhibitors of β-glycosidases

Ichikawa, Y., Igarashi, Y., Ichikawa, M. & Suhara, Y., 1998 Apr 8, In : Journal of the American Chemical Society. 120, 13, p. 3007-3018 12 p.

Research output: Contribution to journalArticle

210 Citations (Scopus)

1-N-Iminosugars: Potent and Selective Inhibitors of beta -Glycosidases

ICHIKAWA, ICHIKAWA., Y., Y., IGARASHI, IGARASHI., M., M. & SUHARA, SUHARA., 1998 Mar 1, In : Journal of American Chmeical Society. 120, p. 3007-3018

Research output: Contribution to journalArticle

210 Citations (Scopus)

Development of a Stereoselective C-glycosylation and Glycamino Acid-Based New Carbohydrate Analog

Suhara, Y., Igarashi, Y., Ichikawa, M., Izumi, M. & Ichikawa, Y., 1998, In : Yuki Gosei Kagaku Kyokaishi/Journal of Synthetic Organic Chemistry. 56, 7, p. 557-566 10 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Erratum: 1-N-Iminosugars: Potent and selective inhibitors of β- glycosidases (Journal of American Chemical Society (1998) 120 (3007-3018))

Ichikawa, Y., Igarashi, Y., Ichikawa, M. & Suhara, Y., 1998 Jun 17, In : Journal of the American Chemical Society. 120, 23, p. 5854 1 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)
1997

Peptide-Sugar Hybrid: Like Peptide, Like Oligosaccharide

SUHARA, SUHARA., Y., Y., IZUMI, IZUMI., M., M., ICHIKAWA, ICHIKAWA., PENNO, PENNO. & M.B., M. B., 1997 Nov 1, In : Tetrahedron Letters. 38, p. 7167-7170

Research output: Contribution to journalArticle

26 Citations (Scopus)

Peptide-sugar hybrids: Like peptide, like oligosaccharide

Suhara, Y., Izumi, M., Ichikawa, M., Penno, M. B. & Ichikawa, Y., 1997 Oct 13, In : Tetrahedron Letters. 38, 41, p. 7167-7170 4 p.

Research output: Contribution to journalArticle

26 Citations (Scopus)
1996

Comparison of the biological activity of synthetic N-acylated asparagine or serine linked monosaccharide lipid A analogs

Shimizu, T., Iwamoto, Y., Yanagihara, Y., Ryoyama, K., Suhara, Y., Ikeda, K. & Achiwa, K., 1996, In : Immunobiology. 196, 4, p. 321-331 11 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Comparison of the Biological Activity of Synthetic N-Acylated Asparagine or Serine Linked Monosaccharide Lipid A Analogues

SHIMIZU, SHIMIZU., T., T., IWAMOTO, IWAMOTO., Y., Y., YANAGIHARA, YANAGIHARA., RYOYAMA, RYOYAMA., K., K., SUHARA, SUHARA., IKEDA, IKEDA. & ACHIWA, ACHIWA., 1996 Mar 1, In : Immunobiology. 196, p. 321-331

Research output: Contribution to journalArticle

Synthesis of a New Carbohydrate Mimetics: "Carbopeptoid" Containing a C-1 Carboxylate and C-2 Amino Group

SUHARA, SUHARA., Y., Y., HILDRETH, HILDRETH., K., J. E. & ICHIKAWA, ICHIKAWA., 1996 Mar 1, In : Tetrahedron Letters. 37, p. 1575-1578

Research output: Contribution to journalArticle

80 Citations (Scopus)

Synthesis of a new carbohydrate mimetics "carbopeptoid"

SUHARA, SUHARA., Y., Y. & ICHIKAWA, ICHIKAWA., 1996 Mar 24, In : Book of Abstracts, 211th ACS National Meeting.

Research output: Contribution to journalArticle

Synthesis of Sulfated beta-1,6-Linked Oligosaccharide Mimetics: A Novel Potent Inhibitor of HIV Replication

SUHARA, SUHARA., Y., Y., ICHIKAWA, ICHIKAWA., M., M., HILDRETH, HILDRETH. & K., J. E., 1996 Apr 1, In : Tetrahedron Letters. 37, p. 2459-2552

Research output: Contribution to journalArticle

52 Citations (Scopus)

Synthesis of sulfated β-1,6-linked oligosaccharide mimetics: A novel potent inhibitor of HIV replication

Suhara, Y., Ichikawa, M., Hildreth, J. E. K. & Ichikawa, Y., 1996 Apr 8, In : Tetrahedron Letters. 37, 15, p. 2549-2552 4 p.

Research output: Contribution to journalArticle

60 Citations (Scopus)
1995
10 Citations (Scopus)
1994

Lipid A and Related Compounds. XXIX.: Synthesis of Biologically Active N-Acylated L-Asparagine-Containing D-Glucosamine Derivatives Structually Related to Lipid A

SUHARA, SUHARA., Y., Y., ARAKAWA, ARAKAWA., M., M., IKEDA, IKEDA., K., K. & ACHIWA, ACHIWA., 1994 Dec 1, In : Chemical & Pharmaceutical Bulletin. 42, p. 2526-2531

Research output: Contribution to journalArticle

10 Citations (Scopus)

Protective Effect of Sodium L-Malate, an Active Constituent Isolated from Angelicae Radix, on cis-Diamminedichloroplatinum (II)-Induced Toxic Side Effect

SUGIYAMA, SUGIYAMA., K., K., UEDA, UEDA., H., H., SUHARA, SUHARA., Y., Y., KAJIMA, KAJIMA., ICHIO, ICHIO., YOKOTA, YOKOTA. & M., M., 1994 Dec 1, In : Chemical & Pharmaceutical Bulletin. 42, p. 2565-2568

Research output: Contribution to journalArticle

9 Citations (Scopus)