Functional optical coherence tomography reveals localized layer-specific activations in cat primary visual cortex in vivo

Uma Maheswari Rajagopalan, Manabu Tanifuji

Research output: Contribution to journalArticlepeer-review

23 Citations (Scopus)

Abstract

Surface neural activity has been widely visualized using optical intrinsic signal imaging (OISI) from various cortical sensory areas. OISI of the cortical surface with a CCD camera gives integrated information across a depth of a few hundred micrometers. We visualize depth-resolved activation patterns of cat primary visual cortex by functional optical coherence tomography (fOCT). A comparison of the depth-integrated results of fOCT maps with the optical intrinsic signal profiles shows fairly good agreement. Our results reveal layerspecific activation patterns and indicate that the activation was not homogeneous.

Original languageEnglish
Pages (from-to)2614-2616
Number of pages3
JournalOptics Letters
Volume32
Issue number17
DOIs
Publication statusPublished - 2007 Sep 1

ASJC Scopus subject areas

  • Atomic and Molecular Physics, and Optics

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