Abstract
Microtubules, which are flexible biopolymers, can be used for nanotechnology applications (e.g., nano-actuator) as they have a rigidity similar to that of plexyglass and other plastic materials. The flexural rigidity, or bending stiffness, of nucrotubules was measured using a laser trapping technique and dark-field microscopy. One end of a microtubule rod was chemically bound to a glass microsphere, while the other end was bound to a silica glass substrate. Then, the microsphere was lasertrapped and manipulated to exert three different deformation modes on the microtubule. The values of flexural rigidity for these deformations were between 10-25 and 10-23 Nm2 as measured for the 5-25 μm length microtubules. The origin of the length dependence of the flexural rigidity of microtubules is discussed.
| Original language | English |
|---|---|
| Pages (from-to) | 3015-3019 |
| Number of pages | 5 |
| Journal | Japanese Journal of Applied Physics, Part 1: Regular Papers and Short Notes and Review Papers |
| Volume | 41 |
| Issue number | 5 A |
| Publication status | Published - 2002 May |
| Externally published | Yes |
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Keywords
- Flexural rigidity
- Laser manipulation
- Laser trapping
- Laser tweezers
- Microtubule-associated proteins
- Radiation force
ASJC Scopus subject areas
- Physics and Astronomy (miscellaneous)
Cite this
Flexural rigidity of a single microtubule. / Takasone, Toru; Juodkazis, Saulius; Kawagishi, Yuji; Yamaguchi, Akira; Matsuo, Shigeki; Sakakibara, Hitoshi; Nakayama, Haruto; Misawa, Hiroaki.
In: Japanese Journal of Applied Physics, Part 1: Regular Papers and Short Notes and Review Papers, Vol. 41, No. 5 A, 05.2002, p. 3015-3019.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Flexural rigidity of a single microtubule
AU - Takasone, Toru
AU - Juodkazis, Saulius
AU - Kawagishi, Yuji
AU - Yamaguchi, Akira
AU - Matsuo, Shigeki
AU - Sakakibara, Hitoshi
AU - Nakayama, Haruto
AU - Misawa, Hiroaki
PY - 2002/5
Y1 - 2002/5
N2 - Microtubules, which are flexible biopolymers, can be used for nanotechnology applications (e.g., nano-actuator) as they have a rigidity similar to that of plexyglass and other plastic materials. The flexural rigidity, or bending stiffness, of nucrotubules was measured using a laser trapping technique and dark-field microscopy. One end of a microtubule rod was chemically bound to a glass microsphere, while the other end was bound to a silica glass substrate. Then, the microsphere was lasertrapped and manipulated to exert three different deformation modes on the microtubule. The values of flexural rigidity for these deformations were between 10-25 and 10-23 Nm2 as measured for the 5-25 μm length microtubules. The origin of the length dependence of the flexural rigidity of microtubules is discussed.
AB - Microtubules, which are flexible biopolymers, can be used for nanotechnology applications (e.g., nano-actuator) as they have a rigidity similar to that of plexyglass and other plastic materials. The flexural rigidity, or bending stiffness, of nucrotubules was measured using a laser trapping technique and dark-field microscopy. One end of a microtubule rod was chemically bound to a glass microsphere, while the other end was bound to a silica glass substrate. Then, the microsphere was lasertrapped and manipulated to exert three different deformation modes on the microtubule. The values of flexural rigidity for these deformations were between 10-25 and 10-23 Nm2 as measured for the 5-25 μm length microtubules. The origin of the length dependence of the flexural rigidity of microtubules is discussed.
KW - Flexural rigidity
KW - Laser manipulation
KW - Laser trapping
KW - Laser tweezers
KW - Microtubule-associated proteins
KW - Radiation force
UR - http://www.scopus.com/inward/record.url?scp=0036578222&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0036578222&partnerID=8YFLogxK
M3 - Article
AN - SCOPUS:0036578222
VL - 41
SP - 3015
EP - 3019
JO - Japanese Journal of Applied Physics, Part 1: Regular Papers & Short Notes
JF - Japanese Journal of Applied Physics, Part 1: Regular Papers & Short Notes
SN - 0021-4922
IS - 5 A
ER -