Dispensing of mono-dispersed micro-bubbles for cell ablation

Hiroki Kuriki, Yoko Yamanishi, Shinya Sakuma, Satoshi Akagi, Fumihito Arai

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

We have successfully produced mono-dispersed micro-gas bubbles for less than around 10 μm diameter by micro-bubble knife which produce micro-bubble in an electrically induced ultrasonic field. The discharged output power and conductive area of micro-electrode in micro-bubble knife which cuts the cell by micro-bubble were controlled by glass shell insulation around the copper micro-wire. A small space which is called 'bubble reservoir' between the wire and glass tip contributes to stabilize the electric discharge and directional bubble generation. The directionally dispensed bubbles can be used for processing of soft materials such as biological cells. For the present study the cell membrane has successfully processed with a few μm order resolution.

Original languageEnglish
Title of host publication2013 IEEE International Conference on Robotics and Automation, ICRA 2013
Pages2783-2788
Number of pages6
DOIs
Publication statusPublished - 2013 Nov 14
Event2013 IEEE International Conference on Robotics and Automation, ICRA 2013 - Karlsruhe, Germany
Duration: 2013 May 62013 May 10

Publication series

NameProceedings - IEEE International Conference on Robotics and Automation
ISSN (Print)1050-4729

Other

Other2013 IEEE International Conference on Robotics and Automation, ICRA 2013
CountryGermany
CityKarlsruhe
Period13/5/613/5/10

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ASJC Scopus subject areas

  • Software
  • Control and Systems Engineering
  • Artificial Intelligence
  • Electrical and Electronic Engineering

Cite this

Kuriki, H., Yamanishi, Y., Sakuma, S., Akagi, S., & Arai, F. (2013). Dispensing of mono-dispersed micro-bubbles for cell ablation. In 2013 IEEE International Conference on Robotics and Automation, ICRA 2013 (pp. 2783-2788). [6630961] (Proceedings - IEEE International Conference on Robotics and Automation). https://doi.org/10.1109/ICRA.2013.6630961