Design of a nucleobase-conjugated peptide that recognizes HIV-1 RRE IIB RNA with high affinity and specificity

Tsuyoshi Takahashi, Keita Hamasaki, Ichiro Kumagai, Akihiko Ueno, Hisakazu Mihara

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10 Citations (Scopus)

Abstract

A nucleobase-conjugated peptide, derived from HIV-1 Rev, was designed and synthesized, and the peptide which contained the cytosine moiety at the L-α-amino acid side chain bound RRE IIB RNA with high affinity and high specificity.

Original languageEnglish
Pages (from-to)349-350
Number of pages2
JournalChemical Communications
Issue number5
Publication statusPublished - 2000 Mar 7
Externally publishedYes

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ASJC Scopus subject areas

  • Chemistry(all)

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