Find Research outputs

2013

Cacao Polyphenols Influence the Regulation of Apolipoproteins

Osakabe, N., 2013 Nov, Polyphenols in the Prevention and Treatment of Vascular and Cardiac Disease, and Cancer. Elsevier Inc., Vol. 2. p. 963-970 8 p.

Research output: Chapter in Book/Report/Conference proceeding › Chapter

2011

Polyphenols in Theobroma Cacao ameliorate microcirculation.:in vivo intravital microscopic observation in rats.

Shibata, M. & Osakabe, N., 2011 Oct 18, In: ５th　International conference on food factors.

Research output: Contribution to journal › Article › peer-review

2018

Eldecalcitol is more effective in promoting osteogenesis than alfacalcidol in Cyp27b1-knockout mice

HirotaI, Y., Nakagawa, K., Isomoto, K., Sakaki, T., Kubodera, N., Kamao, M., Osakabe, N., Suhara, Y. & Okano, T., 2018 Oct, In: PLoS ONE. 13, 10, e0199856.

Research output: Contribution to journal › Article › peer-review

1 Citation (Scopus)

2015

A single oral administration of theaflavins increases energy expenditure and the expression of metabolic genes

Kudo, N., Arai, Y., Suhara, Y., Ishii, T., Nakayama, T. & Osakabe, N., 2015 Sep 16, In: PLoS ONE. 10, 9, e0137809.

Research output: Contribution to journal › Article › peer-review

25 Citations (Scopus)

2019

Simultaneous electrochemical determination of isoquercitrin and epigallocatechingallate at a carbon nanotube electrode

Takahashi, S., Muguruma, H., Osakabe, N., Inoue, H. & Ohsawa, T., 2019, In: Electrochemistry. 87, 4, p. 242-244 3 p.

Research output: Contribution to journal › Article › peer-review

Open Access

2 Citations (Scopus)

Synthesis and in vitro evaluation of novel liver X receptor agonists based on naphthoquinone derivatives

Nishioka, T., Endo-Umeda, K., Ito, Y., Shimoda, A., Takeuchi, A., Tode, C., Hirota, Y., Osakabe, N., Makishima, M. & Suhara, Y., 2019 Nov 26, In: Molecules. 24, 23, 4316.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Citation (Scopus)

2017

Synthesis of Novel Synthetic Vitamin K Analogues Prepared by Introduction of a Heteroatom and a Phenyl Group That Induce Highly Selective Neuronal Differentiation of Neuronal Progenitor Cells

Kimura, K., Hirota, Y., Kuwahara, S., Takeuchi, A., Tode, C., Wada, A., Osakabe, N. & Suhara, Y., 2017 Mar 23, In: Journal of Medicinal Chemistry. 60, 6, p. 2591-2596 6 p.

Research output: Contribution to journal › Article › peer-review

10 Citations (Scopus)

2018

Green tea extract and black tea extract differentially influence cecal levels of short-chain fatty acids in rats

Unno, T. & Osakabe, N., 2018 Jun, In: Food Science and Nutrition. 6, 4, p. 728-735 8 p.

Research output: Contribution to journal › Article › peer-review

11 Citations (Scopus)

Single oral administration of flavan 3-ols induces stress responses monitored with stress hormone elevations in the plasma and paraventricular nucleus

Fujii, Y., Suzuki, K., Hasegawa, Y., Nanba, F., Toda, T., Adachi, T., Taira, S. & Osakabe, N., 2018 Aug 24, In: Neuroscience Letters. 682, p. 106-111 6 p.

Research output: Contribution to journal › Article › peer-review

5 Citations (Scopus)

2013

Flavan 3-ols improve metabolic syndrome risk factors: Evidence and mechanisms

Osakabe, N., 2013 May, In: Journal of Clinical Biochemistry and Nutrition. 52, 3, p. 186-192 7 p.

