Abstract
We have demonstrated anodic alkoxylation of lactams followed by reactions with carbon nucleophiles in a one-pot manner using 1,1,1,3,3,3- hexafluoroisopropanol (HFIP) as a solvent. In the two-step transformation, HFIP acted as a nucleophile in the presence of solid-supported bases, while it acted as an inert solvent in the absence of solidsupported bases. This enabled us to conduct anodic alkoxylation of lactams and subsequent C-C bond forming reactions without replacing the solvent.
Original language | English |
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Pages (from-to) | 353-355 |
Number of pages | 3 |
Journal | Electrochemistry |
Volume | 81 |
Issue number | 5 |
DOIs | |
Publication status | Published - 2013 May |
Keywords
- Anodic alkoxylation
- Carbon-carbon bond forming reactions
- Hfip
- Solid-supported bases
ASJC Scopus subject areas
- Electrochemistry