A facile α-iodination reaction of unsaturated amides

Osamu Kitagawa; Tokushi Hanano; Tatsuya Hirata; Tadashi Inoue; Takeo Taguchi

doi:10.1016/S0040-4039(00)91606-X

A facile α-iodination reaction of unsaturated amides

Osamu Kitagawa, Tokushi Hanano, Tatsuya Hirata, Tadashi Inoue, Takeo Taguchi

Research output: Contribution to journal › Article › peer-review

23 Citations (Scopus)

Abstract

A novel and mild α-iodination of carboxamides was developed. Unsaturated amides could be converted to the α-iodoamides in moderate to good yields by treatment with I₂ in the presence of s-collidine.

Original language	English
Pages (from-to)	1299-1302
Number of pages	4
Journal	Tetrahedron Letters
Volume	33
Issue number	10
DOIs	https://doi.org/10.1016/S0040-4039(00)91606-X
Publication status	Published - 1992 Mar 3
Externally published	Yes

Keywords

collidine
imidate
iodination
iodine
unsaturated amide

ASJC Scopus subject areas

Biochemistry
Drug Discovery
Organic Chemistry

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10.1016/S0040-4039(00)91606-X

Cite this

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title = "A facile α-iodination reaction of unsaturated amides",

abstract = "A novel and mild α-iodination of carboxamides was developed. Unsaturated amides could be converted to the α-iodoamides in moderate to good yields by treatment with I2 in the presence of s-collidine.",

keywords = "collidine, imidate, iodination, iodine, unsaturated amide",

author = "Osamu Kitagawa and Tokushi Hanano and Tatsuya Hirata and Tadashi Inoue and Takeo Taguchi",

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T1 - A facile α-iodination reaction of unsaturated amides

AU - Kitagawa, Osamu

AU - Hanano, Tokushi

AU - Hirata, Tatsuya

AU - Inoue, Tadashi

AU - Taguchi, Takeo

PY - 1992/3/3

Y1 - 1992/3/3

N2 - A novel and mild α-iodination of carboxamides was developed. Unsaturated amides could be converted to the α-iodoamides in moderate to good yields by treatment with I2 in the presence of s-collidine.

AB - A novel and mild α-iodination of carboxamides was developed. Unsaturated amides could be converted to the α-iodoamides in moderate to good yields by treatment with I2 in the presence of s-collidine.

KW - collidine

KW - imidate

KW - iodination

KW - iodine

KW - unsaturated amide

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EP - 1302

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 10

ER -

A facile α-iodination reaction of unsaturated amides

Abstract

Keywords

ASJC Scopus subject areas

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