Development of electrolytic cell with cell-culture for metallic biomaterials

S. Hiromoto, K. Noda, T. Hanawa

Research output: Contribution to journalArticle

44 Citations (Scopus)

Abstract

The interface reactions between materials and tissues must be understood to improve the corrosion resistance in vivo and biocompatibility of the materials. Then, we have developed a new electrolytic cell by which electrochemical measurement can be performed during culturing cells on specimen. Open-circuit potential (Eopen) and AC impedance of commercially pure titanium at Eopen were measured in a cell-culture medium with and without culturing murine fibroblasts L929 and in the medium without proteins. The biomolecule adsorption layer containing proteins and cells was formed on titanium oxide film and worked as a capacitor by preventing the diffusion of molecules. The cell enhanced this prevention.

Original languageEnglish
Pages (from-to)955-965
Number of pages11
JournalCorrosion Science
Volume44
Issue number5
DOIs
Publication statusPublished - 2002 May
Externally publishedYes

Fingerprint

Electrolytic cells
Biocompatible Materials
Cell culture
Biomaterials
Proteins
Titanium oxides
Biomolecules
Fibroblasts
Titanium
Biocompatibility
Oxide films
Culture Media
Corrosion resistance
Capacitors
Tissue
Adsorption
Molecules
Networks (circuits)
titanium dioxide

Keywords

  • Biocompatibility
  • Cell-culture
  • EIS
  • Interfaces
  • Metallic biomaterials
  • Titanium

ASJC Scopus subject areas

  • Materials Science(all)
  • Metals and Alloys

Cite this

Development of electrolytic cell with cell-culture for metallic biomaterials. / Hiromoto, S.; Noda, K.; Hanawa, T.

In: Corrosion Science, Vol. 44, No. 5, 05.2002, p. 955-965.

Research output: Contribution to journalArticle

Hiromoto, S. ; Noda, K. ; Hanawa, T. / Development of electrolytic cell with cell-culture for metallic biomaterials. In: Corrosion Science. 2002 ; Vol. 44, No. 5. pp. 955-965.
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