Indirect anodic monofluorodesulfurization of β-phenylsulfenyl β-lactams using a triarylamine mediator

T. Fuchigami, M. Tetsu, Toshiki Tajima, H. Ishii

Research output: Contribution to journalArticle

25 Citations (Scopus)

Abstract

Indirect anodic oxidation of β-phenylsulfenyl β-lactams was carried out using a catalytic amount of triarylamine as a mediator in acetonitrile containing fluoride ions; regioselective monofluorodesulfurization took place to give the corresponding β-fluorinated β-lactams in good yields. This is the first successful example of triarylamine-mediated anodic fluorodesulfurization.

Original languageEnglish
Pages (from-to)1269-1271
Number of pages3
JournalSynlett
Issue number8
Publication statusPublished - 2001
Externally publishedYes

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Keywords

  • β-lactam
  • Electrochemical fluorination
  • Fluoride salt
  • Fluorodesulfurization
  • Mediator

ASJC Scopus subject areas

  • Organic Chemistry

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