Electrolytic partial fluorination of organic compounds. Part 78: Regioselective anodic fluorination of 2-oxazolidinones

Yi Cao; Katsutoshi Suzuki; Toshiki Tajima; Toshio Fuchigami

doi:10.1016/j.tet.2005.04.057

Electrolytic partial fluorination of organic compounds. Part 78: Regioselective anodic fluorination of 2-oxazolidinones

Yi Cao, Katsutoshi Suzuki, Toshiki Tajima, Toshio Fuchigami

Research output: Contribution to journal › Article

10 Citations (Scopus)

Abstract

Various 2-oxazolidinones were galvanostatically electrooxidized in the presence of various fluoride salts. It was found that a fluorine atom was introduced to the α-position of the nitrogen atom of N-acyl- and N-alkoxycarbonyl-2-oxazolidinones to provide the corresponding α-fluorinated products in moderate to good yields. In the case of N-phenoxycarbonyl derivative, fluorination took place on the phenyl group selectively.

Original language	English
Pages (from-to)	6854-6859
Number of pages	6
Journal	Tetrahedron
Volume	61
Issue number	28
DOIs	https://doi.org/10.1016/j.tet.2005.04.057
Publication status	Published - 2005 Jul 11

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Keywords

2-Oxazolidinone
Electrochemical fluorination
Fluorinated 2-oxazolidinone
Partial fluorination

ASJC Scopus subject areas

Biochemistry
Drug Discovery
Organic Chemistry

Cite this

Cao, Y., Suzuki, K., Tajima, T., & Fuchigami, T. (2005). Electrolytic partial fluorination of organic compounds. Part 78: Regioselective anodic fluorination of 2-oxazolidinones. Tetrahedron, 61(28), 6854-6859. https://doi.org/10.1016/j.tet.2005.04.057

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Access to Document

10.1016/j.tet.2005.04.057