Design of a nucleobase-conjugated peptide that recognizes HIV-1 RRE IIB RNA with high affinity and specificity

Tsuyoshi Takahashi; Keita Hamasaki; Ichiro Kumagai; Akihiko Ueno; Hisakazu Mihara

doi:10.1039/a909579i

Design of a nucleobase-conjugated peptide that recognizes HIV-1 RRE IIB RNA with high affinity and specificity

Tsuyoshi Takahashi, Keita Hamasaki, Ichiro Kumagai, Akihiko Ueno, Hisakazu Mihara

Research output: Contribution to journal › Article › peer-review

14 Citations (Scopus)

Abstract

A nucleobase-conjugated peptide, derived from HIV-1 Rev, was designed and synthesized, and the peptide which contained the cytosine moiety at the L-α-amino acid side chain bound RRE IIB RNA with high affinity and high specificity.

Original language	English
Pages (from-to)	349-350
Number of pages	2
Journal	Chemical Communications
Issue number	5
DOIs	https://doi.org/10.1039/a909579i
Publication status	Published - 2000 Mar 7
Externally published	Yes

ASJC Scopus subject areas

Catalysis
Electronic, Optical and Magnetic Materials
Ceramics and Composites
Chemistry(all)
Surfaces, Coatings and Films
Metals and Alloys
Materials Chemistry

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10.1039/a909579i

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title = "Design of a nucleobase-conjugated peptide that recognizes HIV-1 RRE IIB RNA with high affinity and specificity",

abstract = "A nucleobase-conjugated peptide, derived from HIV-1 Rev, was designed and synthesized, and the peptide which contained the cytosine moiety at the L-α-amino acid side chain bound RRE IIB RNA with high affinity and high specificity.",

author = "Tsuyoshi Takahashi and Keita Hamasaki and Ichiro Kumagai and Akihiko Ueno and Hisakazu Mihara",

year = "2000",

month = mar,

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doi = "10.1039/a909579i",

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AU - Takahashi, Tsuyoshi

AU - Hamasaki, Keita

AU - Kumagai, Ichiro

AU - Ueno, Akihiko

AU - Mihara, Hisakazu

PY - 2000/3/7

Y1 - 2000/3/7

N2 - A nucleobase-conjugated peptide, derived from HIV-1 Rev, was designed and synthesized, and the peptide which contained the cytosine moiety at the L-α-amino acid side chain bound RRE IIB RNA with high affinity and high specificity.

AB - A nucleobase-conjugated peptide, derived from HIV-1 Rev, was designed and synthesized, and the peptide which contained the cytosine moiety at the L-α-amino acid side chain bound RRE IIB RNA with high affinity and high specificity.

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JO - Chemical Communications

JF - Chemical Communications

SN - 1359-7345

IS - 5

ER -

Design of a nucleobase-conjugated peptide that recognizes HIV-1 RRE IIB RNA with high affinity and specificity

Abstract

ASJC Scopus subject areas

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