A facile α-iodination reaction of unsaturated amides

Osamu Kitagawa, Tokushi Hanano, Tatsuya Hirata, Tadashi Inoue, Takeo Taguchi

Research output: Contribution to journalArticle

23 Citations (Scopus)

Abstract

A novel and mild α-iodination of carboxamides was developed. Unsaturated amides could be converted to the α-iodoamides in moderate to good yields by treatment with I2 in the presence of s-collidine.

Original languageEnglish
Pages (from-to)1299-1302
Number of pages4
JournalTetrahedron Letters
Volume33
Issue number10
DOIs
Publication statusPublished - 1992 Mar 3
Externally publishedYes

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Amides
gamma-collidine

Keywords

  • collidine
  • imidate
  • iodination
  • iodine
  • unsaturated amide

ASJC Scopus subject areas

  • Biochemistry
  • Organic Chemistry
  • Drug Discovery

Cite this

A facile α-iodination reaction of unsaturated amides. / Kitagawa, Osamu; Hanano, Tokushi; Hirata, Tatsuya; Inoue, Tadashi; Taguchi, Takeo.

In: Tetrahedron Letters, Vol. 33, No. 10, 03.03.1992, p. 1299-1302.

Research output: Contribution to journalArticle

Kitagawa, O, Hanano, T, Hirata, T, Inoue, T & Taguchi, T 1992, 'A facile α-iodination reaction of unsaturated amides', Tetrahedron Letters, vol. 33, no. 10, pp. 1299-1302. https://doi.org/10.1016/S0040-4039(00)91606-X
Kitagawa, Osamu ; Hanano, Tokushi ; Hirata, Tatsuya ; Inoue, Tadashi ; Taguchi, Takeo. / A facile α-iodination reaction of unsaturated amides. In: Tetrahedron Letters. 1992 ; Vol. 33, No. 10. pp. 1299-1302.
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