Abstract
A designed cyclodextrin-peptide hybrid, which has multiple functional groups on its α-helix peptide backbone, has been synthesized as a catalyst for ester hydrolysis. Kinetic study revealed that the carboxylate group plays a key role in this system.
| Original language | English |
|---|---|
| Pages (from-to) | 741-743 |
| Number of pages | 3 |
| Journal | Bioorganic and Medicinal Chemistry Letters |
| Volume | 10 |
| Issue number | 8 |
| DOIs | |
| Publication status | Published - 2000 Apr |
ASJC Scopus subject areas
- Biochemistry
- Molecular Medicine
- Molecular Biology
- Pharmaceutical Science
- Drug Discovery
- Clinical Biochemistry
- Organic Chemistry
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Cite this
Tsutsumi, H., Hamasaki, K., Mihara, H., & Ueno, A. (2000). Cyclodextrin-peptide hybrid as a hydrolytic catalyst having multiple functional groups. Bioorganic and Medicinal Chemistry Letters, 10(8), 741-743. https://doi.org/10.1016/S0960-894X(00)00090-1