Effect of spinal cord injury and its lesion level on stretch reflex modulation by cold stimulation in humans

H. Ogata, D. G. Sayenko, E. Yamamoto, T. Kitamura, Shinichirou Yamamoto, T. Miyoshi, K. Kamibayashi, K. Nakazawa

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Objective: To determine how short-latency stretch reflex amplitude in the soleus muscle is modulated by cold stimulation in able-bodied individuals and individuals with complete spinal cord injury. Methods: An initial 100-s baseline period was followed by 50-s cold stimulation periods. Stretch reflex of the right soleus muscle was elicited for 10-s intervals, while cold stimulation was applied to the left thigh. Results: Peak-to-peak amplitude of the stretch reflex increased significantly during cold stimulation up to 127 ± 21% of the baseline in the able-bodied group (n= 9, P< 0.01). Similarly, stretch reflex increased up to 125 ± 11% in a group with injury level at or below thoracic 10 (n= 4), although this increase was not significant. On the other hand, stretch reflex decreased significantly down to 78 ± 20% in a group with injury level at or above thoracic 6 (n= 8, P< 0.05). Conclusions: Effect of afferent inputs induced by cold stimulation on stretch reflex modulation is different depending on the extent of central nervous systems participating in the modulation. Significance: Our findings provide a better understanding of some basic changes in afferent-efferent spinal reflex pathways which are probably not monosynaptic in nature.

Original languageEnglish
Pages (from-to)163-170
Number of pages8
JournalClinical Neurophysiology
Volume122
Issue number1
DOIs
Publication statusPublished - 2011 Jan

Keywords

  • Autonomic dysreflexia
  • Cardiovascular
  • Somatic nervous system
  • Spinal cord injuries
  • Sympathetic nervous system

ASJC Scopus subject areas

  • Clinical Neurology
  • Neurology
  • Physiology (medical)
  • Sensory Systems

Cite this

Effect of spinal cord injury and its lesion level on stretch reflex modulation by cold stimulation in humans. / Ogata, H.; Sayenko, D. G.; Yamamoto, E.; Kitamura, T.; Yamamoto, Shinichirou; Miyoshi, T.; Kamibayashi, K.; Nakazawa, K.

In: Clinical Neurophysiology, Vol. 122, No. 1, 01.2011, p. 163-170.

Research output: Contribution to journalArticle

Ogata, H, Sayenko, DG, Yamamoto, E, Kitamura, T, Yamamoto, S, Miyoshi, T, Kamibayashi, K & Nakazawa, K 2011, 'Effect of spinal cord injury and its lesion level on stretch reflex modulation by cold stimulation in humans', Clinical Neurophysiology, vol. 122, no. 1, pp. 163-170. https://doi.org/10.1016/j.clinph.2010.05.028
Ogata, H. ; Sayenko, D. G. ; Yamamoto, E. ; Kitamura, T. ; Yamamoto, Shinichirou ; Miyoshi, T. ; Kamibayashi, K. ; Nakazawa, K. / Effect of spinal cord injury and its lesion level on stretch reflex modulation by cold stimulation in humans. In: Clinical Neurophysiology. 2011 ; Vol. 122, No. 1. pp. 163-170.
@article{f111d01b516741d896c06ba331c1380a,
title = "Effect of spinal cord injury and its lesion level on stretch reflex modulation by cold stimulation in humans",
abstract = "Objective: To determine how short-latency stretch reflex amplitude in the soleus muscle is modulated by cold stimulation in able-bodied individuals and individuals with complete spinal cord injury. Methods: An initial 100-s baseline period was followed by 50-s cold stimulation periods. Stretch reflex of the right soleus muscle was elicited for 10-s intervals, while cold stimulation was applied to the left thigh. Results: Peak-to-peak amplitude of the stretch reflex increased significantly during cold stimulation up to 127 ± 21{\%} of the baseline in the able-bodied group (n= 9, P< 0.01). Similarly, stretch reflex increased up to 125 ± 11{\%} in a group with injury level at or below thoracic 10 (n= 4), although this increase was not significant. On the other hand, stretch reflex decreased significantly down to 78 ± 20{\%} in a group with injury level at or above thoracic 6 (n= 8, P< 0.05). Conclusions: Effect of afferent inputs induced by cold stimulation on stretch reflex modulation is different depending on the extent of central nervous systems participating in the modulation. Significance: Our findings provide a better understanding of some basic changes in afferent-efferent spinal reflex pathways which are probably not monosynaptic in nature.",
keywords = "Autonomic dysreflexia, Cardiovascular, Somatic nervous system, Spinal cord injuries, Sympathetic nervous system",
author = "H. Ogata and Sayenko, {D. G.} and E. Yamamoto and T. Kitamura and Shinichirou Yamamoto and T. Miyoshi and K. Kamibayashi and K. Nakazawa",
year = "2011",
month = "1",
doi = "10.1016/j.clinph.2010.05.028",
language = "English",
volume = "122",
pages = "163--170",
journal = "Clinical Neurophysiology",
issn = "1388-2457",
publisher = "Elsevier Ireland Ltd",
number = "1",

