TY - GEN
T1 - In vivo evaluation of oxygen consumption by arteriolar walls in skeletal muscle
AU - Shibata, M.
PY - 2005/1/1
Y1 - 2005/1/1
N2 - To estimate the oxygen consumption rate of arteriolar walls we measured the intra- and perivascular partial oxygen tension (PO2) of arterioles in rat cremaster muscle, both at resting and vasodilating states by phosphorescence quenching technique. Using measured intra- and perivascular PO2 values, oxygen consumption rates were determined based on Krogh-Erlang analysis. We found a significant drop in PO2 in the arterioles after branching. We found that the vascular oxygen consumption rates of functional arterioles were 100-1000 times greater than those seen in in vitro experiments. These results strongly support the hypothesis that arteriolar walls consume a significant amount of oxygen as compared with the surrounding tissue. Furthermore, the reduction of vascular tone of arteriolar walls may facilitate an efficient supply of oxygen to the surrounding tissue.
AB - To estimate the oxygen consumption rate of arteriolar walls we measured the intra- and perivascular partial oxygen tension (PO2) of arterioles in rat cremaster muscle, both at resting and vasodilating states by phosphorescence quenching technique. Using measured intra- and perivascular PO2 values, oxygen consumption rates were determined based on Krogh-Erlang analysis. We found a significant drop in PO2 in the arterioles after branching. We found that the vascular oxygen consumption rates of functional arterioles were 100-1000 times greater than those seen in in vitro experiments. These results strongly support the hypothesis that arteriolar walls consume a significant amount of oxygen as compared with the surrounding tissue. Furthermore, the reduction of vascular tone of arteriolar walls may facilitate an efficient supply of oxygen to the surrounding tissue.
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U2 - 10.1109/iembs.2005.1616926
DO - 10.1109/iembs.2005.1616926
M3 - Conference contribution
AN - SCOPUS:33846918940
SN - 0780387406
SN - 9780780387409
T3 - Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings
SP - 2306
EP - 2307
BT - Proceedings of the 2005 27th Annual International Conference of the Engineering in Medicine and Biology Society, IEEE-EMBS 2005
PB - Institute of Electrical and Electronics Engineers Inc.
T2 - 2005 27th Annual International Conference of the Engineering in Medicine and Biology Society, IEEE-EMBS 2005
Y2 - 1 September 2005 through 4 September 2005
ER -