Cyclodextrin-peptide hybrid as a hydrolytic catalyst having multiple functional groups

Hiroshi Tsutsumi, Keita Hamasaki, Hisakazu Mihara, Akihiko Ueno

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

A designed cyclodextrin-peptide hybrid, which has multiple functional groups on its α-helix peptide backbone, has been synthesized as a catalyst for ester hydrolysis. Kinetic study revealed that the carboxylate group plays a key role in this system.

Original languageEnglish
Pages (from-to)741-743
Number of pages3
JournalBioorganic and Medicinal Chemistry Letters
Volume10
Issue number8
DOIs
Publication statusPublished - 2000 Apr

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ASJC Scopus subject areas

  • Biochemistry
  • Molecular Medicine
  • Molecular Biology
  • Pharmaceutical Science
  • Drug Discovery
  • Clinical Biochemistry
  • Organic Chemistry

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