Chiral initiator-induces self-disproportionation of enantiomers via achiral chromatography

Application to enantiomer separation of racemate

Kaori Tateishi, Shiori Tsukagoshi, Tsuyoshi Nakamura, Shotaro Watanabe, Vadim A. Soloshonok, Osamu Kitagawa

Research output: Contribution to journalArticle

17 Citations (Scopus)

Abstract

We report here the theoretical design and proof of principle of the first example of a conceptually new approach for the preparation of enantiomerically pure compounds from the racemates by chiral initiator-induced Self-Disproportionation of Enantiomers (SDE) via achiral chromatography.

Original languageEnglish
Pages (from-to)5220-5223
Number of pages4
JournalTetrahedron Letters
Volume54
Issue number38
DOIs
Publication statusPublished - 2013 Sep 18

Fingerprint

Enantiomers
Chromatography

Keywords

  • Association
  • Chromatography
  • Disproportionation
  • Enantiomers
  • Optical resolution

ASJC Scopus subject areas

  • Biochemistry
  • Organic Chemistry
  • Drug Discovery

Cite this

Chiral initiator-induces self-disproportionation of enantiomers via achiral chromatography : Application to enantiomer separation of racemate. / Tateishi, Kaori; Tsukagoshi, Shiori; Nakamura, Tsuyoshi; Watanabe, Shotaro; Soloshonok, Vadim A.; Kitagawa, Osamu.

In: Tetrahedron Letters, Vol. 54, No. 38, 18.09.2013, p. 5220-5223.

Research output: Contribution to journalArticle

Tateishi, Kaori ; Tsukagoshi, Shiori ; Nakamura, Tsuyoshi ; Watanabe, Shotaro ; Soloshonok, Vadim A. ; Kitagawa, Osamu. / Chiral initiator-induces self-disproportionation of enantiomers via achiral chromatography : Application to enantiomer separation of racemate. In: Tetrahedron Letters. 2013 ; Vol. 54, No. 38. pp. 5220-5223.
@article{e37e8e38835d47d08a31d1b0530587aa,
title = "Chiral initiator-induces self-disproportionation of enantiomers via achiral chromatography: Application to enantiomer separation of racemate",
abstract = "We report here the theoretical design and proof of principle of the first example of a conceptually new approach for the preparation of enantiomerically pure compounds from the racemates by chiral initiator-induced Self-Disproportionation of Enantiomers (SDE) via achiral chromatography.",
keywords = "Association, Chromatography, Disproportionation, Enantiomers, Optical resolution",
author = "Kaori Tateishi and Shiori Tsukagoshi and Tsuyoshi Nakamura and Shotaro Watanabe and Soloshonok, {Vadim A.} and Osamu Kitagawa",
year = "2013",
month = "9",
day = "18",
doi = "10.1016/j.tetlet.2013.07.061",
language = "English",
volume = "54",
pages = "5220--5223",
journal = "Tetrahedron Letters",
issn = "0040-4039",
publisher = "Elsevier Limited",
number = "38",

}

TY - JOUR

T1 - Chiral initiator-induces self-disproportionation of enantiomers via achiral chromatography

T2 - Application to enantiomer separation of racemate

AU - Tateishi, Kaori

AU - Tsukagoshi, Shiori

AU - Nakamura, Tsuyoshi

AU - Watanabe, Shotaro

AU - Soloshonok, Vadim A.

AU - Kitagawa, Osamu

PY - 2013/9/18

Y1 - 2013/9/18

N2 - We report here the theoretical design and proof of principle of the first example of a conceptually new approach for the preparation of enantiomerically pure compounds from the racemates by chiral initiator-induced Self-Disproportionation of Enantiomers (SDE) via achiral chromatography.

AB - We report here the theoretical design and proof of principle of the first example of a conceptually new approach for the preparation of enantiomerically pure compounds from the racemates by chiral initiator-induced Self-Disproportionation of Enantiomers (SDE) via achiral chromatography.

KW - Association

KW - Chromatography

KW - Disproportionation

KW - Enantiomers

KW - Optical resolution

UR - http://www.scopus.com/inward/record.url?scp=84881616858&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84881616858&partnerID=8YFLogxK

U2 - 10.1016/j.tetlet.2013.07.061

DO - 10.1016/j.tetlet.2013.07.061

M3 - Article

VL - 54

SP - 5220

EP - 5223

JO - Tetrahedron Letters

JF - Tetrahedron Letters

SN - 0040-4039

IS - 38

ER -