Design and fabrication of air-flow based single particle dispensing system

Tomohiro Kawahara, Shigeo Ohashi, Masaya Hagiwara, Yoko Yamanishi, Fumihito Arai

Research output: Chapter in Book/Report/Conference proceedingConference contribution

4 Citations (Scopus)

Abstract

In this paper, we discuss the design and fabrication approach to increase the success rate of single particle dispensing. Two pairs of capacitance sensors are placed in a biochip to detect the flow velocity of particles, and the air pressure is applied to eject particles by synchronizing the timing. Comprehensive design theory, which is taken into account of the back pressure caused by air pressure, the response time of the system, sensor property, and the delay of the dispensing from the air pressure, is developed in order to minimize the disturbance of the system and maximize the throughput of the ejection system. Then, the system has capability to eject 3 particles/sec and maximum flow velocity is 10 mm/s. The novelty of the system is that the biochip is disposable which is unlike the conventional mechanical inkjet system and it can prevent contamination. Therefore, the fabricated disposable biochip based on photolithography is low cost and the drive system is reusable. Finally, we succeed in automatic dispensing of a single particle (=100 μm) from a biochip to culture well atmosphere using developed cell ejection system with the success rate of 50 %.

Original languageEnglish
Title of host publicationIEEE International Conference on Intelligent Robots and Systems
Pages1309-1314
Number of pages6
DOIs
Publication statusPublished - 2011
Externally publishedYes
Event2011 IEEE/RSJ International Conference on Intelligent Robots and Systems: Celebrating 50 Years of Robotics, IROS'11 - San Francisco, CA
Duration: 2011 Sep 252011 Sep 30

Other

Other2011 IEEE/RSJ International Conference on Intelligent Robots and Systems: Celebrating 50 Years of Robotics, IROS'11
CitySan Francisco, CA
Period11/9/2511/9/30

Fingerprint

Biochips
Fabrication
Air
Flow velocity
Sensors
Photolithography
Contamination
Capacitance
Throughput
Costs

ASJC Scopus subject areas

  • Control and Systems Engineering
  • Software
  • Computer Vision and Pattern Recognition
  • Computer Science Applications

Cite this

Kawahara, T., Ohashi, S., Hagiwara, M., Yamanishi, Y., & Arai, F. (2011). Design and fabrication of air-flow based single particle dispensing system. In IEEE International Conference on Intelligent Robots and Systems (pp. 1309-1314). [6048514] https://doi.org/10.1109/IROS.2011.6048514

Design and fabrication of air-flow based single particle dispensing system. / Kawahara, Tomohiro; Ohashi, Shigeo; Hagiwara, Masaya; Yamanishi, Yoko; Arai, Fumihito.

IEEE International Conference on Intelligent Robots and Systems. 2011. p. 1309-1314 6048514.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Kawahara, T, Ohashi, S, Hagiwara, M, Yamanishi, Y & Arai, F 2011, Design and fabrication of air-flow based single particle dispensing system. in IEEE International Conference on Intelligent Robots and Systems., 6048514, pp. 1309-1314, 2011 IEEE/RSJ International Conference on Intelligent Robots and Systems: Celebrating 50 Years of Robotics, IROS'11, San Francisco, CA, 11/9/25. https://doi.org/10.1109/IROS.2011.6048514
Kawahara T, Ohashi S, Hagiwara M, Yamanishi Y, Arai F. Design and fabrication of air-flow based single particle dispensing system. In IEEE International Conference on Intelligent Robots and Systems. 2011. p. 1309-1314. 6048514 https://doi.org/10.1109/IROS.2011.6048514
Kawahara, Tomohiro ; Ohashi, Shigeo ; Hagiwara, Masaya ; Yamanishi, Yoko ; Arai, Fumihito. / Design and fabrication of air-flow based single particle dispensing system. IEEE International Conference on Intelligent Robots and Systems. 2011. pp. 1309-1314
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