Functional optical coherence tomography to reveal functional architecture of cat visual cortex in vivo

Uma Maheswari Rajagopalan, Ryota Homma, Hirofumi Kadono, Manabu Tanifuji

Research output: Contribution to journalConference article

1 Citation (Scopus)


Optical intrinsic signal imaging (OISI) provides the surface activation map of brain and has provided many insights. In this study, we show that the optical coherence tomography (OCT) can provide depth resolved functional map of cat visual cortex. Activation profile obtained by integrating OCT signal across depth correlates well with that determined by the OISI. Functional OCT (fOCT) promises to be a valid technique for revealing unexplored organization inside the brain at a micro system level.

Original languageEnglish
Pages (from-to)77-83
Number of pages7
JournalProceedings of SPIE - The International Society for Optical Engineering
Publication statusPublished - 2003 Dec 1
EventOptical Coherence Tomography and Coherence Techniques - Munich, Germany
Duration: 2003 Jun 222003 Jun 24



  • Depth resolved functional profile
  • Functional optical coherence tomography
  • Neural activity
  • Optical coherence tomography
  • Optical intrinsic signal imaging
  • Primary visual cortex
  • Scattering change
  • Volumetric functional imaging

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Computer Science Applications
  • Applied Mathematics
  • Electrical and Electronic Engineering

Cite this