Iodoaziridine derivatives as novel azahomoallyl radical precursors for [3+2] cycloaddition reactions with alkenes

Osamu Kitagawa, Y. Yamada, H. Fujiwara, T. Taguchi

Research output: Contribution to journalArticle

27 Citations (Scopus)

Abstract

Functionalized pyrrolidine derivatives are accessible in good yields by radical iodine-transfer [3+2] cycloaddition of electron-rich alkenes with azahomoallyl radicals [Eq. (1)], which were generated by treating iodoaziridine derivatives with radical initiators. Ts = tosyl; 4-methylphenyl sulfonyl.

Original languageEnglish
Pages (from-to)3865-3867
Number of pages3
JournalAngewandte Chemie - International Edition
Volume40
Issue number20
DOIs
Publication statusPublished - 2001 Oct 15
Externally publishedYes

Fingerprint

Cycloaddition
Alkenes
Olefins
Derivatives
Iodine
Electrons
pyrrolidine

Keywords

  • Cycloaddition
  • Nitrogen heterocycles
  • Radical reactions
  • Synthetic methods

ASJC Scopus subject areas

  • Chemistry(all)

Cite this

Iodoaziridine derivatives as novel azahomoallyl radical precursors for [3+2] cycloaddition reactions with alkenes. / Kitagawa, Osamu; Yamada, Y.; Fujiwara, H.; Taguchi, T.

In: Angewandte Chemie - International Edition, Vol. 40, No. 20, 15.10.2001, p. 3865-3867.

Research output: Contribution to journalArticle

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