The effect of vibration on skin microcirculation was studied to investigate the possibility of clinical use of vibration to prevent and treat pressure ulcers. Vibrations at a vibrational intensity of 600, 800, or 1,000 mVpp with a fixed frequency of 47Hz were applied horizontally to the ear of male hairless mice (n = 6 for each group) under inhalation anesthesia. The control group (n = 6) received no vibrations. Venular blood flow was measured by an intravital videomicroscope at the baseline and at 0, 5, and 15min after the application of vibrations. A significant increase was observed in the 600 mVpp group 5 and 15min after vibration in comparison to the control group (P = 0.002 and P = 0.046, respectively). We also detected increased blood flow in the 800 mVpp group (P = 0.028) and the 1,000 mVpp group (P = 0.012) 5min after vibration; however, these increases attenuated after 15min. These results indicate that direct skin vibration at a frequency of 47Hz improves skin blood flow. The present study gives further support to the role of vibration on a short-term increase in skin blood flow.
|Number of pages||6|
|Publication status||Published - 2007 Dec 1|
- Chronic wound
- Intravital videomicroscope
ASJC Scopus subject areas
- Health(social science)
- Biochemistry, Genetics and Molecular Biology(all)