Research output: Contribution to journal › Review article › peer-review

29 Citations (Scopus)

2012

Polyphenols in Theobroma Cacao ameliorate microcirculation: In vivo intravital microscopic observation in rats

Osakabe, N., 2012 Apr 1, In: Journal of Food and Drug Analysis. 20, SUPPL.1, p. 288-291 4 p.

Research output: Contribution to journal › Article › peer-review

1 Citation (Scopus)

2019

Corticotropinreleasing hormone is significantly upregulated in the mouse paraventricular nucleus following a single oral dose of cinnamtannin A2 as an (−)epicatechin tetramer

Fujii, Y., Suzuki, K., Adachi, T., Taira, S. & Osakabe, N., 2019, In: Journal of Clinical Biochemistry and Nutrition. 65, 4, p. 29-33 5 p.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Citation (Scopus)

2016

Visualization of probiotic-mediated Ca²⁺ signaling in intestinal epithelial cells in vivo

Adachi, T., Kakuta, S., Aihara, Y., Kamiya, T., Watanabe, Y., Osakabe, N., Hazato, N., Miyawaki, A., Yoshikawa, S., Usami, T., Karasuyama, H., Kimoto-Nira, H., Hirayama, K. & Tsuji, N. M., 2016, In: Frontiers in Immunology. 7, DEC, 601.

Research output: Contribution to journal › Article › peer-review

14 Citations (Scopus)

2012

Ingestion of cocoa ameliorates endothelial dysfunction in mesentery arterioles induced by high fat diet in rats: An in vivo intravital microscopy study

Osakabe, N. & Shibata, M., 2012 Dec 10, In: Life Sciences. 91, 23-24, p. 1196-1200 5 p.

Research output: Contribution to journal › Article › peer-review

4 Citations (Scopus)

2011

Amelioration of flavan 3-ols on microcirculation in rat cremaster muscle and mesentery evaluated by in vivo intravital microscopic technique

Shibata, M. & Osakabe, N., 2011 Oct 19, In: 5th　International conference of polyphenol and health.

Research output: Contribution to journal › Article › peer-review

2017

Flavan 3-ol delays the progression of disuse atrophy induced by hindlimb suspension in mice

Ito, M., Kudo, N., Miyake, Y., Imai, T., Unno, T., Yamashita, Y., Hirota, Y., Ashida, H. & Osakabe, N., 2017 Nov, In: Experimental Gerontology. 98, p. 120-123 4 p.

Research output: Contribution to journal › Article › peer-review

4 Citations (Scopus)

2018

Comparison of the sympathetic stimulatory abilities of B-type procyanidins based on induction of uncoupling protein-1 in brown adipose tissue (BAT) and increased plasma catecholamine (CA) in mice

Nakagawa, Y., Ishimura, K., Oya, S., Kamino, M., Fujii, Y., Nanba, F., Toda, T., Ishii, T., Adachi, T., Suhara, Y. & Osakabe, N., 2018 Jul, In: PLoS ONE. 13, 7, e0201203.

Research output: Contribution to journal › Article › peer-review

8 Citations (Scopus)

2019

Polyphenol analysis in black tea with a carbon nanotube electrode

Murakami, S., Takahashi, S., Muguruma, H., Osakabe, N., Inoue, H. & Ohsawa, T., 2019, In: Analytical Sciences. 35, 5, p. 529-534 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

4 Citations (Scopus)

2017

Substitution at the C-3 position of catechins has an influence on the binding affinities against serum albumin

Ikeda, M., Ueda-Wakagi, M., Hayashibara, K., Kitano, R., Kawase, M., Kaihatsu, K., Kato, N., Suhara, Y., Osakabe, N. & Ashida, H., 2017 Feb 1, In: Molecules. 22, 2, 314.

