A Thin-Film Glucose Biosensor Based on Hexamethyldisiloxane Plasma-Polymerized Film

Influence of Its Film Thickness on the Platinum Electrode

Yoshihiro Kase, Hitoshi Muguruma, Atsunori Hiratsuka, Isao Karube

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

An amperometric thin-film glucose biosensor based on a plasma-polymerized film using hexamethyldisiloxane as the monomer is presented. The plasma-polymerized film, achieved in plasma in the vapor phase, offers a new alternative for use in the design of the electrode-enzyme interface of biosensors. The film shows promise of high sensor performance; namely, rapid sensor response, low noise, a wide dynamic range, reproducibility, and reduction in the effects of interfering materials such as ascorbic acid. In this study, we examined the usefulness of the hexamethyl-disiloxane plasma-polymerized film and investigated how the thickness of the plasma-polymerized film on a platinum electrode affected sensor characteristics: the selectivity for hydrogen peroxide versus interfering agents, the sensor response due to enzymatic reaction, and oxygen depletion.

Original languageEnglish
Pages (from-to)142-147
Number of pages6
JournalIEICE Transactions on Electronics
VolumeE87-C
Issue number2
Publication statusPublished - 2004 Feb

Fingerprint

Platinum
Biosensors
Glucose
Film thickness
Plasmas
Thin films
Electrodes
Sensors
Enzyme electrodes
Ascorbic acid
Hydrogen peroxide
Hydrogen Peroxide
Ascorbic Acid
Monomers
Vapors
hexamethyldisiloxane
Oxygen

Keywords

  • Biosensor
  • Enzyme
  • Glucose
  • Hexamethyldisiloxane
  • Plasma-polymerized film

ASJC Scopus subject areas

  • Electrical and Electronic Engineering

Cite this

A Thin-Film Glucose Biosensor Based on Hexamethyldisiloxane Plasma-Polymerized Film : Influence of Its Film Thickness on the Platinum Electrode. / Kase, Yoshihiro; Muguruma, Hitoshi; Hiratsuka, Atsunori; Karube, Isao.

In: IEICE Transactions on Electronics, Vol. E87-C, No. 2, 02.2004, p. 142-147.

Research output: Contribution to journalArticle

@article{dff7ad070ec64d11a63da9a1bd456bf7,
title = "A Thin-Film Glucose Biosensor Based on Hexamethyldisiloxane Plasma-Polymerized Film: Influence of Its Film Thickness on the Platinum Electrode",
abstract = "An amperometric thin-film glucose biosensor based on a plasma-polymerized film using hexamethyldisiloxane as the monomer is presented. The plasma-polymerized film, achieved in plasma in the vapor phase, offers a new alternative for use in the design of the electrode-enzyme interface of biosensors. The film shows promise of high sensor performance; namely, rapid sensor response, low noise, a wide dynamic range, reproducibility, and reduction in the effects of interfering materials such as ascorbic acid. In this study, we examined the usefulness of the hexamethyl-disiloxane plasma-polymerized film and investigated how the thickness of the plasma-polymerized film on a platinum electrode affected sensor characteristics: the selectivity for hydrogen peroxide versus interfering agents, the sensor response due to enzymatic reaction, and oxygen depletion.",
keywords = "Biosensor, Enzyme, Glucose, Hexamethyldisiloxane, Plasma-polymerized film",
author = "Yoshihiro Kase and Hitoshi Muguruma and Atsunori Hiratsuka and Isao Karube",
year = "2004",
month = "2",
language = "English",
volume = "E87-C",
pages = "142--147",
journal = "IEICE Transactions on Electronics",
issn = "0916-8524",
publisher = "Maruzen Co., Ltd/Maruzen Kabushikikaisha",
number = "2",

}

TY - JOUR

T1 - A Thin-Film Glucose Biosensor Based on Hexamethyldisiloxane Plasma-Polymerized Film

T2 - Influence of Its Film Thickness on the Platinum Electrode

AU - Kase, Yoshihiro

AU - Muguruma, Hitoshi

AU - Hiratsuka, Atsunori

AU - Karube, Isao

PY - 2004/2

Y1 - 2004/2

N2 - An amperometric thin-film glucose biosensor based on a plasma-polymerized film using hexamethyldisiloxane as the monomer is presented. The plasma-polymerized film, achieved in plasma in the vapor phase, offers a new alternative for use in the design of the electrode-enzyme interface of biosensors. The film shows promise of high sensor performance; namely, rapid sensor response, low noise, a wide dynamic range, reproducibility, and reduction in the effects of interfering materials such as ascorbic acid. In this study, we examined the usefulness of the hexamethyl-disiloxane plasma-polymerized film and investigated how the thickness of the plasma-polymerized film on a platinum electrode affected sensor characteristics: the selectivity for hydrogen peroxide versus interfering agents, the sensor response due to enzymatic reaction, and oxygen depletion.

AB - An amperometric thin-film glucose biosensor based on a plasma-polymerized film using hexamethyldisiloxane as the monomer is presented. The plasma-polymerized film, achieved in plasma in the vapor phase, offers a new alternative for use in the design of the electrode-enzyme interface of biosensors. The film shows promise of high sensor performance; namely, rapid sensor response, low noise, a wide dynamic range, reproducibility, and reduction in the effects of interfering materials such as ascorbic acid. In this study, we examined the usefulness of the hexamethyl-disiloxane plasma-polymerized film and investigated how the thickness of the plasma-polymerized film on a platinum electrode affected sensor characteristics: the selectivity for hydrogen peroxide versus interfering agents, the sensor response due to enzymatic reaction, and oxygen depletion.

KW - Biosensor

KW - Enzyme

KW - Glucose

KW - Hexamethyldisiloxane

KW - Plasma-polymerized film

UR - http://www.scopus.com/inward/record.url?scp=1442308668&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=1442308668&partnerID=8YFLogxK

M3 - Article

VL - E87-C

SP - 142

EP - 147

JO - IEICE Transactions on Electronics

JF - IEICE Transactions on Electronics

SN - 0916-8524

IS - 2

ER -