Abstract
Various 2-oxazolidinones were galvanostatically electrooxidized in the presence of various fluoride salts. It was found that a fluorine atom was introduced to the α-position of the nitrogen atom of N-acyl- and N-alkoxycarbonyl-2-oxazolidinones to provide the corresponding α-fluorinated products in moderate to good yields. In the case of N-phenoxycarbonyl derivative, fluorination took place on the phenyl group selectively.
Original language | English |
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Pages (from-to) | 6854-6859 |
Number of pages | 6 |
Journal | Tetrahedron |
Volume | 61 |
Issue number | 28 |
DOIs | |
Publication status | Published - 2005 Jul 11 |
Externally published | Yes |
Keywords
- 2-Oxazolidinone
- Electrochemical fluorination
- Fluorinated 2-oxazolidinone
- Partial fluorination
ASJC Scopus subject areas
- Biochemistry
- Drug Discovery
- Organic Chemistry