Abstract
The iodocarbocyclization reactions of 4-pentenylmalonate derivatives using 20 mol% of the chiral titanium complex in the presence of 12 end 2,6-dimethoxypyridine proceeded with high enantioselectivity to give good yields of cyclopentane derivatives. The origin of enantioselectivity in the present reaction is discussed on the basis of X-ray crystal structural data of the chiral titanium complex from acetylacetone, chiral dial and Ti(IV).
| Original language | English |
|---|---|
| Pages (from-to) | 9333-9336 |
| Number of pages | 4 |
| Journal | Tetrahedron Letters |
| Volume | 36 |
| Issue number | 51 |
| DOIs | |
| Publication status | Published - 1995 Dec 18 |
| Externally published | Yes |
Fingerprint
ASJC Scopus subject areas
- Biochemistry
- Organic Chemistry
- Drug Discovery
Cite this
Catalytic asymmetric iodocarbocyclization reaction. / Inoue, Tadashi; Kitagawa, Osamu; Ochiai, Orie; Shiro, Motoo; Taguchi, Takeo.
In: Tetrahedron Letters, Vol. 36, No. 51, 18.12.1995, p. 9333-9336.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Catalytic asymmetric iodocarbocyclization reaction
AU - Inoue, Tadashi
AU - Kitagawa, Osamu
AU - Ochiai, Orie
AU - Shiro, Motoo
AU - Taguchi, Takeo
PY - 1995/12/18
Y1 - 1995/12/18
N2 - The iodocarbocyclization reactions of 4-pentenylmalonate derivatives using 20 mol% of the chiral titanium complex in the presence of 12 end 2,6-dimethoxypyridine proceeded with high enantioselectivity to give good yields of cyclopentane derivatives. The origin of enantioselectivity in the present reaction is discussed on the basis of X-ray crystal structural data of the chiral titanium complex from acetylacetone, chiral dial and Ti(IV).
AB - The iodocarbocyclization reactions of 4-pentenylmalonate derivatives using 20 mol% of the chiral titanium complex in the presence of 12 end 2,6-dimethoxypyridine proceeded with high enantioselectivity to give good yields of cyclopentane derivatives. The origin of enantioselectivity in the present reaction is discussed on the basis of X-ray crystal structural data of the chiral titanium complex from acetylacetone, chiral dial and Ti(IV).
UR - http://www.scopus.com/inward/record.url?scp=0028818652&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0028818652&partnerID=8YFLogxK
U2 - 10.1016/0040-4039(95)02021-G
DO - 10.1016/0040-4039(95)02021-G
M3 - Article
VL - 36
SP - 9333
EP - 9336
JO - Tetrahedron Letters
JF - Tetrahedron Letters
SN - 0040-4039
IS - 51
ER -