Abstract
The iodocarbocyclization reactions of 4-pentenylmalonate derivatives using 20 mol% of the chiral titanium complex in the presence of 12 end 2,6-dimethoxypyridine proceeded with high enantioselectivity to give good yields of cyclopentane derivatives. The origin of enantioselectivity in the present reaction is discussed on the basis of X-ray crystal structural data of the chiral titanium complex from acetylacetone, chiral dial and Ti(IV).
Original language | English |
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Pages (from-to) | 9333-9336 |
Number of pages | 4 |
Journal | Tetrahedron Letters |
Volume | 36 |
Issue number | 51 |
DOIs | |
Publication status | Published - 1995 Dec 18 |
Externally published | Yes |
ASJC Scopus subject areas
- Biochemistry
- Drug Discovery
- Organic Chemistry