Cloning and expression of Xenopus laevis xSox12 cDNA

Naoki Komatsu, Yoshiki Hiraoka, Masahide Shiozawa, Motoyuki Ogawa, Sadakazu Aiso

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

A family of SRY-related genes has been termed SOX. We have isolated and sequenced a cDNA encoding xSox12 from Xenopus laevis ovary. The cDNA contained an open reading frame (ORF) coding for 470 amino acids encompassing an HMG box characteristic of the SOX family, a leucine zipper motif and glutamine-rich segments. The size of the xSox12 mRNA was determined to be 3.0 knt by Northern analysis. The ovary was the most prominent in the expression of the Sox mRNA among the various tissues of adult frog as far as examined.

Original languageEnglish
Pages (from-to)117-119
Number of pages3
JournalBiochimica et Biophysica Acta - Gene Structure and Expression
Volume1305
Issue number3
DOIs
Publication statusPublished - 1996 Mar 1

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Keywords

  • Molecular cloning
  • Nucleotide sequence
  • SOX
  • Xenopus laevis
  • cDNA

ASJC Scopus subject areas

  • Structural Biology
  • Biophysics
  • Biochemistry
  • Genetics

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