High-intensity static magnetic fields modulate skin microcirculation and temperature in vivo

Shigeru Ichioka, Masayuki Minegishi, Masakazu Iwasaka, Masahiro Shibata, Takashi Nakatsuka, Kiyonori Harii, Akira Kamiya, Shoogo Ueno

Research output: Contribution to journalArticle

54 Citations (Scopus)

Abstract

We investigated the acute effect of static magnetic fields of up to 8 T on skin blood flow and body temperature in anesthetized rats. These variables were measured prior to, during, and following exposure to a magnetic field in a superconducting magnet with a horizontal bore. The dorsal skin was transversely incised for 1 cm to make a subcutaneous pocket. Probes of a laser Doppler flowmeter and a thermistor were inserted into the pocket and positioned at mid-dorsum to measure skin blood flow and temperature. Another thermistor probe was put into the rectum to monitor rectal temperature. After baseline measurement outside the magnet, the rat was inserted into the bore for 20 min so that mid-dorsum was exactly positioned at the center, where the magnetic field was nearly homogeneous. Post-exposure changes were then recorded for 20 min outside the bore. Sham-exposed animals were submitted to exactly the same conditions, except that the superconducting magnet was not energized. Skin blood flow and temperature decreased significantly during magnetic field exposure and recovered after removal of the animal from the magnet. The rectal temperature showed a tendency to decrease while the animal was in the magnet. The microcirculatory and thermal reactions in the present study were consistent and agreed with some of the predictions based on mathematical simulations and model experiments. Bioelectromagnetics 21:183-188, 2000.

Original languageEnglish
Pages (from-to)183-188
Number of pages6
JournalBioelectromagnetics
Volume21
Issue number3
Publication statusPublished - 2000 Apr
Externally publishedYes

Fingerprint

magnetic fields
skin (animal)
blood flow
temperature
probes (equipment)
flowmeters
animals
rats
acute effects
rectum
body temperature
lasers
magnetic materials
heat
prediction
monitoring

Keywords

  • Blood flow
  • Laser Doppler flowmetry
  • Magnetic field exposure
  • Microcirculation
  • Superconducting magnet

ASJC Scopus subject areas

  • Agricultural and Biological Sciences (miscellaneous)
  • Biophysics

Cite this

Ichioka, S., Minegishi, M., Iwasaka, M., Shibata, M., Nakatsuka, T., Harii, K., ... Ueno, S. (2000). High-intensity static magnetic fields modulate skin microcirculation and temperature in vivo. Bioelectromagnetics, 21(3), 183-188.

High-intensity static magnetic fields modulate skin microcirculation and temperature in vivo. / Ichioka, Shigeru; Minegishi, Masayuki; Iwasaka, Masakazu; Shibata, Masahiro; Nakatsuka, Takashi; Harii, Kiyonori; Kamiya, Akira; Ueno, Shoogo.

In: Bioelectromagnetics, Vol. 21, No. 3, 04.2000, p. 183-188.

Research output: Contribution to journalArticle

Ichioka, S, Minegishi, M, Iwasaka, M, Shibata, M, Nakatsuka, T, Harii, K, Kamiya, A & Ueno, S 2000, 'High-intensity static magnetic fields modulate skin microcirculation and temperature in vivo', Bioelectromagnetics, vol. 21, no. 3, pp. 183-188.
Ichioka S, Minegishi M, Iwasaka M, Shibata M, Nakatsuka T, Harii K et al. High-intensity static magnetic fields modulate skin microcirculation and temperature in vivo. Bioelectromagnetics. 2000 Apr;21(3):183-188.
Ichioka, Shigeru ; Minegishi, Masayuki ; Iwasaka, Masakazu ; Shibata, Masahiro ; Nakatsuka, Takashi ; Harii, Kiyonori ; Kamiya, Akira ; Ueno, Shoogo. / High-intensity static magnetic fields modulate skin microcirculation and temperature in vivo. In: Bioelectromagnetics. 2000 ; Vol. 21, No. 3. pp. 183-188.
@article{c04b079e094541d6874d2472238481fb,
title = "High-intensity static magnetic fields modulate skin microcirculation and temperature in vivo",
abstract = "We investigated the acute effect of static magnetic fields of up to 8 T on skin blood flow and body temperature in anesthetized rats. These variables were measured prior to, during, and following exposure to a magnetic field in a superconducting magnet with a horizontal bore. The dorsal skin was transversely incised for 1 cm to make a subcutaneous pocket. Probes of a laser Doppler flowmeter and a thermistor were inserted into the pocket and positioned at mid-dorsum to measure skin blood flow and temperature. Another thermistor probe was put into the rectum to monitor rectal temperature. After baseline measurement outside the magnet, the rat was inserted into the bore for 20 min so that mid-dorsum was exactly positioned at the center, where the magnetic field was nearly homogeneous. Post-exposure changes were then recorded for 20 min outside the bore. Sham-exposed animals were submitted to exactly the same conditions, except that the superconducting magnet was not energized. Skin blood flow and temperature decreased significantly during magnetic field exposure and recovered after removal of the animal from the magnet. The rectal temperature showed a tendency to decrease while the animal was in the magnet. The microcirculatory and thermal reactions in the present study were consistent and agreed with some of the predictions based on mathematical simulations and model experiments. Bioelectromagnetics 21:183-188, 2000.",
keywords = "Blood flow, Laser Doppler flowmetry, Magnetic field exposure, Microcirculation, Superconducting magnet",
author = "Shigeru Ichioka and Masayuki Minegishi and Masakazu Iwasaka and Masahiro Shibata and Takashi Nakatsuka and Kiyonori Harii and Akira Kamiya and Shoogo Ueno",
year = "2000",
month = "4",
language = "English",
volume = "21",
pages = "183--188",
journal = "Bioelectromagnetics",
issn = "0197-8462",
publisher = "Wiley-Liss Inc.",
number = "3",

