TY - JOUR
T1 - Development of tablet-shaped ingestible core-body thermometer powered by gastric acid battery
AU - Yoshida, Shinya
AU - Miyaguchi, Hiroshi
AU - Nakamura, Tsutomu
N1 - Funding Information:
Manuscript received July 4, 2018; accepted September 14, 2018. Date of publication September 20, 2018; date of current version November 13, 2018. This work was supported in part by the Center of Innovation Program, Japan, in part by the Nakatani Foundation, and in part by the Kato Foundation for Promotion of Science. The associate editor coordinating the review of this paper and approving it for publication was Dr. Pantelis Georgiou. (Corresponding author: Shinya Yoshida.) S. Yoshida is with the Department of Robotics, Tohoku University, Sendai 980-8579, Japan (e-mail: s-yoshida@mems.mech.tohoku.ac.jp).
Publisher Copyright:
© 2018 IEEE.
PY - 2018/12/1
Y1 - 2018/12/1
N2 - In this paper, we have developed a tablet-shaped ingestible core-body temperature sensor based on gastric acid power generation for daily health care. A custom integrated circuit (IC), which had voltage boosting, bit-rate conversion, coding, modulating, and transmitting functions, was prototyped for the feasibility study of this system. A pair of Mg and Au electrodes was chosen as the negative and positive electrodes for the gastric acid battery, respectively. The battery with a diameter of 2 mm in an artificial gastric juice generated approximately 1.2 V of output voltage. Subsequently, it successfully boosted the generated voltages to more than 3.5 V by the custom IC and demonstrated the charging of a multilayer ceramic capacitor at the boosted voltage within a reasonably short time. The feasibility of mass production of the Mg thin-film-based battery on a print circuit board (PCB) was also verified through sputter deposition of a Mg thin film on a Au pad of a PCB. Next, electrical components of diameter approximately 7 mm were mounted on the PCBs and compactly packaged with a resin. Consequently, a tablet-shaped device of diameter 10 mm and height 8 mm was prototyped as a specimen for a telemetry experiment. Finally, we successfully demonstrated that the temperature data measured by the device in pork were transferred to a commercially available loop antenna as a receiver at a distance of more than 20 cm via magnetic-field coupling telecommunication. This achievement paves the way to realizing a safe and ingestible core-body thermometer for daily use.
AB - In this paper, we have developed a tablet-shaped ingestible core-body temperature sensor based on gastric acid power generation for daily health care. A custom integrated circuit (IC), which had voltage boosting, bit-rate conversion, coding, modulating, and transmitting functions, was prototyped for the feasibility study of this system. A pair of Mg and Au electrodes was chosen as the negative and positive electrodes for the gastric acid battery, respectively. The battery with a diameter of 2 mm in an artificial gastric juice generated approximately 1.2 V of output voltage. Subsequently, it successfully boosted the generated voltages to more than 3.5 V by the custom IC and demonstrated the charging of a multilayer ceramic capacitor at the boosted voltage within a reasonably short time. The feasibility of mass production of the Mg thin-film-based battery on a print circuit board (PCB) was also verified through sputter deposition of a Mg thin film on a Au pad of a PCB. Next, electrical components of diameter approximately 7 mm were mounted on the PCBs and compactly packaged with a resin. Consequently, a tablet-shaped device of diameter 10 mm and height 8 mm was prototyped as a specimen for a telemetry experiment. Finally, we successfully demonstrated that the temperature data measured by the device in pork were transferred to a commercially available loop antenna as a receiver at a distance of more than 20 cm via magnetic-field coupling telecommunication. This achievement paves the way to realizing a safe and ingestible core-body thermometer for daily use.
KW - core-body thermometer
KW - gastric power generation
KW - Ingestible
KW - pill
KW - stomach
KW - swallowable
KW - tablet
KW - telemetry
KW - wireless
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U2 - 10.1109/JSEN.2018.2871064
DO - 10.1109/JSEN.2018.2871064
M3 - Article
AN - SCOPUS:85053613083
VL - 18
SP - 9755
EP - 9762
JO - IEEE Sensors Journal
JF - IEEE Sensors Journal
SN - 1530-437X
IS - 23
M1 - 8469104
ER -