Design of artificial pepetides that recognize the HIV RRE IIB RNA.

T. Takahashi, I. Kumagai, K. Hamasaki, A. Ueno, H. Mihara

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Abstract

Peptide nucleic acid (PNA) conjugated peptides, derived from HIV-1 Rev, were designed and synthesized in order to construct molecules that recognize HIV RRE IIB RNA. The competitive binding analyses using fluorescent Rev peptide revealed that the PNA unit on the peptide affected the RNA binding.

Original languageEnglish
Pages (from-to)271-272
Number of pages2
JournalNucleic acids symposium series
Issue number42
Publication statusPublished - 1999

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ASJC Scopus subject areas

  • Medicine(all)

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Takahashi, T., Kumagai, I., Hamasaki, K., Ueno, A., & Mihara, H. (1999). Design of artificial pepetides that recognize the HIV RRE IIB RNA. Nucleic acids symposium series, (42), 271-272.