Implementation of optical coherence tomography (OCT) in visualization of functional structures of cat visual cortex

Rajagopalan Umamaheswari, H. Takaoka, R. Homma, H. Kadono, M. Tanifuji

Research output: Contribution to journalArticle

60 Citations (Scopus)

Abstract

We report the application of optical coherence tomography (OCT) for visualizing a 1D depth resolved functional structure of cat brain in vivo. The OCT system is based on the known fact that neural activation induces structural changes such as capillary dilation and cellular swelling. Detecting these changes as an amplitude change of the scattered light, an OCT signal reflecting neural activity, i.e., functional OCT (fOCT) could be obtained. Experiments have been done to obtain a depth resolved stimulus-specific profile of activation in cat visual cortex.

Original languageEnglish
Pages (from-to)47-54
Number of pages8
JournalOptics Communications
Volume202
Issue number1-3
DOIs
Publication statusPublished - 2002 Feb 1
Externally publishedYes

Fingerprint

cortexes
cats
Optical tomography
Visualization
tomography
Chemical activation
activation
swelling
stimuli
brain
Swelling
Brain
profiles
Experiments

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Atomic and Molecular Physics, and Optics
  • Physical and Theoretical Chemistry
  • Electrical and Electronic Engineering

Cite this

Implementation of optical coherence tomography (OCT) in visualization of functional structures of cat visual cortex. / Umamaheswari, Rajagopalan; Takaoka, H.; Homma, R.; Kadono, H.; Tanifuji, M.

In: Optics Communications, Vol. 202, No. 1-3, 01.02.2002, p. 47-54.

Research output: Contribution to journalArticle

@article{6d69180e3e3a46d18a840bf854fffbbc,
title = "Implementation of optical coherence tomography (OCT) in visualization of functional structures of cat visual cortex",
abstract = "We report the application of optical coherence tomography (OCT) for visualizing a 1D depth resolved functional structure of cat brain in vivo. The OCT system is based on the known fact that neural activation induces structural changes such as capillary dilation and cellular swelling. Detecting these changes as an amplitude change of the scattered light, an OCT signal reflecting neural activity, i.e., functional OCT (fOCT) could be obtained. Experiments have been done to obtain a depth resolved stimulus-specific profile of activation in cat visual cortex.",
author = "Rajagopalan Umamaheswari and H. Takaoka and R. Homma and H. Kadono and M. Tanifuji",
year = "2002",
month = "2",
day = "1",
doi = "10.1016/S0030-4018(02)01079-9",
language = "English",
volume = "202",
pages = "47--54",
journal = "Optics Communications",
issn = "0030-4018",
publisher = "Elsevier",
number = "1-3",

}

TY - JOUR

T1 - Implementation of optical coherence tomography (OCT) in visualization of functional structures of cat visual cortex

AU - Umamaheswari, Rajagopalan

AU - Takaoka, H.

AU - Homma, R.

AU - Kadono, H.

AU - Tanifuji, M.

PY - 2002/2/1

Y1 - 2002/2/1

N2 - We report the application of optical coherence tomography (OCT) for visualizing a 1D depth resolved functional structure of cat brain in vivo. The OCT system is based on the known fact that neural activation induces structural changes such as capillary dilation and cellular swelling. Detecting these changes as an amplitude change of the scattered light, an OCT signal reflecting neural activity, i.e., functional OCT (fOCT) could be obtained. Experiments have been done to obtain a depth resolved stimulus-specific profile of activation in cat visual cortex.

AB - We report the application of optical coherence tomography (OCT) for visualizing a 1D depth resolved functional structure of cat brain in vivo. The OCT system is based on the known fact that neural activation induces structural changes such as capillary dilation and cellular swelling. Detecting these changes as an amplitude change of the scattered light, an OCT signal reflecting neural activity, i.e., functional OCT (fOCT) could be obtained. Experiments have been done to obtain a depth resolved stimulus-specific profile of activation in cat visual cortex.

UR - http://www.scopus.com/inward/record.url?scp=0036468540&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0036468540&partnerID=8YFLogxK

U2 - 10.1016/S0030-4018(02)01079-9

DO - 10.1016/S0030-4018(02)01079-9

M3 - Article

AN - SCOPUS:0036468540

VL - 202

SP - 47

EP - 54

JO - Optics Communications

JF - Optics Communications

SN - 0030-4018

IS - 1-3

ER -