TY - JOUR
T1 - Alkynyl-functionalization of hydroxypropyl cellulose and thermoresponsive hydrogel thereof prepared with P(NIPAAm-co-HEMAPCL)
AU - Miao, Lei
AU - Hu, Jiwen
AU - Lu, Mangeng
AU - Tu, Yuanyuan
AU - Chen, Xin
AU - Li, Yinwen
AU - Lin, Shudong
AU - Li, Fei
AU - Hu, Shengyu
N1 - Funding Information:
We wish to thank the National Natural Science Foundation of China (No. 51173204 , 5120319 , 21404121 , and 21404122 ), Guangdong Natural Science Foundation (No. 2014A030310426 ), the Special Funded Project of Pearl River in Guangzhou City of Nova of Science and Technology, Strategic Emerging Industry Development Special Fund in Guangdong Province, Production-education-research project in Guangdong Province (No. 2012B090400036 ), Science and Technology Program of Guangzhou City (No. 2013J4500056 ), and Science Research Special Project of Guangzhou City (No. 2014J4100216 ) for providing financial support. We also thank Dr. Ian Wyman for proof reading this paper.
PY - 2016/2/10
Y1 - 2016/2/10
N2 - A ternary system thermoresponsive hydrogel, poly(N-isopropylacrylamide-co-hydroxyethyl methylacrylate polycaprolactone)/hydroxypropyl cellulose (or P(NIPAAm-co-HEMAPCL)/HPC), was prepared via "alkynyl/azide" click chemistry between the azide modified graft copolymer P(NIPAAm-co-HEMAPCL-N3) and the alkynyl modified HPC (or alkynyl-HPC). The structures of P(NIPAAm-co-HEMAPCL-N3) and alkynyl-HPC were characterized by 1H NMR, SEC and FT-IR, and the results demonstrated that the mole ratio of the alkynyl and azide functional groups, and the feed ratios of HPC, PCL, and PNIPAAm could be easily adjusted. The incorporation of PCL and HPC dramatically enhanced the compression modulus of the P(NIPAAm-co-HEMAPCL)/HPC hydrogel, which ranged from 500 to 1000 g/cm2. Due to the immiscibility of HPC and PCL, a heterogeneous and semicontinuous structure was observed via SEM. The incorporation of HPC accelerated the water absorption rate and enhanced the hydrogel's ability to shed water. The swelling-deswelling and compressive properties could also be adjusted by changing the feeding ratio. The hydrogel exhibited reversible swelling-deswelling behavior after three "swelling-deswelling" cycles.
AB - A ternary system thermoresponsive hydrogel, poly(N-isopropylacrylamide-co-hydroxyethyl methylacrylate polycaprolactone)/hydroxypropyl cellulose (or P(NIPAAm-co-HEMAPCL)/HPC), was prepared via "alkynyl/azide" click chemistry between the azide modified graft copolymer P(NIPAAm-co-HEMAPCL-N3) and the alkynyl modified HPC (or alkynyl-HPC). The structures of P(NIPAAm-co-HEMAPCL-N3) and alkynyl-HPC were characterized by 1H NMR, SEC and FT-IR, and the results demonstrated that the mole ratio of the alkynyl and azide functional groups, and the feed ratios of HPC, PCL, and PNIPAAm could be easily adjusted. The incorporation of PCL and HPC dramatically enhanced the compression modulus of the P(NIPAAm-co-HEMAPCL)/HPC hydrogel, which ranged from 500 to 1000 g/cm2. Due to the immiscibility of HPC and PCL, a heterogeneous and semicontinuous structure was observed via SEM. The incorporation of HPC accelerated the water absorption rate and enhanced the hydrogel's ability to shed water. The swelling-deswelling and compressive properties could also be adjusted by changing the feeding ratio. The hydrogel exhibited reversible swelling-deswelling behavior after three "swelling-deswelling" cycles.
KW - Hydrogels
KW - Hydroxypropyl cellulose
KW - Poly(N-isopropylacrylamide)
KW - Polycaprolactone
KW - Thermoresponsive
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U2 - 10.1016/j.carbpol.2015.11.001
DO - 10.1016/j.carbpol.2015.11.001
M3 - Article
C2 - 26686148
AN - SCOPUS:84947746163
VL - 137
SP - 433
EP - 440
JO - Carbohydrate Polymers
JF - Carbohydrate Polymers
SN - 0144-8617
ER -