Research output: Contribution to journal › Article › peer-review

8 Citations (Scopus)

2019

Elucidation of the interaction between flavan-3-ols and bovine serum albumin and its effect on their in-vitro cytotoxicity

Fujii, Y., Suhara, Y., Sukikara, Y., Teshima, T., Hirota, Y., Yoshimura, K. & Osakabe, N., 2019 Oct 11, In: Molecules. 24, 20, 3667.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Citation (Scopus)

Separationless and Adsorptionless Quantification of Individual Catechins in Green Tea with a Carbon Nanotube-Carboxymethylcellulose Electrode

Muguruma, H., Murakami, S., Takahashi, S., Osakabe, N., Inoue, H. & Ohsawa, T., 2019 Jan 23, In: Journal of Agricultural and Food Chemistry. 67, 3, p. 943-954 12 p.

Research output: Contribution to journal › Article › peer-review

10 Citations (Scopus)

2018

Possible mechanisms of postprandial physiological alterations following flavan 3-ol ingestion

Osakabe, N. & Terao, J., 2018 Mar 1, In: Nutrition Reviews. 76, 3, p. 174-186 13 p.

Research output: Contribution to journal › Article › peer-review

7 Citations (Scopus)

2019

Electrochemical determination with a long-length carbon nanotube electrode of quercetin glucosides in onion, apple peel, and tartary buckwheat

Takahashi, S., Muguruma, H., Osakabe, N., Inoue, H. & Ohsawa, T., 2019 Dec 1, In: Food Chemistry. 300, 125189.

Research output: Contribution to journal › Article › peer-review

7 Citations (Scopus)

Acylated anthocyanins derived from purple carrot (: Daucus carota L.) induce elevation of blood flow in rat cremaster arteriole

Tsutsumi, A., Horikoshi, Y., Fushimi, T., Saito, A., Koizumi, R., Fujii, Y., Hu, Q. Q., Hirota, Y., Aizawa, K. & Osakabe, N., 2019 Mar, In: Food and Function. 10, 3, p. 1726-1735 10 p.

Research output: Contribution to journal › Article › peer-review

10 Citations (Scopus)

2016

Onset of a hypotensive effect following ingestion of flavan 3-ols involved in the activation of adrenergic receptors

Saito, A., Inagawa, K., Ebe, R., Fukase, S., Horikoshi, Y., Shibata, M. & Osakabe, N., 2016 Oct 1, In: Free Radical Biology and Medicine. 99, p. 584-592 9 p.

Research output: Contribution to journal › Article › peer-review

6 Citations (Scopus)

A single oral dose of flavan-3-ols enhances energy expenditure by sympathetic nerve stimulation in mice

Kamio, N., Suzuki, T., Watanabe, Y., Suhara, Y. & Osakabe, N., 2016 Feb 1, In: Free Radical Biology and Medicine. 91, p. 256-263 8 p.

Research output: Contribution to journal › Article › peer-review

20 Citations (Scopus)

2011

Cacao polyphenols influence the regulation of apolipoprotein in hepg2 and caco2 cells

Yasuda, A., Natsume, M., Osakabe, N., Kawahata, K. & Koga, J., 2011 Feb 23, In: Journal of Agricultural and Food Chemistry. 59, 4, p. 1470-1476 7 p.

Research output: Contribution to journal › Article › peer-review

34 Citations (Scopus)

2016

The impact of theaflavins on systemic-and microcirculation alterations: The murine and randomized feasibility trials

Saito, A., Nakazato, R., Suhara, Y., Shibata, M., Fukui, T., Ishii, T., Asanuma, T., Mochizuki, K., Nakayama, T. & Osakabe, N., 2016 Jun 1, In: Journal of Nutritional Biochemistry. 32, p. 107-114 8 p.

Research output: Contribution to journal › Article › peer-review

13 Citations (Scopus)

Catecholamines Facilitate Fuel Expenditure and Protect Against Obesity via a Novel Network of the Gut-Brain Axis in Transcription Factor Skn-1-deficient Mice

Ushiama, S., Ishimaru, Y., Narukawa, M., Yoshioka, M., Kozuka, C., Watanabe, N., Tsunoda, M., Osakabe, N., Asakura, T., Masuzaki, H. & Abe, K., 2016 Jun 1, In: EBioMedicine. 8, p. 60-71 12 p.

Research output: Contribution to journal › Article › peer-review

14 Citations (Scopus)

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