Double naphthalene-tagged cyclodextrin-peptide capable of exhibiting guest-induced naphthalene excimer fluorescence

Dewi Yana, Tomoko Shimizu, Keita Hamasaki, Hisakazu Mihara, Akihiko Ueno

Research output: Contribution to journalArticle

17 Citations (Scopus)

Abstract

A cyclodextrin-peptide hybrid (17NNβ) bearing two napthalene units in the peptide side chain has been designed and synthesized as a novel chemosensor molecule. Circular dichroism study of the compound revealed that the peptide has helix structure with a helix content of 41%. The peptide revealed both monomer and exciter emission and the intensity of the exciter amusesen increased while that of the monomer emission decreased upon addition of the guest compound. This behavior was observed for various guest molecules, sigh-getting that the system can be used for detecting molecellose in aqueous solution.

Original languageEnglish
Pages (from-to)11-15
Number of pages5
JournalMacromolecular Rapid Communications
Volume23
Issue number1
DOIs
Publication statusPublished - 2002 Jan 9

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Keywords

  • Cyclodextrins
  • Excimer fluorescence
  • Host-guest systems
  • Peptide

ASJC Scopus subject areas

  • Organic Chemistry
  • Polymers and Plastics
  • Materials Chemistry

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