In vivo bone tissue formation induced by caclium phosphate paste composite with demineralized bone matrix

H. Kim, M. Park, S. Y. Lee, K. Y. Lee, H. M. Kim, S. H. Moon

Research output: Contribution to journalArticle


Demineralized bone matrix (DBM)-calcium phosphate cement (CPC) composites were subjected to cellular test of osteogenic potentials and implantation in animal model. The expression of osteogenic marker gene from mouse preosteoblast cell line MC3T3-E1 adhered to the DBM-CPC composite was much higher than plain CPC. In addition, the DBM-CPC composite implanted nude mice revealed osteoinduction between the implanted composite and adjacent tissues, whereas the plain CPC induced osteoconduction.

Original languageEnglish
Pages (from-to)1091-1094
Number of pages4
JournalKey Engineering Materials
Volume330-332 II
Publication statusPublished - 2007 Jan 24



  • Bioactivity
  • Bone formation
  • CPC
  • DBM
  • Injection
  • Paste

ASJC Scopus subject areas

  • Materials Science(all)
  • Mechanics of Materials
  • Mechanical Engineering

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