Diastereoselective α-iodination reaction of 4-alkenylamide having a β-chiral center

Midori Okada, Osamu Kitagawa, Tokushi Hanano, Takeo Taguchi

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4 Citations (Scopus)

Abstract

α-Iodination reaction of 4-alkenylamide with a β-chiral center proceeds with high diastereoseletivity to give syn α-iodoalkenamide through the formation of cyclic ketene N,O-acetal and subsequent α-iodination from the opposite side of a β-substituent.

Original languageEnglish
Pages (from-to)6825-6834
Number of pages10
JournalTetrahedron
Volume53
Issue number20
DOIs
Publication statusPublished - 1997 May 19
Externally publishedYes

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ASJC Scopus subject areas

  • Biochemistry
  • Organic Chemistry
  • Drug Discovery

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