Antioxidative polyphenolic substances in cacao liquor

Naomi Osakabe, M. Yamagishi, M. Natsume, T. Takizawa, T. Nakamura, T. Osawa

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

We have found antioxidative polyphenolic substances in cacao liquor that is one of the ingredients of chocolate and cocoa. Epicatechin, catechin, clovamide, quercetine, and their glycosides were confirmed as major antioxidants by using several methods. Furthermore, the physiological effects of crude polyphenols derived from cacao liquor (CLP) were examined with experimental animal models. CLP showed 1) antiulceric activity induced by ethanol, 2) inhibition on oxidative stress in vitamin E deficient rats, 3) reduction on LDL oxidative susceptibility in hypercholesterolemic rabbit, 4) antimutagenic effect against heterocyclic amines, 5) inhibitory effect on tumor promotion in two-stage carcinogenesis in mouse skin.

Original languageEnglish
Pages (from-to)88-101
Number of pages14
JournalACS Symposium Series
Volume754
Publication statusPublished - 2000
Externally publishedYes

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Cocoa
Glycosides
Oxidative stress
Catechin
Vitamins
Antioxidants
Rats
Tumors
Amines
Skin
Animals
Ethanol
Antimutagenic Agents
Polyphenols
Vitamin E

ASJC Scopus subject areas

  • Chemistry(all)

Cite this

Osakabe, N., Yamagishi, M., Natsume, M., Takizawa, T., Nakamura, T., & Osawa, T. (2000). Antioxidative polyphenolic substances in cacao liquor. ACS Symposium Series, 754, 88-101.

Antioxidative polyphenolic substances in cacao liquor. / Osakabe, Naomi; Yamagishi, M.; Natsume, M.; Takizawa, T.; Nakamura, T.; Osawa, T.

In: ACS Symposium Series, Vol. 754, 2000, p. 88-101.

Research output: Contribution to journalArticle

Osakabe, N, Yamagishi, M, Natsume, M, Takizawa, T, Nakamura, T & Osawa, T 2000, 'Antioxidative polyphenolic substances in cacao liquor', ACS Symposium Series, vol. 754, pp. 88-101.
Osakabe N, Yamagishi M, Natsume M, Takizawa T, Nakamura T, Osawa T. Antioxidative polyphenolic substances in cacao liquor. ACS Symposium Series. 2000;754:88-101.
Osakabe, Naomi ; Yamagishi, M. ; Natsume, M. ; Takizawa, T. ; Nakamura, T. ; Osawa, T. / Antioxidative polyphenolic substances in cacao liquor. In: ACS Symposium Series. 2000 ; Vol. 754. pp. 88-101.
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