A unique method for highly enantioselective synthesis of N–C axially chiral compounds

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Abstract

In this issue of Chem, Zhou and co-workers report a new strategy for synthesizing optically active N–C axially chiral compounds. In the presence of a chiral norbornene-ester-Pd catalyst, the Catellani reaction of iodobenzene derivatives with N-(2-substituted-phenyl)-2-bromobenzamides proceeds in a highly enantioselective manner to give N–C axially chiral N-aryl-phenanthridinone derivatives.

Original languageEnglish
Pages (from-to)1696-1698
Number of pages3
JournalChem
Volume7
Issue number7
DOIs
Publication statusPublished - 2021 Jul 8

ASJC Scopus subject areas

  • Chemistry(all)
  • Biochemistry
  • Environmental Chemistry
  • Chemical Engineering(all)
  • Biochemistry, medical
  • Materials Chemistry

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