A microfluidic static gradient generator using limited diffusuon through T-shaped narrow channels

Makoto Tamura; Shugo Maeda; Tomohisa Ogawa; Masato Tanaka; Nobuyuki Futai

doi:10.1109/MHS.2014.7006121

A microfluidic static gradient generator using limited diffusuon through T-shaped narrow channels

Makoto Tamura, Shugo Maeda, Tomohisa Ogawa, Masato Tanaka, Nobuyuki Futai

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

1 Citation (Scopus)

Abstract

We have developed a poly (dimethylsiloxane) (PDMS)-cast microfluidic chip that contains a thin (cross-sectional area less than 1.0 μm2) but high aspect ratio (1:1 ∼ 1:3) microchannels. Experimental results showed that the gradient of an example of test substances (sodium fluorescein) remained constant in the thin channel over a long period of time (30 minutes) by simple manual liquid handling. We aim to develop a thinner channel keeping the gradient longer time.

Original language	English
Title of host publication	2014 International Symposium on Micro-NanoMechatronics and Human Science, MHS 2014
Publisher	Institute of Electrical and Electronics Engineers Inc.
ISBN (Electronic)	9781479966790
DOIs	https://doi.org/10.1109/MHS.2014.7006121
Publication status	Published - 2015 Jan 9
Event	2014 International Symposium on Micro-NanoMechatronics and Human Science, MHS 2014 - Nagoya, Japan Duration: 2014 Nov 10 → 2014 Nov 12

Other

Other	2014 International Symposium on Micro-NanoMechatronics and Human Science, MHS 2014
Country/Territory	Japan
City	Nagoya
Period	14/11/10 → 14/11/12

ASJC Scopus subject areas

Electrical and Electronic Engineering
Mechanical Engineering

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10.1109/MHS.2014.7006121

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A microfluidic static gradient generator using limited diffusuon through T-shaped narrow channels. / Tamura, Makoto; Maeda, Shugo; Ogawa, Tomohisa; Tanaka, Masato; Futai, Nobuyuki.

2014 International Symposium on Micro-NanoMechatronics and Human Science, MHS 2014. Institute of Electrical and Electronics Engineers Inc., 2015. 7006121.

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Tamura, M, Maeda, S, Ogawa, T, Tanaka, M & Futai, N 2015, A microfluidic static gradient generator using limited diffusuon through T-shaped narrow channels. in 2014 International Symposium on Micro-NanoMechatronics and Human Science, MHS 2014., 7006121, Institute of Electrical and Electronics Engineers Inc., 2014 International Symposium on Micro-NanoMechatronics and Human Science, MHS 2014, Nagoya, Japan, 14/11/10. https://doi.org/10.1109/MHS.2014.7006121

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AU - Futai, Nobuyuki

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AB - We have developed a poly (dimethylsiloxane) (PDMS)-cast microfluidic chip that contains a thin (cross-sectional area less than 1.0 μm2) but high aspect ratio (1:1 ∼ 1:3) microchannels. Experimental results showed that the gradient of an example of test substances (sodium fluorescein) remained constant in the thin channel over a long period of time (30 minutes) by simple manual liquid handling. We aim to develop a thinner channel keeping the gradient longer time.

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PB - Institute of Electrical and Electronics Engineers Inc.

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Y2 - 10 November 2014 through 12 November 2014

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A microfluidic static gradient generator using limited diffusuon through T-shaped narrow channels

Abstract

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