Diels-Alder reaction of N-allylic enamides and lactam derivatives through iodine mediated activation

Osamu Kitagawa, Katsuyuki Aoki, Tadashi Inoue, Takeo Taguchi

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23 Citations (Scopus)

Abstract

The Diels-Alder reaction of N-allylic enamide and α,β-unsaturated lactam derivatives proceeded in the presence of I2 at low temperature through a cationic iodolactonization intermediate. With some substrates, this method of activation was proved to be more effective than by use of Lewis acids.

Original languageEnglish
Pages (from-to)593-596
Number of pages4
JournalTetrahedron Letters
Volume36
Issue number4
DOIs
Publication statusPublished - 1995 Jan 23

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ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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