Abstract
In the presence of TiCl4 and Et3N, intramolecular carbotitanation reaction of active methine compounds having an unactivated 4-alkynyl group proceeds in a highly cis-selective manner to give methylenecyclopentane derivatives in good yields.
| Original language | English |
|---|---|
| Pages (from-to) | 7357-7360 |
| Number of pages | 4 |
| Journal | Tetrahedron Letters |
| Volume | 39 |
| Issue number | 40 |
| Publication status | Published - 1998 Oct 1 |
| Externally published | Yes |
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Keywords
- Alkynes
- Cyclization
- Cyclopentanes
- Titanium and compounds
ASJC Scopus subject areas
- Biochemistry
- Organic Chemistry
- Drug Discovery
Cite this
Kitagawa, O., Suzuki, T., Inoue, T., & Taguchi, T. (1998). Intramolecular carbotitanation reaction of active methine compounds having an unactivated alkyne mediated by TiCl4-Et3N. Tetrahedron Letters, 39(40), 7357-7360.