Bio-optic gas visualization system (Sniff-cam) for human volatiles

Kohji Mitsubayashi, Kenta Iitani, Koji Toma, Takahiro Arakawa

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

A bio-optic gas-imaging system (sniff-cam) with enzyme immobilized mesh demonstrates a spatiotemporal gasimaging for human volatiles (i.e., ethanol, acetaldehyde, etc. after drinking). A bio-fluorometric technique was applied to improve the sensitivity of the gas visualization system. The bio-fluorometric sniff-cam for ethanol was constructed with alcohol dehydrogenase (ADH) immobilized mesh and the NADH imaging unit (UV-LED array and highly sensitive CMOS), thus imaging human ethanol in the gas phase not only exhaled air but also transcutaneous vapor after drinking. The sniffer system would be useful for detecting the volatile biomarkers.

Original languageEnglish
Title of host publicationBiomedical Imaging and Sensing Conference 2021
EditorsToyohiko Yatagai, Yoshihisa Aizu, Osamu Matoba, Yasuhiro Awatsuji, Yuan Luo
PublisherSPIE
ISBN (Electronic)9781510647190
DOIs
Publication statusPublished - 2021
Externally publishedYes
EventBiomedical Imaging and Sensing Conference 2021 - Virtual, Online, Japan
Duration: 2021 Apr 202021 Apr 22

Publication series

NameProceedings of SPIE - The International Society for Optical Engineering
Volume11925
ISSN (Print)0277-786X
ISSN (Electronic)1996-756X

Conference

ConferenceBiomedical Imaging and Sensing Conference 2021
Country/TerritoryJapan
CityVirtual, Online
Period21/4/2021/4/22

Keywords

  • ADH
  • Bio-optic gas visualization
  • Biofluorometry
  • Breath
  • LED
  • Transcutaneous vapor
  • VOCs

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Computer Science Applications
  • Applied Mathematics
  • Electrical and Electronic Engineering

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