Characterization of photoacoustic tomography system with dual illumination

Kazuhiko Fukutani, Yasuhiro Someda, Masakazu Taku, Yasufumi Asao, Shuichi Kobayashi, Takayuki Yagi, Makoto Yamakawa, Tsuyoshi Shiina, Tomoharu Sugie, Masakazu Toi

Research output: Chapter in Book/Report/Conference proceedingConference contribution

14 Citations (Scopus)


In this study, we characterized a newly developed imaging system, "dual illumination mode photoacoustic tomography (PAT) system". The PAT system can simultaneously or separately illuminate biological tissues from a forward and backward direction toward an array transducer. The shape of the custom-made transducer is rectangular, which allows direct illumination of tissue surfaces in front of the array transducer through a holding plate from the backward direction. The transducer frequency was designed at 1 MHz by considering the trade-off relationship between ultrasound attenuation and image resolution. A Ti:Sa laser optically pumped with a Q-switched Nd:YAG laser, having a tunable wavelength of 700 to 900 nm, was chosen for deep light penetration in tissues. The laser light was sufficiently expanded and homogenized to keep the level of laser-pulse fluence on the sample surface under the ANSI safety limit. System performance was tested with phantoms. The results of our study showed that the system visualized all the absorbers embedded in a 50-mm-thick tissue-mimicking phantom with a lateral resolution of 2∼3 mm.

Original languageEnglish
Title of host publicationPhotons Plus Ultrasound
Subtitle of host publicationImaging and Sensing 2011
Publication statusPublished - 2011
Externally publishedYes
EventPhotons Plus Ultrasound: Imaging and Sensing 2011 - San Francisco, CA, United States
Duration: 2011 Jan 232011 Jan 25

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
ISSN (Print)1605-7422


ConferencePhotons Plus Ultrasound: Imaging and Sensing 2011
Country/TerritoryUnited States
CitySan Francisco, CA


  • Deep tissue imaging
  • Dual illumination
  • Photoacoustic tomography

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Atomic and Molecular Physics, and Optics
  • Radiology Nuclear Medicine and imaging


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