Abstract
The iodocarbocyclization of4-pentenylmalonate derivatives1 proceeded with moderate to high enantiomeric excesses (up to 85 %ee) by treating1 with I2 and CuO in the presence of the chiral titanium alkoxide2. The present reaction should serve as a new method for enantioselective construction of functionalized cyclopentane derivatives.
| Original language | English |
|---|---|
| Pages (from-to) | 1479-1482 |
| Number of pages | 4 |
| Journal | Tetrahedron Letters |
| Volume | 36 |
| Issue number | 9 |
| DOIs | |
| Publication status | Published - 1995 Feb 27 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Biochemistry
- Organic Chemistry
- Drug Discovery
Cite this
Enantioselective iodocarbocyclization of 4-alkenylmalonate derivatives using a chiral titanium complex. / Inoue, Tadashi; Kitagawa, Osamu; Kurumizawa, Shigeyuki; Ochiai, Orie; Taguchi, Takeo.
In: Tetrahedron Letters, Vol. 36, No. 9, 27.02.1995, p. 1479-1482.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Enantioselective iodocarbocyclization of 4-alkenylmalonate derivatives using a chiral titanium complex
AU - Inoue, Tadashi
AU - Kitagawa, Osamu
AU - Kurumizawa, Shigeyuki
AU - Ochiai, Orie
AU - Taguchi, Takeo
PY - 1995/2/27
Y1 - 1995/2/27
N2 - The iodocarbocyclization of4-pentenylmalonate derivatives1 proceeded with moderate to high enantiomeric excesses (up to 85 %ee) by treating1 with I2 and CuO in the presence of the chiral titanium alkoxide2. The present reaction should serve as a new method for enantioselective construction of functionalized cyclopentane derivatives.
AB - The iodocarbocyclization of4-pentenylmalonate derivatives1 proceeded with moderate to high enantiomeric excesses (up to 85 %ee) by treating1 with I2 and CuO in the presence of the chiral titanium alkoxide2. The present reaction should serve as a new method for enantioselective construction of functionalized cyclopentane derivatives.
UR - http://www.scopus.com/inward/record.url?scp=0028911544&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0028911544&partnerID=8YFLogxK
U2 - 10.1016/0040-4039(95)00064-J
DO - 10.1016/0040-4039(95)00064-J
M3 - Article
AN - SCOPUS:0028911544
VL - 36
SP - 1479
EP - 1482
JO - Tetrahedron Letters
JF - Tetrahedron Letters
SN - 0040-4039
IS - 9
ER -