Estimation of nonlinear elasticity parameter of tissues by ultrasound

Naotaka Nitta, Tsuyoshi Shiina

Research output: Contribution to journalArticlepeer-review

23 Citations (Scopus)

Abstract

In this paper, a new parameter that quantifies the intensity of tissue nonlinear elasticity is introduced as the nonlinear elasticity parameter. This parameter is defined based on the empirical information that the nonlinear elastic behavior of soft tissues exhibits an exponential character. To visualize the quantitative nonlinear elasticity parameter, an ultrasonic imaging procedure involving the three-dimensional finite element method (3-D FEM) is presented. Experimental investigations that visualize the nonlinear elasticity parameter distribution of a chicken gizzard and a pig kidney embedded in a gelatin-based phantom were performed. The values extracted by ultrasound and 3-D FEM were compared with those measured by the direct mechanical compression test. Experimental results revealed that the nonlinear elasticity parameter values extracted by ultrasound and 3-D FEM exhibited good agreement with those measured by the mechanical compression test, and that the intensity of tissue nonlinear elasticity could be visualized quantitatively by the defined nonlinear elasticity parameter.

Original languageEnglish
Pages (from-to)3572-3578
Number of pages7
JournalJapanese Journal of Applied Physics, Part 1: Regular Papers and Short Notes and Review Papers
Volume41
Issue number5 B
DOIs
Publication statusPublished - 2002 May
Externally publishedYes

Keywords

  • Exponential function
  • Nonlinear elasticity parameter
  • Phantom experiment
  • Quantitative measurement
  • Three-dimensional finite element method

ASJC Scopus subject areas

  • Engineering(all)
  • Physics and Astronomy(all)

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