Cyclodextrin-peptide hybrid as a hydrolytic catalyst having multiple functional groups

Hiroshi Tsutsumi, Keita Hamasaki, Hisakazu Mihara, Akihiko Ueno

Research output: Contribution to journal › Article

19 Citations (Scopus)

Abstract

A designed cyclodextrin-peptide hybrid, which has multiple functional groups on its α-helix peptide backbone, has been synthesized as a catalyst for ester hydrolysis. Kinetic study revealed that the carboxylate group plays a key role in this system. (C) 2000 Elsevier Science Ltd. All rights reserved.

Original languageEnglish
Pages (from-to)741-743
Number of pages3
JournalBioorganic and Medicinal Chemistry Letters
Volume10
Issue number8
DOIs
Publication statusPublished - 2000 Apr
Externally publishedYes

Fingerprint

Cyclodextrins
Functional groups
Peptides
Catalysts
Hydrolysis
Esters
Kinetics

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Biology
  • Organic Chemistry
  • Drug Discovery
  • Pharmaceutical Science

Cite this

Cyclodextrin-peptide hybrid as a hydrolytic catalyst having multiple functional groups. / Tsutsumi, Hiroshi; Hamasaki, Keita; Mihara, Hisakazu; Ueno, Akihiko.

In: Bioorganic and Medicinal Chemistry Letters, Vol. 10, No. 8, 04.2000, p. 741-743.

Research output: Contribution to journal › Article

Tsutsumi, H, Hamasaki, K, Mihara, H & Ueno, A 2000, 'Cyclodextrin-peptide hybrid as a hydrolytic catalyst having multiple functional groups', Bioorganic and Medicinal Chemistry Letters, vol. 10, no. 8, pp. 741-743. https://doi.org/10.1016/S0960-894X(00)00090-1
Tsutsumi H, Hamasaki K, Mihara H, Ueno A. Cyclodextrin-peptide hybrid as a hydrolytic catalyst having multiple functional groups. Bioorganic and Medicinal Chemistry Letters. 2000 Apr;10(8):741-743. https://doi.org/10.1016/S0960-894X(00)00090-1
Tsutsumi, Hiroshi ; Hamasaki, Keita ; Mihara, Hisakazu ; Ueno, Akihiko. / Cyclodextrin-peptide hybrid as a hydrolytic catalyst having multiple functional groups. In: Bioorganic and Medicinal Chemistry Letters. 2000 ; Vol. 10, No. 8. pp. 741-743.
@article{5cf95d425e1f4735aedbcc076fce835d,
title = "Cyclodextrin-peptide hybrid as a hydrolytic catalyst having multiple functional groups",
abstract = "A designed cyclodextrin-peptide hybrid, which has multiple functional groups on its α-helix peptide backbone, has been synthesized as a catalyst for ester hydrolysis. Kinetic study revealed that the carboxylate group plays a key role in this system. (C) 2000 Elsevier Science Ltd. All rights reserved.",
author = "Hiroshi Tsutsumi and Keita Hamasaki and Hisakazu Mihara and Akihiko Ueno",
year = "2000",
month = "4",
doi = "10.1016/S0960-894X(00)00090-1",
language = "English",
volume = "10",
pages = "741--743",
journal = "Bioorganic and Medicinal Chemistry Letters",
issn = "0960-894X",
publisher = "Elsevier Limited",
number = "8",

}

TY - JOUR

T1 - Cyclodextrin-peptide hybrid as a hydrolytic catalyst having multiple functional groups

AU - Tsutsumi, Hiroshi

AU - Hamasaki, Keita

AU - Mihara, Hisakazu

AU - Ueno, Akihiko

PY - 2000/4

Y1 - 2000/4

N2 - A designed cyclodextrin-peptide hybrid, which has multiple functional groups on its α-helix peptide backbone, has been synthesized as a catalyst for ester hydrolysis. Kinetic study revealed that the carboxylate group plays a key role in this system. (C) 2000 Elsevier Science Ltd. All rights reserved.

AB - A designed cyclodextrin-peptide hybrid, which has multiple functional groups on its α-helix peptide backbone, has been synthesized as a catalyst for ester hydrolysis. Kinetic study revealed that the carboxylate group plays a key role in this system. (C) 2000 Elsevier Science Ltd. All rights reserved.

UR - http://www.scopus.com/inward/record.url?scp=0034678837&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0034678837&partnerID=8YFLogxK

U2 - 10.1016/S0960-894X(00)00090-1

DO - 10.1016/S0960-894X(00)00090-1

M3 - Article

C2 - 10782676

AN - SCOPUS:0034678837

VL - 10

SP - 741

EP - 743

JO - Bioorganic and Medicinal Chemistry Letters

JF - Bioorganic and Medicinal Chemistry Letters

SN - 0960-894X

IS - 8

ER -

Access to Document