A Thin-Film Glucose Biosensor Based on Hexamethyldisiloxane Plasma-Polymerized Film: Influence of Its Film Thickness on the Platinum Electrode

Yoshihiro Kase, Hitoshi Muguruma, Atsunori Hiratsuka, Isao Karube

Research output: Contribution to journalArticle

6 Citations (Scopus)


An amperometric thin-film glucose biosensor based on a plasma-polymerized film using hexamethyldisiloxane as the monomer is presented. The plasma-polymerized film, achieved in plasma in the vapor phase, offers a new alternative for use in the design of the electrode-enzyme interface of biosensors. The film shows promise of high sensor performance; namely, rapid sensor response, low noise, a wide dynamic range, reproducibility, and reduction in the effects of interfering materials such as ascorbic acid. In this study, we examined the usefulness of the hexamethyl-disiloxane plasma-polymerized film and investigated how the thickness of the plasma-polymerized film on a platinum electrode affected sensor characteristics: the selectivity for hydrogen peroxide versus interfering agents, the sensor response due to enzymatic reaction, and oxygen depletion.

Original languageEnglish
Pages (from-to)142-147
Number of pages6
JournalIEICE Transactions on Electronics
Issue number2
Publication statusPublished - 2004 Feb



  • Biosensor
  • Enzyme
  • Glucose
  • Hexamethyldisiloxane
  • Plasma-polymerized film

ASJC Scopus subject areas

  • Electrical and Electronic Engineering

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