Abstract
The iodocarbocyclization of4-pentenylmalonate derivatives1 proceeded with moderate to high enantiomeric excesses (up to 85 %ee) by treating1 with I2 and CuO in the presence of the chiral titanium alkoxide2. The present reaction should serve as a new method for enantioselective construction of functionalized cyclopentane derivatives.
Original language | English |
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Pages (from-to) | 1479-1482 |
Number of pages | 4 |
Journal | Tetrahedron Letters |
Volume | 36 |
Issue number | 9 |
DOIs | |
Publication status | Published - 1995 Feb 27 |
Externally published | Yes |
ASJC Scopus subject areas
- Biochemistry
- Drug Discovery
- Organic Chemistry