Abstract
A response current may be changed by fouling caused by protein or fibrobrast adsorption when a glucose sensor is implanted, fly making the slope of glucose concentration in an enzyme layer flat, the influence of the fouling layer can be disregarded. In the present studs ferrocene binding with bovine serum albumin was used as a mediator of the glucose sensor. The proportionality between transient current of after activation of glucose oxidase controlled by pulse potential and glucose concentration was examined. As a result reaction right after the activation was not controlled by glucose diffusion, and transient current was dependent on glucose concentration. In conclusion glucose concentration is determinable by measurement of transient current after the activation of glucose oxidase in the enzyme layer, and this method is applicable to long-term monitoring of glucose concentration.
| Original language | English |
|---|---|
| Pages (from-to) | 749-751 |
| Number of pages | 3 |
| Journal | Japanese Journal of Artificial Organs |
| Volume | 26 |
| Issue number | 3 |
| Publication status | Published - 1997 |
| Externally published | Yes |
Keywords
- glucose
- glucose concentration
- glucose oxidase
- glucose sensor
- transient current
ASJC Scopus subject areas
- Biophysics
Cite this
Development of an enzyme activity on-off switchable type glucose sensor using polymeric mediator. / Taniyama, Y.; Miyasaka, T.; Yoshimi, Yasuo; Sakai, K.
In: Japanese Journal of Artificial Organs, Vol. 26, No. 3, 1997, p. 749-751.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Development of an enzyme activity on-off switchable type glucose sensor using polymeric mediator
AU - Taniyama, Y.
AU - Miyasaka, T.
AU - Yoshimi, Yasuo
AU - Sakai, K.
PY - 1997
Y1 - 1997
N2 - A response current may be changed by fouling caused by protein or fibrobrast adsorption when a glucose sensor is implanted, fly making the slope of glucose concentration in an enzyme layer flat, the influence of the fouling layer can be disregarded. In the present studs ferrocene binding with bovine serum albumin was used as a mediator of the glucose sensor. The proportionality between transient current of after activation of glucose oxidase controlled by pulse potential and glucose concentration was examined. As a result reaction right after the activation was not controlled by glucose diffusion, and transient current was dependent on glucose concentration. In conclusion glucose concentration is determinable by measurement of transient current after the activation of glucose oxidase in the enzyme layer, and this method is applicable to long-term monitoring of glucose concentration.
AB - A response current may be changed by fouling caused by protein or fibrobrast adsorption when a glucose sensor is implanted, fly making the slope of glucose concentration in an enzyme layer flat, the influence of the fouling layer can be disregarded. In the present studs ferrocene binding with bovine serum albumin was used as a mediator of the glucose sensor. The proportionality between transient current of after activation of glucose oxidase controlled by pulse potential and glucose concentration was examined. As a result reaction right after the activation was not controlled by glucose diffusion, and transient current was dependent on glucose concentration. In conclusion glucose concentration is determinable by measurement of transient current after the activation of glucose oxidase in the enzyme layer, and this method is applicable to long-term monitoring of glucose concentration.
KW - glucose
KW - glucose concentration
KW - glucose oxidase
KW - glucose sensor
KW - transient current
UR - http://www.scopus.com/inward/record.url?scp=0030981606&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0030981606&partnerID=8YFLogxK
M3 - Article
VL - 26
SP - 749
EP - 751
JO - Japanese Journal of Artificial Organs
JF - Japanese Journal of Artificial Organs
SN - 0300-0818
IS - 3
ER -