}

TY - JOUR

T1 - High-intensity static magnetic fields modulate skin microcirculation and temperature in vivo

AU - Ichioka, Shigeru

AU - Minegishi, Masayuki

AU - Iwasaka, Masakazu

AU - Shibata, Masahiro

AU - Nakatsuka, Takashi

AU - Harii, Kiyonori

AU - Kamiya, Akira

AU - Ueno, Shoogo

PY - 2000/4

Y1 - 2000/4

N2 - We investigated the acute effect of static magnetic fields of up to 8 T on skin blood flow and body temperature in anesthetized rats. These variables were measured prior to, during, and following exposure to a magnetic field in a superconducting magnet with a horizontal bore. The dorsal skin was transversely incised for 1 cm to make a subcutaneous pocket. Probes of a laser Doppler flowmeter and a thermistor were inserted into the pocket and positioned at mid-dorsum to measure skin blood flow and temperature. Another thermistor probe was put into the rectum to monitor rectal temperature. After baseline measurement outside the magnet, the rat was inserted into the bore for 20 min so that mid-dorsum was exactly positioned at the center, where the magnetic field was nearly homogeneous. Post-exposure changes were then recorded for 20 min outside the bore. Sham-exposed animals were submitted to exactly the same conditions, except that the superconducting magnet was not energized. Skin blood flow and temperature decreased significantly during magnetic field exposure and recovered after removal of the animal from the magnet. The rectal temperature showed a tendency to decrease while the animal was in the magnet. The microcirculatory and thermal reactions in the present study were consistent and agreed with some of the predictions based on mathematical simulations and model experiments. Bioelectromagnetics 21:183-188, 2000.

AB - We investigated the acute effect of static magnetic fields of up to 8 T on skin blood flow and body temperature in anesthetized rats. These variables were measured prior to, during, and following exposure to a magnetic field in a superconducting magnet with a horizontal bore. The dorsal skin was transversely incised for 1 cm to make a subcutaneous pocket. Probes of a laser Doppler flowmeter and a thermistor were inserted into the pocket and positioned at mid-dorsum to measure skin blood flow and temperature. Another thermistor probe was put into the rectum to monitor rectal temperature. After baseline measurement outside the magnet, the rat was inserted into the bore for 20 min so that mid-dorsum was exactly positioned at the center, where the magnetic field was nearly homogeneous. Post-exposure changes were then recorded for 20 min outside the bore. Sham-exposed animals were submitted to exactly the same conditions, except that the superconducting magnet was not energized. Skin blood flow and temperature decreased significantly during magnetic field exposure and recovered after removal of the animal from the magnet. The rectal temperature showed a tendency to decrease while the animal was in the magnet. The microcirculatory and thermal reactions in the present study were consistent and agreed with some of the predictions based on mathematical simulations and model experiments. Bioelectromagnetics 21:183-188, 2000.

KW - Blood flow

KW - Laser Doppler flowmetry

KW - Magnetic field exposure

KW - Microcirculation

KW - Superconducting magnet

UR - http://www.scopus.com/inward/record.url?scp=0034164551&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0034164551&partnerID=8YFLogxK

M3 - Article

C2 - 10723018

AN - SCOPUS:0034164551

VL - 21

SP - 183

EP - 188

JO - Bioelectromagnetics

JF - Bioelectromagnetics

SN - 0197-8462

IS - 3

ER -