Fluorescent cyclodextrin immobilized on a cellulose membrane as a chemosensor system for detecting molecules

T. Tanabe, K. Touma, K. Hamasaki, A. Ueno

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Dansyl glutamate-modified cyclodextrin (DnsGlu-β-CD) was prepared as a fluorescent host, which is capable of being immobilized on a cellulose membrane (DnsGlu-β-CD-membrane). The fluorescence intensity of DnsGlu-β-CD decreased with increasing concentration of guest molecules, indicating that the host changes the location of the dansyl group from inside to outside the cyclodextrin cavity upon guest accommodation. Similar guest-induced decrease in the fluorescence intensity was observed for DnsGlu-β-CD immobilized to a cellulose membrane. This result demonstrates that the cellulose membrane may be used as a practical supporting material of various chromophore-modified cyclodextrins and that DnsGlu-β-CD-membrane is useful as a novel disposable chemosensor for molecules.

Original languageEnglish
Pages (from-to)1877-1880
Number of pages4
JournalAnalytical Chemistry
Issue number8
Publication statusPublished - 2001 Apr 15


ASJC Scopus subject areas

  • Analytical Chemistry

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