Design of a nucleobase-conjugated peptide that recognizes HIV-1 RRE IIB RNA with high affinity and specificity

Tsuyoshi Takahashi, Keita Hamasaki, Ichiro Kumagai, Akihiko Ueno, Hisakazu Mihara

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

A nucleobase-conjugated peptide, derived from HIV-1 Rev, was designed and synthesized, and the peptide which contained the cytosine moiety at the L-α-amino acid side chain bound RRE IIB RNA with high affinity and high specificity.

Original languageEnglish
Pages (from-to)349-350
Number of pages2
JournalChemical Communications
Issue number5
Publication statusPublished - 2000 Mar 7
Externally publishedYes

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RNA
Peptides
Cytosine
Amino acids
Amino Acids

ASJC Scopus subject areas

  • Chemistry(all)

Cite this

Design of a nucleobase-conjugated peptide that recognizes HIV-1 RRE IIB RNA with high affinity and specificity. / Takahashi, Tsuyoshi; Hamasaki, Keita; Kumagai, Ichiro; Ueno, Akihiko; Mihara, Hisakazu.

In: Chemical Communications, No. 5, 07.03.2000, p. 349-350.

Research output: Contribution to journalArticle

Takahashi, Tsuyoshi ; Hamasaki, Keita ; Kumagai, Ichiro ; Ueno, Akihiko ; Mihara, Hisakazu. / Design of a nucleobase-conjugated peptide that recognizes HIV-1 RRE IIB RNA with high affinity and specificity. In: Chemical Communications. 2000 ; No. 5. pp. 349-350.
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