High-speed freehand tissue elasticity imaging for breast diagnosis

Makoto Yamakawa, Naotaka Nitta, Tsuyoshi Shiina, Takeshi Matsumura, Satoshi Tamano, Tsuyoshi Mitake, Ei Ueno

Research output: Contribution to journalArticlepeer-review

52 Citations (Scopus)


Tissue elasticity imaging technology is expected to be a new technique for breast disease diagnosis. In clinical measurement, high-speed and freehand manipulation of the probe is required for a practical system. Thus, we developed a tissue elasticity imaging system which performs a stable strain measurement with freehand tissue compression based on the extended combined autocorrelation method. The method enables us to obtain tissue strain distribution at high-speed and suppressing errors due to lateral slip of the probe caused by freehand compression. The developed method can estimate the strain images at about 5 frames/s and was applied to breast disease measurement in vivo. Consequently, it is shown that the system is effective not only for the diagnosis of tissue hardness but also to determine the disease expansion area. It is also confirmed that the method can stably estimate the strain during the breast measurement in vivo.

Original languageEnglish
Pages (from-to)3265-3270
Number of pages6
JournalJapanese Journal of Applied Physics, Part 1: Regular Papers and Short Notes and Review Papers
Issue number5 B
Publication statusPublished - 2003 May
Externally publishedYes


  • Breast diagnosis
  • Freehand
  • High-speed
  • Strain
  • The extend combined autocorrelation method
  • Tissue elasticity

ASJC Scopus subject areas

  • Engineering(all)
  • Physics and Astronomy(all)


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