}

TY - JOUR

T1 - Effect of spinal cord injury and its lesion level on stretch reflex modulation by cold stimulation in humans

AU - Ogata, H.

AU - Sayenko, D. G.

AU - Yamamoto, E.

AU - Kitamura, T.

AU - Yamamoto, Shinichirou

AU - Miyoshi, T.

AU - Kamibayashi, K.

AU - Nakazawa, K.

PY - 2011/1

Y1 - 2011/1

N2 - Objective: To determine how short-latency stretch reflex amplitude in the soleus muscle is modulated by cold stimulation in able-bodied individuals and individuals with complete spinal cord injury. Methods: An initial 100-s baseline period was followed by 50-s cold stimulation periods. Stretch reflex of the right soleus muscle was elicited for 10-s intervals, while cold stimulation was applied to the left thigh. Results: Peak-to-peak amplitude of the stretch reflex increased significantly during cold stimulation up to 127 ± 21% of the baseline in the able-bodied group (n= 9, P< 0.01). Similarly, stretch reflex increased up to 125 ± 11% in a group with injury level at or below thoracic 10 (n= 4), although this increase was not significant. On the other hand, stretch reflex decreased significantly down to 78 ± 20% in a group with injury level at or above thoracic 6 (n= 8, P< 0.05). Conclusions: Effect of afferent inputs induced by cold stimulation on stretch reflex modulation is different depending on the extent of central nervous systems participating in the modulation. Significance: Our findings provide a better understanding of some basic changes in afferent-efferent spinal reflex pathways which are probably not monosynaptic in nature.

AB - Objective: To determine how short-latency stretch reflex amplitude in the soleus muscle is modulated by cold stimulation in able-bodied individuals and individuals with complete spinal cord injury. Methods: An initial 100-s baseline period was followed by 50-s cold stimulation periods. Stretch reflex of the right soleus muscle was elicited for 10-s intervals, while cold stimulation was applied to the left thigh. Results: Peak-to-peak amplitude of the stretch reflex increased significantly during cold stimulation up to 127 ± 21% of the baseline in the able-bodied group (n= 9, P< 0.01). Similarly, stretch reflex increased up to 125 ± 11% in a group with injury level at or below thoracic 10 (n= 4), although this increase was not significant. On the other hand, stretch reflex decreased significantly down to 78 ± 20% in a group with injury level at or above thoracic 6 (n= 8, P< 0.05). Conclusions: Effect of afferent inputs induced by cold stimulation on stretch reflex modulation is different depending on the extent of central nervous systems participating in the modulation. Significance: Our findings provide a better understanding of some basic changes in afferent-efferent spinal reflex pathways which are probably not monosynaptic in nature.

KW - Autonomic dysreflexia

KW - Cardiovascular

KW - Somatic nervous system

KW - Spinal cord injuries

KW - Sympathetic nervous system

UR - http://www.scopus.com/inward/record.url?scp=78650175146&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=78650175146&partnerID=8YFLogxK

U2 - 10.1016/j.clinph.2010.05.028

DO - 10.1016/j.clinph.2010.05.028

M3 - Article

C2 - 20580311

AN - SCOPUS:78650175146

VL - 122

SP - 163

EP - 170

JO - Clinical Neurophysiology

JF - Clinical Neurophysiology

SN - 1388-2457

IS - 1

ER -