In vivo evaluation of oxygen consumption by arteriolar walls in skeletal muscle

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)

Abstract

To estimate the oxygen consumption rate of arteriolar walls we measured the intra- and perivascular partial oxygen tension (PO2) of arterioles in rat cremaster muscle, both at resting and vasodilating states by phosphorescence quenching technique. Using measured intra- and perivascular PO2 values, oxygen consumption rates were determined based on Krogh-Erlang analysis. We found a significant drop in PO2 in the arterioles after branching. We found that the vascular oxygen consumption rates of functional arterioles were 100-1000 times greater than those seen in in vitro experiments. These results strongly support the hypothesis that arteriolar walls consume a significant amount of oxygen as compared with the surrounding tissue. Furthermore, the reduction of vascular tone of arteriolar walls may facilitate an efficient supply of oxygen to the surrounding tissue.

Original languageEnglish
Title of host publicationAnnual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings
Pages2306-2307
Number of pages2
Volume7 VOLS
Publication statusPublished - 2005
Externally publishedYes
Event2005 27th Annual International Conference of the Engineering in Medicine and Biology Society, IEEE-EMBS 2005 - Shanghai
Duration: 2005 Sep 12005 Sep 4

Other

Other2005 27th Annual International Conference of the Engineering in Medicine and Biology Society, IEEE-EMBS 2005
CityShanghai
Period05/9/105/9/4

Fingerprint

Muscle
Oxygen
Tissue
Phosphorescence
Rats
Quenching
Experiments

ASJC Scopus subject areas

  • Bioengineering

Cite this

Shibata, M. (2005). In vivo evaluation of oxygen consumption by arteriolar walls in skeletal muscle. In Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings (Vol. 7 VOLS, pp. 2306-2307). [1616926]

In vivo evaluation of oxygen consumption by arteriolar walls in skeletal muscle. / Shibata, Masahiro.

Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings. Vol. 7 VOLS 2005. p. 2306-2307 1616926.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Shibata, M 2005, In vivo evaluation of oxygen consumption by arteriolar walls in skeletal muscle. in Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings. vol. 7 VOLS, 1616926, pp. 2306-2307, 2005 27th Annual International Conference of the Engineering in Medicine and Biology Society, IEEE-EMBS 2005, Shanghai, 05/9/1.
Shibata M. In vivo evaluation of oxygen consumption by arteriolar walls in skeletal muscle. In Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings. Vol. 7 VOLS. 2005. p. 2306-2307. 1616926
Shibata, Masahiro. / In vivo evaluation of oxygen consumption by arteriolar walls in skeletal muscle. Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings. Vol. 7 VOLS 2005. pp. 2306-2307
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