Electrolytic partial fluorination of organic compounds. Part 78: Regioselective anodic fluorination of 2-oxazolidinones

Yi Cao, Katsutoshi Suzuki, Toshiki Tajima, Toshio Fuchigami

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10 Citations (Scopus)


Various 2-oxazolidinones were galvanostatically electrooxidized in the presence of various fluoride salts. It was found that a fluorine atom was introduced to the α-position of the nitrogen atom of N-acyl- and N-alkoxycarbonyl-2-oxazolidinones to provide the corresponding α-fluorinated products in moderate to good yields. In the case of N-phenoxycarbonyl derivative, fluorination took place on the phenyl group selectively.

Original languageEnglish
Pages (from-to)6854-6859
Number of pages6
Issue number28
Publication statusPublished - 2005 Jul 11



  • 2-Oxazolidinone
  • Electrochemical fluorination
  • Fluorinated 2-oxazolidinone
  • Partial fluorination

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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