A mild and environmentally benign oxidation of thiols to disulfides

Masayuki Kirihara, Yasutaka Asai, Shiho Ogawa, Takuya Noguchi, Akihiko Hatano, Yoshiro Hirai

Research output: Contribution to journalArticle

144 Citations (Scopus)

Abstract

Thiols were effectively oxidized into disulfides by reacting with hydrogen peroxide in the presence of a catalytic amount of iodide ion or iodine.

Original languageEnglish
Article numberF15107SS
Pages (from-to)3286-3289
Number of pages4
JournalSynthesis
Issue number21
DOIs
Publication statusPublished - 2007 Nov 2
Externally publishedYes

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Keywords

  • Disulfide
  • Hydrogen peroxide
  • Iodide catalyst
  • Oxidative coupling
  • Thiol

ASJC Scopus subject areas

  • Organic Chemistry

Cite this

Kirihara, M., Asai, Y., Ogawa, S., Noguchi, T., Hatano, A., & Hirai, Y. (2007). A mild and environmentally benign oxidation of thiols to disulfides. Synthesis, (21), 3286-3289. [F15107SS]. https://doi.org/10.1055/s-2007-990800