Enhancement of surface plasmon resonance sensing for DNA hybridization using colloidal Au attached probe DNA

Akira Yamaguchi, Saulius Juodkazis, Shigeki Matsuo, Hiroaki Misawa

Research output: Contribution to journalArticlepeer-review

24 Citations (Scopus)

Abstract

In this study, we demonstrate that the Au particle modified probe DNA monolayer can enhance the surface plasmon resonance (SPR) signal for measuring hybridization of unlabeled DNA molecules. The Au particles adsorbed on single stranded (ss)- and double stranded (ds)-DNA monolayers have different optical interaction with surface of Au thin film, and this difference induces the enhancement of the SPR signal.

Original languageEnglish
Pages (from-to)190-191
Number of pages2
JournalChemistry Letters
Issue number2
DOIs
Publication statusPublished - 2002 Feb 5
Externally publishedYes

ASJC Scopus subject areas

  • Chemistry(all)

Fingerprint

Dive into the research topics of 'Enhancement of surface plasmon resonance sensing for DNA hybridization using colloidal Au attached probe DNA'. Together they form a unique fingerprint.

Cite this