Catalytic asymmetric iodocarbocyclization reaction

Tadashi Inoue, Osamu Kitagawa, Orie Ochiai, Motoo Shiro, Takeo Taguchi

Research output: Contribution to journalArticle

42 Citations (Scopus)

Abstract

The iodocarbocyclization reactions of 4-pentenylmalonate derivatives using 20 mol% of the chiral titanium complex in the presence of 12 end 2,6-dimethoxypyridine proceeded with high enantioselectivity to give good yields of cyclopentane derivatives. The origin of enantioselectivity in the present reaction is discussed on the basis of X-ray crystal structural data of the chiral titanium complex from acetylacetone, chiral dial and Ti(IV).

Original languageEnglish
Pages (from-to)9333-9336
Number of pages4
JournalTetrahedron Letters
Volume36
Issue number51
DOIs
Publication statusPublished - 1995 Dec 18
Externally publishedYes

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

Fingerprint Dive into the research topics of 'Catalytic asymmetric iodocarbocyclization reaction'. Together they form a unique fingerprint.

  • Cite this