Fundamental study for identification and elimination of reflection artifacts with photoacoustic spectrum

Y. Nakao, T. Namita, K. Kengo, M. Yamakawa, T. Shiina

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Photoacoustic imaging can show the distribution of vessels and the degree of oxygen saturation, reliably supporting diagnoses of complaints such as cancer and articular rheumatism. Our handheld imaging system for percutaneous photoacoustic imaging and ultrasound imaging can take measurements easily. However, an important difficulty remains: reflection artifacts degrade the image quality. Reflection artifacts arise when photoacoustic waves from signal source reflect at the tissue boundary and are detected using a handheld probe. To address this difficulty, methods for identifying and eliminating reflection artifacts using single wavelength light have been developed.however, the detection accuracy of these methods is insufficient. On the other hand, tissue specificity of optical properties can achieve higher image quality when taking multi-wavelength measurements. We propose a method for identifying and eliminating reflection artifacts using the photoacoustic spectrum in multi-wavelength measurements. The photoacoustic signal intensity is wavelength-dependent and fluence-dependent. Reflection artifacts’ spectra are similar to that of the upper signal source. The spectrum of the signal source at the same depth as reflection artifact differs from the upper signal source. We took multi-wavelength measurements of a phantom mimicking vessels using piano wire in deaerated water including black ink or Intralipid of various consistencies. We then compared the photoacoustic spectra of piano wire and reflection artifacts by calculating root mean square (RMS). Results show that the reflection artifact spectrum and the upper signal source spectrum are more similar than the lower photoacoustic signal source spectrum. These analyses underscore the potential of this method for identifying and eliminating reflection artifacts.

Original languageEnglish
Title of host publicationEuropean Conference on Biomedical Optics, ECBO_2019
PublisherOSA - The Optical Society
ISBN (Electronic)9781557528209
DOIs
Publication statusPublished - 2019
Externally publishedYes
EventEuropean Conference on Biomedical Optics, ECBO_2019 - Munich, Netherlands
Duration: 2019 Jun 232019 Jun 25

Publication series

NameOptics InfoBase Conference Papers
VolumePart F142-ECBO 2019

Conference

ConferenceEuropean Conference on Biomedical Optics, ECBO_2019
Country/TerritoryNetherlands
CityMunich
Period19/6/2319/6/25

Keywords

  • Bioimaging
  • Clutter noise
  • Handheld
  • Multi-wavelength
  • Optoacoustic

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Mechanics of Materials

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