@inproceedings{4b07fd4f3d6f419ea6fc5fa8e46e4f04,
title = "Fluorometric bio-sniffer (gas phase biosensor) for breath acetone as a volatile product of lipid metabolism",
abstract = "A highly sensitive acetone bio-sniffer (biochemical gas sensor) for assessment of lipid metabolism utilizing reverse reaction of secondary alcohol dehydrogenase was fabricated and demonstrated. This bio-sniffer consisted of a NADH fluorescence detection system, a flow-cell section, and an enzyme-immobilized membrane. This bio-sniffer presented rapid response, highly sensitivity and selectivity. The analyses of breath acetone concentrations during fasting and aerobic exercise were also demonstrated. The results showed that the breath acetone concentration would increase during long-time fasting and aerobic exercise. This acetone bio-sniffer provides a new kind of analytical tool for non-invasive evaluation of human lipid metabolism and it is also expected to use for the clinical applications such as monitoring the progression of diabetes.",
author = "Chien, {Po Jen} and Ming Ye and Takuma Suzuki and Koji Toma and Takahiro Arakawa and Kohji Mitsubayashi",
note = "Publisher Copyright: {\textcopyright} The Electrochemical Society.; Symposium on Chemical Sensors 12: Chemical and Biological Sensors and Analytical Systems - PRiME 2016/230th ECS Meeting ; Conference date: 02-10-2016 Through 07-10-2016",
year = "2016",
doi = "10.1149/07516.0047ecst",
language = "English",
series = "ECS Transactions",
publisher = "Electrochemical Society Inc.",
number = "16",
pages = "47--51",
editor = "M. Carter and Y. Shimizu and Lee, {W. Y.} and T. Yasukawa and R. Mukundan and Simonian, {A. L.} and Nagahara, {L. A.} and O. Niwa and Chin, {B. A.}",
booktitle = "Chemical Sensors 12",
edition = "16",
}