Experimental investigation of 2D myocardial strain imaging

Kengo Kondo, Makoto Yamakawa, Tsuyoshi Shiina, Naotaka Nitta

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)

Abstract

Abnormal regional wall-motion often appears in the early stages of ischemic heart disease such as angina pectoris and cardiac infarction. Therefore, it is very important to accurately estimate multi-dimensional displacements in order to precisely diagnose ischemic heart disease. There are various estimation methods for measuring tissue displacement, but most of them estimate only the component of the 3-D displacement vector along the beam direction, making it difficult to correctly assess the abnormality of regional myocardial contraction using these conventional methods. We have proposed a Weighted-Phase Gradient Method (WPGM) for measuring 3-D displacement vectors regardless of the direction of movement. We obtained a strain tensor from the displacement vector and subsequently investigated 2- D and 3-D myocardial strain imaging by displaying parameters for regional myocardial contraction derived from components of the strain tensor. First, the validity of the 2-D and 3-D myocardial strain imaging was confirmed by numerical simulation using normal and ischemic myocardial models. Next, we evaluated the feasibility of 2-D myocardial strain imaging through phantom experiments. A phantom of the left ventricle was made from cylindrical konnyaku with a hollow. A balloon was inserted and controlled by a hydraulic pump in order to expand the ventricle. Echo data from the phantom corresponding to the short-axis cross section was received by a linear-array probe with a center frequency of 5MHz, using a 64-channel amplifier to control each element individually. Received echoes were processed into a 2-D displacement vector and strain or parameters for regional myocardial contraction using the proposed method. As a result, a 2-D displacement vector and strain images corresponding to the predicted deformation were obtained. These results validated the feasibility of the proposed method.

Original languageEnglish
Title of host publicationIFMBE Proceedings
EditorsSun I. Kim, Tae Suk Suh
PublisherSpringer Verlag
Pages1587-1590
Number of pages4
Edition1
ISBN (Print)9783540368397
DOIs
Publication statusPublished - 2007
Externally publishedYes
Event10th World Congress on Medical Physics and Biomedical Engineering, WC 2006 - Seoul, Korea, Republic of
Duration: 2006 Aug 272006 Sep 1

Publication series

NameIFMBE Proceedings
Number1
Volume14
ISSN (Print)1680-0737
ISSN (Electronic)1433-9277

Conference

Conference10th World Congress on Medical Physics and Biomedical Engineering, WC 2006
Country/TerritoryKorea, Republic of
CitySeoul
Period06/8/2706/9/1

Keywords

  • Myocardial asynergy
  • Strain imaging
  • Weighted-phase gradient method

ASJC Scopus subject areas

  • Bioengineering
  • Biomedical Engineering

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